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Fred Hutchinson Cancer Center clinical trial failures
Review 66 stopped clinical trials from Fred Hutchinson Cancer Center, including disease areas, phases, and classified stop reasons.
This page groups real ClinicalTrials.gov-derived stopped trial records. The strongest added signal is the stop-reason classification: 3 of these records are likely biological failure signals, while the rest may reflect operational, strategic, regulatory, funding, enrollment, or unclear stop reasons.
Dominant stop reasons
- OPERATIONAL
- 48
- OTHER/UNKNOWN
- 14
- EFFICACY/FUTILITY
- 2
- REGULATORY
- 1
- SAFETY
- 1
Notable sponsors
- Fred Hutchinson Cancer Center
- 66
Related phases
- Phase I
- 37
- Phase II
- 23
- Phase IV
- 2
- Unknown
- 2
- Early Phase I
- 1
Crawlable stopped-trial records
Open ExploreShowing up to 66 representative records from this slice. Each link opens the trial detail page with source attribution and stop-reason context.
Phase I Metastatic Pancreatic Ductal Adenocarcinoma trial by Fred Hutchinson Cancer Center. Stop reason: OPERATIONAL.
Study terminated due to end of funding.
Phase II Acute Lymphoblastic Leukemia trial by Fred Hutchinson Cancer Center. Stop reason: SAFETY.
Study was terminated prior to enrolling protocol target accrual goal due to declining accrual and Data Safety Monitoring Board recommendations.
Phase III Acute Respiratory Failure trial by Fred Hutchinson Cancer Center. Stop reason: EFFICACY/FUTILITY.
due to increased mortality and futility analyses
Phase I Prostate Carcinoma trial by Fred Hutchinson Cancer Center. Stop reason: OPERATIONAL.
Study closed before opening to accrual
Phase I Other Skin trial by Fred Hutchinson Cancer Center. Stop reason: OPERATIONAL.
Terminated due to insufficient funding
Phase I COVID-19 Infection trial by Fred Hutchinson Cancer Center. Stop reason: REGULATORY.
Terminated due to FDA withdrawal of the emergency use authorization (EUA) for sotrovimab
Phase II Acute Erythroid Leukemia trial by Fred Hutchinson Cancer Center. Stop reason: OPERATIONAL.
The federal funding period ended. The study was originally intended to be multi-site but was only conducted at the lead site. Due to the rarity of the subject population \& smaller # of enrolling sites, we were not able to reach accrual goals.
Phase I Hematopoietic and Lymphoid Cell Neoplasm trial by Fred Hutchinson Cancer Center. Stop reason: OPERATIONAL.
The study was closed to accrual according to the Fred Hutch/University of Washington/Seattle Children's Consortium low accrual institutional policy.
Phase I Chronic Graft Versus Host Disease trial by Fred Hutchinson Cancer Center. Stop reason: OPERATIONAL.
Study closed to accrual early due to side effects of study drug.
Phase I Recurrent B Acute Lymphoblastic Leukemia trial by Fred Hutchinson Cancer Center. Stop reason: OPERATIONAL.
Study closed before opening to accrual, no participants enrolled
Phase I AIDS-Related Kaposi Sarcoma trial by Fred Hutchinson Cancer Center. Stop reason: OPERATIONAL.
Terminated due to end of funding
Phase II Acute Myeloid Leukemia trial by Fred Hutchinson Cancer Center. Stop reason: OPERATIONAL.
Terminated due to low accrual
Phase I Fanconi Anemia trial by Fred Hutchinson Cancer Center. Stop reason: OPERATIONAL.
Study ended early due to end of funding.
Phase I Metastatic Leiomyosarcoma trial by Fred Hutchinson Cancer Center. Stop reason: OPERATIONAL.
The study was terminated early with 27 out of 28 planned subjects enrolled. This decision was multifactorial, including slow enrollment in the last remaining cohort and a lack of evidence of clinical benefit.
Phase I Recurrent Adult Acute Lymphoblastic Leukemia trial by Fred Hutchinson Cancer Center. Stop reason: OPERATIONAL.
Terminated due to slow enrollment and end of funding
Phase IV High Grade Anal Canal Intraepithelial Neoplasia trial by Fred Hutchinson Cancer Center. Stop reason: EFFICACY/FUTILITY.
The study was terminated early due to futility.
Phase I Plasma Cell Myeloma trial by Fred Hutchinson Cancer Center. Stop reason: OPERATIONAL.
NIH terminated funding. Study was closed before any participants were enrolled.
Phase I Recurrent Plasma Cell Myeloma trial by Fred Hutchinson Cancer Center. Stop reason: OPERATIONAL.
Closed per SRC Low Accrual Policy
Phase I Burkitt Lymphoma trial by Fred Hutchinson Cancer Center. Stop reason: OPERATIONAL.
Closed per SRC Low Accrual Policy
Phase I Anatomic Stage IV Breast Cancer AJCC v8 trial by Fred Hutchinson Cancer Center. Stop reason: OPERATIONAL.
Terminated due to slow accrual.
Phase I Acute Myeloid Leukemia Arising From Previous Myelodysplastic Syndrome trial by Fred Hutchinson Cancer Center. Stop reason: OPERATIONAL.
Terminated due to loss of funding
Phase II Acute Biphenotypic Leukemia trial by Fred Hutchinson Cancer Center. Stop reason: OPERATIONAL.
The study experienced lower accrual rates after the onset of COVID. Upon review of the collected data it was deemed that an adequate amount of subjects has been enrolled to date to assess study aims.
Phase I Recurrent Diffuse Large B-Cell Lymphoma trial by Fred Hutchinson Cancer Center. Stop reason: OPERATIONAL.
PI left institution and funding sponsor closed study. Study did not open to accrual, and no participants were enrolled.
Phase II Adult Acute Myeloid Leukemia With 11q23 (MLL) Abnormalities trial by Fred Hutchinson Cancer Center. Stop reason: OPERATIONAL.
Funding ended before target accrual was reached; participants are no longer being examined or receiving intervention.
Phase I Recurrent Melanoma trial by Fred Hutchinson Cancer Center. Stop reason: OPERATIONAL.
ONTAK has been pulled off the market for further testing. Subsequently, EISAI will no longer be supporting clinical trials that utilize this drug.
Phase I Hematopoietic and Lymphoid Cell Neoplasm trial by Fred Hutchinson Cancer Center. Stop reason: OPERATIONAL.
Terminated due to slow accruals.
Phase I Diffuse Large B-Cell Lymphoma, Not Otherwise Specified trial by Fred Hutchinson Cancer Center. Stop reason: OPERATIONAL.
Terminated due to slow accrual.
Phase I Recurrent Adult Acute Myeloid Leukemia trial by Fred Hutchinson Cancer Center. Stop reason: OPERATIONAL.
Terminated due to slow accrual.
Phase I Glioblastoma trial by Fred Hutchinson Cancer Center. Stop reason: OPERATIONAL.
Terminated due to loss in funding.
Phase I Metastatic Leiomyosarcoma trial by Fred Hutchinson Cancer Center. Stop reason: OTHER/UNKNOWN.
Terminated due to PI leaving institution
Phase I Merkel Cell Polyomavirus Infection trial by Fred Hutchinson Cancer Center. Stop reason: OPERATIONAL.
Terminated due to loss in funding
Phase I Acute Myeloid Leukemia trial by Fred Hutchinson Cancer Center. Stop reason: OPERATIONAL.
Terminated due to funding difficulties
Phase I Advanced Pleural Malignant Mesothelioma trial by Fred Hutchinson Cancer Center. Stop reason: OPERATIONAL.
Terminated due to loss of funding
Phase II Post-Transplant Lymphoproliferative Disorder trial by Fred Hutchinson Cancer Center. Stop reason: OPERATIONAL.
Terminated due to insufficient funding
Phase II Acute Lymphoblastic Leukemia in Remission trial by Fred Hutchinson Cancer Center. Stop reason: OPERATIONAL.
Insufficient funding
Phase I Adult Nasal Type Extranodal NK/T-cell Lymphoma trial by Fred Hutchinson Cancer Center. Stop reason: OPERATIONAL.
Terminated due to low accrual.
Phase II Acute Myeloid Leukemia trial by Fred Hutchinson Cancer Center. Stop reason: OTHER/UNKNOWN.
PI recommended closure
Phase II Immunodeficiency Syndrome trial by Fred Hutchinson Cancer Center. Stop reason: OPERATIONAL.
Low accrual
Phase I Burkitt Lymphoma trial by Fred Hutchinson Cancer Center. Stop reason: OPERATIONAL.
Closed early due to lack of funding
Phase II Graft Versus Host Disease trial by Fred Hutchinson Cancer Center. Stop reason: OTHER/UNKNOWN.
Did not reach one of the primary endpoints of decreased total acute GVHD
Phase I Acute Bilineal Leukemia trial by Fred Hutchinson Cancer Center. Stop reason: OPERATIONAL.
Insufficient funding
Phase II Anemia trial by Fred Hutchinson Cancer Center. Stop reason: OPERATIONAL.
Terminated due to low accrual
Phase II Crohn Disease trial by Fred Hutchinson Cancer Center. Stop reason: OPERATIONAL.
Annual accrual goal not met
Phase II Acute Biphenotypic Leukemia trial by Fred Hutchinson Cancer Center. Stop reason: OPERATIONAL.
Terminated because of slow recruitment and lack of funding support
Phase II Myxoid Liposarcoma trial by Fred Hutchinson Cancer Center. Stop reason: OPERATIONAL.
Administrative
Early Phase I Myxoid Liposarcoma trial by Fred Hutchinson Cancer Center. Stop reason: OTHER/UNKNOWN.
Enough samples were collected for data analysis.
Phase I AIDS-Related Hodgkin Lymphoma trial by Fred Hutchinson Cancer Center. Stop reason: OPERATIONAL.
Administratively closed prior to subject enrollment
Phase IV HER2/Neu Negative trial by Fred Hutchinson Cancer Center. Stop reason: OPERATIONAL.
Administrative closure based on sponsor recommendation, prior to subject enrollment
Phase I Human Immunodeficiency Virus 1 Positive trial by Fred Hutchinson Cancer Center. Stop reason: OPERATIONAL.
Administrative closure prior to any enrollments
Phase II Prolymphocytic Leukemia trial by Fred Hutchinson Cancer Center. Stop reason: OPERATIONAL.
Low enrollment
Phase II Adult Nasal Type Extranodal NK/T-cell Lymphoma trial by Fred Hutchinson Cancer Center. Stop reason: OPERATIONAL.
Low accrual
Phase I Adult Acute Megakaryoblastic Leukemia (M7) trial by Fred Hutchinson Cancer Center. Stop reason: OTHER/UNKNOWN.
No stop-reason text available in the compact dataset.
Unknown Accelerated Phase Chronic Myelogenous Leukemia trial by Fred Hutchinson Cancer Center. Stop reason: OPERATIONAL.
Funding withdrawal
Phase II Leukemia trial by Fred Hutchinson Cancer Center. Stop reason: OTHER/UNKNOWN.
A new protocol was developed to replace this protocol in 2008, with removal of ATG and extension of MMF duration.
Phase II Adult Acute Megakaryoblastic Leukemia (M7) trial by Fred Hutchinson Cancer Center. Stop reason: OTHER/UNKNOWN.
No stop-reason text available in the compact dataset.
Phase II Graft Versus Host Disease trial by Fred Hutchinson Cancer Center. Stop reason: OTHER/UNKNOWN.
No stop-reason text available in the compact dataset.
Phase I Graft Versus Host Disease trial by Fred Hutchinson Cancer Center. Stop reason: OPERATIONAL.
Low accrual
Phase I Recurrent Merkel Cell Carcinoma trial by Fred Hutchinson Cancer Center. Stop reason: OPERATIONAL.
A Phase I/II study (NCT01758458) is now recruiting
Phase II Acute Myeloid Leukemia With Multilineage Dysplasia Following Myelodysplastic Syndrome trial by Fred Hutchinson Cancer Center. Stop reason: OPERATIONAL.
Closed early due to slow enrollment
Phase II Adult Acute Megakaryoblastic Leukemia (M7) trial by Fred Hutchinson Cancer Center. Stop reason: OTHER/UNKNOWN.
The study was terminated early because there were other competing protocols.
Phase I Accelerated Phase Chronic Myelogenous Leukemia trial by Fred Hutchinson Cancer Center. Stop reason: OTHER/UNKNOWN.
No stop-reason text available in the compact dataset.
Phase II Graft Versus Host Disease trial by Fred Hutchinson Cancer Center. Stop reason: OPERATIONAL.
Study never opened due to lack of funds.
Phase I Adult Synovial Sarcoma trial by Fred Hutchinson Cancer Center. Stop reason: OTHER/UNKNOWN.
No stop-reason text available in the compact dataset.
Unknown Adult Nasal Type Extranodal NK/T-cell Lymphoma trial by Fred Hutchinson Cancer Center. Stop reason: OTHER/UNKNOWN.
No stop-reason text available in the compact dataset.
Phase II Leukemia trial by Fred Hutchinson Cancer Center. Stop reason: OTHER/UNKNOWN.
No patient enrolled on study. Did not get patients in timely fashion. All referrals for study when assessed were not eligible.
Phase I Graft Versus Host Disease trial by Fred Hutchinson Cancer Center. Stop reason: OTHER/UNKNOWN.
No stop-reason text available in the compact dataset.