Trial
NCT03866187
Safety, Efficacy, Immunogenicity Study of GSK Biologicals' HBV Viral Vector and Adjuvanted Proteins Vaccine (GSK3528869A) in Adult Patients With Chronic Hepatitis B Infection
Phase ITERMINATEDEFFICACY/FUTILITYConfidence: MEDIUM
Sponsor
GlaxoSmithKline
Collaborators
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Condition
Hepatitis B, Chronic
Intervention
ChAd155-hIi-HBV low dose formulation
Why stopped
Following the primary phase (24 weeks post last vaccination) the predefined efficacy endpoint was not met. Noting the lack of efficacy and with the objective to prioritize participants' safety GSK has decided on the early termination of the study.
Provenance
Dataset: 2026-07-02 • Source: ClinicalTrials.gov API v2 • Last update: 2026-02-20