Trial

NCT03996473

Study to Test the Safety and How Radium-223 Dichloride an Alpha Particle-emitting Radioactive Agent Works in Combination With Pembrolizumab an Immune Checkpoint Inhibitor in Patients With Stage IV Non-small Cell Lung Cancer With Bone Metastases
Phase ITERMINATEDOPERATIONALConfidence: HIGH
Sponsor
Bayer
Collaborators
Merck Sharp & Dohme LLC
Condition
Carcinoma, Non-Small-Cell Lung
Intervention
Radium-223 dichloride (Xofigo, BAY 88-8223)
Why stopped
LPLV reached on 30Jan2023. Study was closed early for feasibility reasons related to enrollment of first line IO naïve patients. Safety data is consistent with the known safety profile of both drugs and no new safety issues have been observed
Provenance
Dataset: 2026-07-02 • Source: ClinicalTrials.gov API v2 • Last update: 2024-10-10