Trial

NCT04374136

A Phase 3 Study to Evaluate Efficacy and Safety of AL001 in Frontotemporal Dementia (INFRONT-3)
Phase IIITERMINATEDEFFICACY/FUTILITYConfidence: HIGH
Sponsor
Alector Inc.
Collaborators
GlaxoSmithKline
Condition
Frontotemporal Dementia
Intervention
AL001
Why stopped
The trial did not meet the clinical co-primary endpoint of slowing FTD-GRN progression, as measured by the Clinical Dementia Rating® plus National Alzheimer's Coordinating Center Frontotemporal Lobar Degeneration Sum of Boxes (CDR® plus NACC FTLD-SB)
Provenance
Dataset: 2026-07-02 • Source: ClinicalTrials.gov API v2 • Last update: 2026-01-21