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Vanderbilt University Medical Center clinical trial failures
Review 50 stopped clinical trials from Vanderbilt University Medical Center, including disease areas, phases, and classified stop reasons.
This page groups real ClinicalTrials.gov-derived stopped trial records. The strongest added signal is the stop-reason classification: 1 of these records are likely biological failure signals, while the rest may reflect operational, strategic, regulatory, funding, enrollment, or unclear stop reasons.
Dominant stop reasons
- OPERATIONAL
- 34
- OTHER/UNKNOWN
- 15
- SAFETY
- 1
Notable sponsors
- Vanderbilt University Medical Center
- 50
Related phases
- Phase IV
- 19
- Phase II
- 11
- Phase I
- 10
- Early Phase I
- 4
- Phase III
- 3
Crawlable stopped-trial records
Open ExploreShowing up to 50 representative records from this slice. Each link opens the trial detail page with source attribution and stop-reason context.
Early Phase I Vestibular Migraine trial by Vanderbilt University Medical Center. Stop reason: OPERATIONAL.
Unable to gain interest among colleagues to help recruit participants.
Phase IV Edema trial by Vanderbilt University Medical Center. Stop reason: OPERATIONAL.
Study was never started
Phase IV Hypertension trial by Vanderbilt University Medical Center. Stop reason: OTHER/UNKNOWN.
An alternative study was developed to replace this study.
Phase II HIV/AIDS trial by Vanderbilt University Medical Center. Stop reason: SAFETY.
DSMB recommendations, laboratory quality control (QC) issues. All lab Q/C issues addressed; DSMB approved study re-opening, but due to length of time required to address lab QC issues, insufficient follow-up time was available to complete study.
Phase III Aneurysmal Subarachnoid Hemorrhage trial by Vanderbilt University Medical Center. Stop reason: OTHER/UNKNOWN.
No stop-reason text available in the compact dataset.
Phase II Crohn's Disease trial by Vanderbilt University Medical Center. Stop reason: OPERATIONAL.
Low accrual and subject engagement
Phase III Post-Acute COVID-19 Syndrome trial by Vanderbilt University Medical Center. Stop reason: OTHER/UNKNOWN.
This submission for the pilot study has been withdrawn as the full trial opened under a different NCT number before participants enrolled in the pilot.
Phase II Asthma trial by Vanderbilt University Medical Center. Stop reason: OTHER/UNKNOWN.
Unfunded
Phase I Orthostatic Intolerance trial by Vanderbilt University Medical Center. Stop reason: OPERATIONAL.
Due to COVID-19 pandemic, recruitment was stopped. All the weight loss surgeries were stopped.. Weight Loss clinic (VWL) was closed for IN person visits. We could not recruit any participant for Non surgical weight loss category.
Phase IV Sacro-Iliac Spondylosis trial by Vanderbilt University Medical Center. Stop reason: OPERATIONAL.
recruitment and staffing
Phase IV Multiple Sclerosis trial by Vanderbilt University Medical Center. Stop reason: OTHER/UNKNOWN.
Sponsor declined further support
Phase II Osteoarthritis, Knee trial by Vanderbilt University Medical Center. Stop reason: OPERATIONAL.
Funding for study equipment
Phase IV Opioid Use trial by Vanderbilt University Medical Center. Stop reason: OTHER/UNKNOWN.
Limitations of the prospective study design revealed that a retrospective study design would be better suited.
Phase II Head and Neck Cancer trial by Vanderbilt University Medical Center. Stop reason: OPERATIONAL.
Issues with funding
Phase IV Elbow Fracture trial by Vanderbilt University Medical Center. Stop reason: OTHER/UNKNOWN.
Switched to observational study type.
Phase I COVID-19 Infection trial by Vanderbilt University Medical Center. Stop reason: OPERATIONAL.
Recruitment issues after COVID-19 abated; not enough hypoxic patients to meet criteria.
Phase IV Overactive Bladder trial by Vanderbilt University Medical Center. Stop reason: OPERATIONAL.
Early termination due to recruitment and follow-up challenges during the pandemic
Phase I Obese trial by Vanderbilt University Medical Center. Stop reason: OPERATIONAL.
Sponsor Decision.
Phase II Community-acquired Pneumonia trial by Vanderbilt University Medical Center. Stop reason: OPERATIONAL.
Limited enrollment due to the COVID-19 pandemic. Sponsor withdrew funding.
Phase II Hypertrophic Scar trial by Vanderbilt University Medical Center. Stop reason: OTHER/UNKNOWN.
Intervention causing discomfort to participants
Phase II Clostridium Difficile trial by Vanderbilt University Medical Center. Stop reason: OPERATIONAL.
Low enrollment
Phase III Tachycardia, Ventricular trial by Vanderbilt University Medical Center. Stop reason: OPERATIONAL.
Study was terminated due to low accrual
Phase IV Critical Illness trial by Vanderbilt University Medical Center. Stop reason: OPERATIONAL.
No enrollment, IRB closed
Unknown Schizophrenia trial by Vanderbilt University Medical Center. Stop reason: OPERATIONAL.
Recruitment challenges due to Covid19.
Early Phase I Transfusion Related Complication trial by Vanderbilt University Medical Center. Stop reason: OPERATIONAL.
Study was never started
Phase IV Asthma trial by Vanderbilt University Medical Center. Stop reason: OPERATIONAL.
Dr. Arnold assisted in designing and initiating study for a pharmacology PhD candidate. The candidate left the institution and study enrollment was terminated.
Phase I COPD trial by Vanderbilt University Medical Center. Stop reason: OPERATIONAL.
Funding has ended and unable to recruit due to COVID 19
Phase II Schizophrenia trial by Vanderbilt University Medical Center. Stop reason: OTHER/UNKNOWN.
Study was redesigned and submitted as a new protocol (NCT04559529).
Phase I Insulin Resistance trial by Vanderbilt University Medical Center. Stop reason: OTHER/UNKNOWN.
The investigators decided not to perform the study. No participants have been enrolled.
Phase I Cognitive Impairment trial by Vanderbilt University Medical Center. Stop reason: OTHER/UNKNOWN.
Further development has been outlicensed to Acadia Pharmaceuticals
Phase I Glucose Intolerance trial by Vanderbilt University Medical Center. Stop reason: OPERATIONAL.
Difficulty in participant recruitment
Early Phase I Autonomic Nervous System Disorders trial by Vanderbilt University Medical Center. Stop reason: OPERATIONAL.
Difficulty recruiting
Unknown Asthma trial by Vanderbilt University Medical Center. Stop reason: OPERATIONAL.
The trainee for whom I designed the study did not begin enrollment and has left our institution.
Phase I Ischemia trial by Vanderbilt University Medical Center. Stop reason: OPERATIONAL.
Study was terminated because funding could not be secured
Phase IV Cesarean Delivery trial by Vanderbilt University Medical Center. Stop reason: OPERATIONAL.
Lack of enrollment
Phase IV Cervical Radiculopathy trial by Vanderbilt University Medical Center. Stop reason: OPERATIONAL.
funding
Phase IV Mastectomy trial by Vanderbilt University Medical Center. Stop reason: OTHER/UNKNOWN.
Extensive protocol revisions initiated.
Phase I Insulin Sensitivity trial by Vanderbilt University Medical Center. Stop reason: OPERATIONAL.
No fundings
Phase IV Septic Shock trial by Vanderbilt University Medical Center. Stop reason: OPERATIONAL.
Slow enrollment; Lack of support and equipoise
Unknown Surgical Site Infection trial by Vanderbilt University Medical Center. Stop reason: OPERATIONAL.
unable to enroll any participants
Phase IV Adenomyosis trial by Vanderbilt University Medical Center. Stop reason: OTHER/UNKNOWN.
IND issues
Phase II Heart Failure NYHA Class I trial by Vanderbilt University Medical Center. Stop reason: OTHER/UNKNOWN.
Study is being redesigned and submitted as a new study.
Phase IV Dermatitis Herpetiformis trial by Vanderbilt University Medical Center. Stop reason: OPERATIONAL.
poor enrollment and lack of funding
Early Phase I Obesity trial by Vanderbilt University Medical Center. Stop reason: OTHER/UNKNOWN.
Preliminary data run on rat samples showed that this study question and design would not produce conclusive results. The PI decided not to carry out the study.
Phase IV Subarachnoid Hemorrhage trial by Vanderbilt University Medical Center. Stop reason: OPERATIONAL.
no funding
Phase I Delirium trial by Vanderbilt University Medical Center. Stop reason: OPERATIONAL.
poor recruitment
Phase IV Sezary Syndrome trial by Vanderbilt University Medical Center. Stop reason: OPERATIONAL.
Difficulty recruiting.
Phase IV Treatment Resistant Depression trial by Vanderbilt University Medical Center. Stop reason: OPERATIONAL.
failed recruitment efforts
Phase IV ACE Inhibitor-associated Angioedema trial by Vanderbilt University Medical Center. Stop reason: OPERATIONAL.
DSMC recommended discontinuation for futility and feasibility
Phase II Hypertension trial by Vanderbilt University Medical Center. Stop reason: OPERATIONAL.
failure to recruit