Preclassified stop reasons
Review efficacy, futility, safety, operational, funding, regulatory, and unknown signals.
Clinical trial failure database
Find why clinical trials stop
Search terminated, suspended, and withdrawn studies by sponsor, phase, disease area, drug, and likely stop reason.
23,617stopped-trial records
1,821likely biological signals
2026-08-14latest dataset update
| NCT ID | Sponsor / phase | Status | Stop reason and source language |
|---|---|---|---|
| NCT06013371 | Icahn School of Medicine at Mount SinaiPhase II | TERMINATED | Efficacy / futilityThe study ended early after interim analysis. |
| NCT05401058 | RenJi HospitalUnknown | TERMINATED | SafetyThe trial was terminated on the independent DSMB's recommendation after an interim analysis showed no evidence of ben... |
| NCT06694454 | National Cancer Institute (NCI)Phase I | SUSPENDED | OperationalPlaced on voluntary hold to new recruitment pending modification to combination monoclonal antibody treatment. |
| NCT05652504 | National Institute of Allergy and Infectious Diseases (NIAID)Phase I | SUSPENDED | RegulatoryThe study remains on hold due to a funding issue after it's been lifted by the FDA. |
What it does
Search. Filter. Verify.
Fewer explanations on the homepage, more direct paths into the data.
One-click to evidence
Open the NCT page, stop language, and source-linked trial detail from any record.
Sponsor and pattern views
Compare repeated stops by sponsor, phase, disease area, and reason bucket.
Deep dives
Useful entry points
Data-led pages for the most common research questions.
Strongest angleTerminated does not always mean failedUse stopped-trial status carefully before calling something a drug failure.Read insight →GuideWhy trials failCompare efficacy, safety, enrollment, funding, and operational causes.Open guide →Therapeutic areaOncology trial stopsFocus on cancer trial terminations, futility, and safety patterns.Open guide →Top listTop oncology failure signalsRank oncology drugs and interventions by stopped-trial evidence.Open ranking →Sponsor rankingPharma companies by failure shareCompare likely biological stop signals against sponsor stopped-trial volume.Open ranking →
See all guides →Trust and method
Medical-data shortcuts still need source discipline
The database is derived from public ClinicalTrials.gov records. Classifications are screening signals for analysis - not clinical guidance, investment advice, or a substitute for the primary source record.
- Dataset version
- 2026-08-14
- Stopped records
- 23,617
- Likely biological signals
- 1,821
- Primary source
- ClinicalTrials.gov API v2
- Built by
- Clinical Trial Failures