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University of Florida clinical trial failures
Review 65 stopped clinical trials from University of Florida, including disease areas, phases, and classified stop reasons.
This page groups real ClinicalTrials.gov-derived stopped trial records. The strongest added signal is the stop-reason classification: 1 of these records are likely biological failure signals, while the rest may reflect operational, strategic, regulatory, funding, enrollment, or unclear stop reasons.
Dominant stop reasons
- OPERATIONAL
- 38
- OTHER/UNKNOWN
- 24
- REGULATORY
- 2
- EFFICACY/FUTILITY
- 1
Notable sponsors
- University of Florida
- 65
Related phases
- Phase II
- 21
- Phase I
- 19
- Phase IV
- 14
- Early Phase I
- 4
- Phase III
- 4
Crawlable stopped-trial records
Open ExploreShowing up to 65 representative records from this slice. Each link opens the trial detail page with source attribution and stop-reason context.
Phase II Pain, Postoperative trial by University of Florida. Stop reason: OPERATIONAL.
PI left institution.
Phase II Anxiety trial by University of Florida. Stop reason: OPERATIONAL.
Study terminated early secondary to limited staffing resources
Phase I Melanoma trial by University of Florida. Stop reason: OTHER/UNKNOWN.
GMP facility production hold
Phase I Malignant Glioma trial by University of Florida. Stop reason: OPERATIONAL.
due to lack of accrual/feasibility to complete accrual due to competing trials
Phase I Acute Myeloid Leukemia trial by University of Florida. Stop reason: OPERATIONAL.
Seeking additional funding sources
Phase I Hepatocellular Carcinoma trial by University of Florida. Stop reason: OPERATIONAL.
funding terminated
Phase I Diffuse Intrinsic Pontine Glioma (DIPG) trial by University of Florida. Stop reason: OPERATIONAL.
Not feasible to accrue due to competing studies
Phase I Glioblastoma trial by University of Florida. Stop reason: OTHER/UNKNOWN.
Terminated by mutual agreement by sponsor and institution.
Phase II Metastatic Colorectal Cancer trial by University of Florida. Stop reason: OPERATIONAL.
slow accrual
Phase II Cutaneous Squamous Cell Carcinoma trial by University of Florida. Stop reason: OTHER/UNKNOWN.
Study not moving forward due to upcoming PI departure
Phase II Acute Myeloid Leukemia trial by University of Florida. Stop reason: OTHER/UNKNOWN.
Study disapproved by internal scientific review committee on re-review; study will no longer move forward
Phase I Melanoma Metastatic in the Brain trial by University of Florida. Stop reason: OPERATIONAL.
uncertain study staffing
Early Phase I Aneurysmal Subarachnoid Hemorrhage trial by University of Florida. Stop reason: OTHER/UNKNOWN.
Lost support from the drug manufacturer
Phase IV TMJ trial by University of Florida. Stop reason: OPERATIONAL.
Could not recruit participants due to their refusal to be randomized in the study.
Phase II Acute Myeloid Leukemia trial by University of Florida. Stop reason: OPERATIONAL.
PI decision to close study early due to limited data due to accrual goal not being met
Phase IV Alcohol Use Disorder trial by University of Florida. Stop reason: OTHER/UNKNOWN.
This was an internally-funded pilot and priority had to be given to grant-funded projects.
Phase IV Catamenial Epilepsy trial by University of Florida. Stop reason: OPERATIONAL.
Poor enrollment
Phase II Acute Respiratory Distress trial by University of Florida. Stop reason: REGULATORY.
Study never started due to need for additional preclinical work requested by FDA\>
Phase I Hypertension trial by University of Florida. Stop reason: OPERATIONAL.
This study was never started and no participants were enrolled.
Phase IV Pneumonia trial by University of Florida. Stop reason: OPERATIONAL.
Low recruitment.
Early Phase I Alcohol Use Disorder (AUD) trial by University of Florida. Stop reason: OPERATIONAL.
The COVID-19 outbreak began, precluding further participant recruitment for this protocol, which could only be conducted in-person. A decision was made that ample data was available to end data collection earlier than anticipated.
Phase I Leukemia trial by University of Florida. Stop reason: OPERATIONAL.
slow enrollment
Phase II Glioblastoma Multiforme trial by University of Florida. Stop reason: OPERATIONAL.
stagnant enrollment
Phase IV Pain Reduction trial by University of Florida. Stop reason: OTHER/UNKNOWN.
Per study team, the study will not proceed
Phase IV Pulmonary Hypertension trial by University of Florida. Stop reason: OPERATIONAL.
Study funding ended before recruitment completed.
Phase II Inflammation trial by University of Florida. Stop reason: OTHER/UNKNOWN.
Potential participants had concerns about taking the study drug (methotrexate).
Phase III COVID-19 trial by University of Florida. Stop reason: OPERATIONAL.
No patients enrolled and funding withdrawn
Phase II Patent Ductus Arteriosus trial by University of Florida. Stop reason: OPERATIONAL.
Unable to obtain funding to support this project
Phase IV Osteoarthritis of the Glenohumeral Joint trial by University of Florida. Stop reason: OTHER/UNKNOWN.
The physician in charge is leaving the University of Florida
Phase II Pancreatic Cancer trial by University of Florida. Stop reason: OPERATIONAL.
insufficient time to accrue sufficient subjects before end of funding
Phase I Inflammation trial by University of Florida. Stop reason: OPERATIONAL.
This study was halted prematurely due to the COVID-19 pandemic, resulting in the inability to enroll participants. Funding for this project has also ended.
Phase IV Pain, Postoperative trial by University of Florida. Stop reason: OTHER/UNKNOWN.
Withdrawn from the IRB
Phase I Leukemia, Myeloid trial by University of Florida. Stop reason: OPERATIONAL.
Slow accrual
Phase IV Smoking Cessation trial by University of Florida. Stop reason: OTHER/UNKNOWN.
PI is relocating to another institution.
Phase I Kava on the Metabolism of Nicotine and NNK trial by University of Florida. Stop reason: OTHER/UNKNOWN.
Terms could not be met with the FDA.
Phase I Breast Cancer trial by University of Florida. Stop reason: OTHER/UNKNOWN.
institutional conflict of interest
Phase IV Persistent Fetal Circulation Syndrome trial by University of Florida. Stop reason: OPERATIONAL.
Difficult to identify subjects who meet enrollment criteria.
Phase IV Pregnancy trial by University of Florida. Stop reason: REGULATORY.
Due to FDA constraints on the off label use of the medications we will not be able to conduct this evaluation.
Phase I Non-Small Cell Lung Cancer trial by University of Florida. Stop reason: OPERATIONAL.
Slow accrual
Early Phase I Anesthesia, Local trial by University of Florida. Stop reason: OPERATIONAL.
funding not obtained
Phase III Recurrent Nasopharynx Carcinoma trial by University of Florida. Stop reason: OPERATIONAL.
This is a rare disease, and enrollment was poor.
Phase IV Asthma trial by University of Florida. Stop reason: OPERATIONAL.
insufficient number of participants met the enrollment criteria.
Unknown Myelodysplastic Syndromes trial by University of Florida. Stop reason: OPERATIONAL.
administratively withdrawn
Phase IV Analgesia trial by University of Florida. Stop reason: OTHER/UNKNOWN.
PI is leaving the University of Florida
Phase II Tobacco Use Disorder trial by University of Florida. Stop reason: OTHER/UNKNOWN.
Study was not started and participants were not enrolled
Phase II Kidney Diseases trial by University of Florida. Stop reason: OTHER/UNKNOWN.
Insufficient resources necessary for completion.
Phase II Esophageal Cancer trial by University of Florida. Stop reason: OPERATIONAL.
non-accrual
Phase I Pompe Disease trial by University of Florida. Stop reason: OTHER/UNKNOWN.
Participants not interested in enrolling.
Phase II Socioemotional Aging trial by University of Florida. Stop reason: OPERATIONAL.
Technical issues preventing recruitment.
Phase II Squamous Cell Skin Carcinoma trial by University of Florida. Stop reason: OPERATIONAL.
Poor accrual
Phase II Acute Myeloid Leukemia trial by University of Florida. Stop reason: OPERATIONAL.
Insufficient funding
Early Phase I Pompe Disease trial by University of Florida. Stop reason: EFFICACY/FUTILITY.
The drug was ineffective in improving function in Pompe's disease
Phase I Sepsis trial by University of Florida. Stop reason: OPERATIONAL.
Unable to recruit sufficient number of patients
Phase III Chronic Rhinosinusitis (Diagnosis) trial by University of Florida. Stop reason: OTHER/UNKNOWN.
Withdrawn by sponsor
Phase II Bacterial Pneumonia trial by University of Florida. Stop reason: OPERATIONAL.
NIAID terminated the study due to low subject enrollment
Phase I Leukemia, Myelogenous, Acute trial by University of Florida. Stop reason: OTHER/UNKNOWN.
No stop-reason text available in the compact dataset.
Phase I Myelodysplastic Syndromes trial by University of Florida. Stop reason: OPERATIONAL.
Lack of funding to support clinical trial
Phase I Cholestasis trial by University of Florida. Stop reason: OTHER/UNKNOWN.
No stop-reason text available in the compact dataset.
Phase II Soft Tissue Sarcomas trial by University of Florida. Stop reason: OTHER/UNKNOWN.
No patients accrued since study opened
Phase II Acute Cerebrovascular Accident trial by University of Florida. Stop reason: OTHER/UNKNOWN.
Investigator is leaving the institution.
Phase IV Female Androgenetic Alopecia trial by University of Florida. Stop reason: OPERATIONAL.
PI indicating she was withdrawing her study submission due to lack of funding as of 6/20/2016
Unknown Airway Complication of Anaesthesia trial by University of Florida. Stop reason: OTHER/UNKNOWN.
The PI has relocated and the study has been closed.
Phase II Acute Cerebrovascular Accident trial by University of Florida. Stop reason: OTHER/UNKNOWN.
The PI is leaving the University of Florida.
Phase III Small Cell Lung Cancer trial by University of Florida. Stop reason: OPERATIONAL.
Unable to enroll adequate number of participants
Unknown Healthy trial by University of Florida. Stop reason: OPERATIONAL.
Difficulty in obtaining the solution from the compounding pharmacies caused a two year delay in start-up; the funding ended prior to study completion.