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University of Utah clinical trial failures
Review 94 stopped clinical trials from University of Utah, including disease areas, phases, and classified stop reasons.
This page groups real ClinicalTrials.gov-derived stopped trial records. The strongest added signal is the stop-reason classification: 1 of these records are likely biological failure signals, while the rest may reflect operational, strategic, regulatory, funding, enrollment, or unclear stop reasons.
Dominant stop reasons
- OPERATIONAL
- 61
- OTHER/UNKNOWN
- 31
- EFFICACY/FUTILITY
- 1
- REGULATORY
- 1
Notable sponsors
- University of Utah
- 94
Related phases
- Phase I
- 32
- Phase II
- 30
- Phase IV
- 12
- Early Phase I
- 8
- Unknown
- 8
Crawlable stopped-trial records
Open ExploreShowing up to 94 representative records from this slice. Each link opens the trial detail page with source attribution and stop-reason context.
Phase I Borderline Resectable Pancreatic Adenocarcinoma trial by University of Utah. Stop reason: OPERATIONAL.
Closed due to slow accrual
Phase I Metastatic Castration-resistant Prostate Cancer trial by University of Utah. Stop reason: OTHER/UNKNOWN.
DSMC Safety Analysis
Phase I Pain trial by University of Utah. Stop reason: OTHER/UNKNOWN.
Study is paused while preparing for implementation at IND Sponsor's new institution
Phase II Primary Myelofibrosis trial by University of Utah. Stop reason: OPERATIONAL.
PI and Sponsor decision. Accrual was low and there was sufficient data to detect a response.
Phase I Metastatic Pancreatic Carcinoma trial by University of Utah. Stop reason: OPERATIONAL.
Lack of Funding
Phase I B-cell Non Hodgkin Lymphoma trial by University of Utah. Stop reason: OTHER/UNKNOWN.
Drug Unavailable
Phase II Prostate Adenocarcinoma trial by University of Utah. Stop reason: OPERATIONAL.
Drug Supply Issue
Early Phase I Cardiovascular Diseases trial by University of Utah. Stop reason: OPERATIONAL.
COVID initially delayed plans to begin recruitment of subjects. Subsequently, the departure of a clinical investigator and loss of access to equipment and study subject population resulted in study termination before any subjects were enrolled.
Phase I Kidney Transplantation trial by University of Utah. Stop reason: OPERATIONAL.
lack of funding
Phase III Breast Cancer trial by University of Utah. Stop reason: OTHER/UNKNOWN.
The study team will no longer be enrolling patients for this research.
Phase I Chronic Lymphocytic Leukemia trial by University of Utah. Stop reason: OTHER/UNKNOWN.
This study was terminated due to sponsor de-activation of all programs associated with RP-3500 (camonsertib).
Phase II Invasive Lobular Breast Carcinoma trial by University of Utah. Stop reason: OTHER/UNKNOWN.
PI is leaving the institution.
Phase II Colorectal Cancer trial by University of Utah. Stop reason: OPERATIONAL.
PI Determination - Slow recruitment, funding concerns, poor response to treatment
Early Phase I Gastrointestinal Cancer trial by University of Utah. Stop reason: OPERATIONAL.
Challenges with feasibility
Phase II Clinical Stage III HPV-Mediated (p16-Positive) Oropharyngeal Carcinoma AJCC v8 trial by University of Utah. Stop reason: OPERATIONAL.
Insufficient funding
Phase I Brain Tumor trial by University of Utah. Stop reason: OPERATIONAL.
poor accrual and PI retired
Phase II Breast Cancer trial by University of Utah. Stop reason: OPERATIONAL.
Enrollment challenges
Phase II Headache trial by University of Utah. Stop reason: OPERATIONAL.
Due to COVID-19 and both co-investigators have departed from the institution, we weren't able to enroll participants. Additionally, funding has lapse
Early Phase I Estrogen Receptor Positive Breast Cancer trial by University of Utah. Stop reason: OPERATIONAL.
It was not feasible to perform FES PET/CT
Phase I Brain Cancer trial by University of Utah. Stop reason: OTHER/UNKNOWN.
PI retired, study closed
Phase II Peutz-Jeghers Syndrome trial by University of Utah. Stop reason: OPERATIONAL.
The study was ended early due to low enrollment.
Phase IV Major Depressive Disorder trial by University of Utah. Stop reason: OTHER/UNKNOWN.
No referral from diabetes clinic.
Early Phase I Infant,Premature trial by University of Utah. Stop reason: OPERATIONAL.
The study stopped enrollment prior to the initially projected 18 subjects per phase due to lack of funding to continue to recertify the drug and because an adequate number of subjects were enrolled for each phase to analyze pharmacokinetics.
Phase I Wounds and Injuries trial by University of Utah. Stop reason: OPERATIONAL.
Enrollment was halted prematurely after enrolling one participant due to difficulty finding eligible participants.
Phase II Prostate Cancer trial by University of Utah. Stop reason: OTHER/UNKNOWN.
New standard of care for study participant population
Phase II Chronic Graft-versus-host-disease trial by University of Utah. Stop reason: OPERATIONAL.
PI left institution
Phase IV Discogenic Pain trial by University of Utah. Stop reason: OPERATIONAL.
Low enrollment
Early Phase I Pain trial by University of Utah. Stop reason: OPERATIONAL.
Adequate enrollment was not reached for this study.
Phase III Major Depressive Disorder trial by University of Utah. Stop reason: OTHER/UNKNOWN.
Institution was unable to manufacture radiotracer that was central to the protocol. Study transferred to another institution.
Phase I Multiple Myeloma trial by University of Utah. Stop reason: OTHER/UNKNOWN.
Closed at PI's Request
Phase IV Erectile Dysfunction trial by University of Utah. Stop reason: OPERATIONAL.
They study lost funding and decided to close the study down.
Phase II Post-Dural Puncture Headache trial by University of Utah. Stop reason: OTHER/UNKNOWN.
Both Study PI's left the institution
Phase IV Cervical Radiculopathy trial by University of Utah. Stop reason: OPERATIONAL.
Not enough cervical interlaminar patients who meet criteria in order to meet recruitment goals.
Phase II Melanoma trial by University of Utah. Stop reason: OTHER/UNKNOWN.
DSMC Recommendation
Phase II Neurofibromatosis Type 1 (NF1) trial by University of Utah. Stop reason: OPERATIONAL.
unable to enroll
Phase II Anemia trial by University of Utah. Stop reason: OPERATIONAL.
Slow accrual
Phase I Cancer trial by University of Utah. Stop reason: OPERATIONAL.
Funding from the NIH ended and not all patients had been accrued
Phase IV Venous Thromboembolism trial by University of Utah. Stop reason: OPERATIONAL.
Funding was not received.
Phase I Colorectal Cancer trial by University of Utah. Stop reason: OPERATIONAL.
PI Decision
Phase II Neuroendocrine Tumors trial by University of Utah. Stop reason: OTHER/UNKNOWN.
Update on clinical development: after discussions with the drug manufacturer, the PI has decided to discontinue the trial.
Phase I Bone Metastases trial by University of Utah. Stop reason: OPERATIONAL.
Enrollment incomplete by the end of the contracted enrollment period
Phase IV Myofascial Pain trial by University of Utah. Stop reason: OPERATIONAL.
Poor enrollment.
Phase I Metastatic Adenocarcinoma trial by University of Utah. Stop reason: OPERATIONAL.
study abandoned for funding issues
Unknown MRI Scans trial by University of Utah. Stop reason: OTHER/UNKNOWN.
MRI perfusion techniques development took longer than expected.
Phase I High Risk Hematologic Malignancies trial by University of Utah. Stop reason: OPERATIONAL.
Trial discontinued prior to starting Phase II portion due to low accrual.
Phase I Advanced Malignancies trial by University of Utah. Stop reason: OPERATIONAL.
Funding source withdrew financial support prior to start of Phase II portion of study
Phase II Castration-Sensitive Prostate Carcinoma trial by University of Utah. Stop reason: OTHER/UNKNOWN.
The trial was closed because the changing standard of care landscape, making this trial not impactful anymore.
Early Phase I Stroke trial by University of Utah. Stop reason: OPERATIONAL.
Funding withdrawn
Phase I Appendicitis trial by University of Utah. Stop reason: OTHER/UNKNOWN.
Lost research support for enrolling patients
Phase III Major Depressive Disorder trial by University of Utah. Stop reason: OTHER/UNKNOWN.
Unable to perform brain imaging
Phase II Treatment Resistant Depression trial by University of Utah. Stop reason: OPERATIONAL.
Change in study design based on phase 1 data collection; patient burden was not feasible
Phase I Hepatocellular Carcinoma trial by University of Utah. Stop reason: OPERATIONAL.
PI decided to terminate due to low/slow accrual
Unknown Secondary Progressive Multiple Sclerosis trial by University of Utah. Stop reason: OPERATIONAL.
Low enrollment/PI relocated. New site couldn't reach agreement with manufacturer
Phase II Type1 Diabetes Mellitus trial by University of Utah. Stop reason: OPERATIONAL.
Slow subject enrollment, unable to complete trial in a timely manner
Unknown Psoriasis trial by University of Utah. Stop reason: OPERATIONAL.
lack of efficacy and lack of funding
Phase I Advanced GI Cancer trial by University of Utah. Stop reason: OTHER/UNKNOWN.
Merck requested to change MK-3475 dosing schedule; PI decided to close instead
Phase II Gulf War Illness trial by University of Utah. Stop reason: OTHER/UNKNOWN.
Original study product (VSL #3) became unavailable; change in study Collaborator and product
Phase IV Chorioamnionitis trial by University of Utah. Stop reason: OPERATIONAL.
Participant enrollment was much more challenging than anticipated.
Phase I Fibromyalgia Pain trial by University of Utah. Stop reason: OPERATIONAL.
The funding ended.
Phase IV Post-traumatic Stress Disorder trial by University of Utah. Stop reason: OPERATIONAL.
Insufficient enrollment
Phase II Glioblastoma Multiforme (GBM) trial by University of Utah. Stop reason: OPERATIONAL.
Unable to get materials from GE, study not proceeding and never opened to accrual
Phase I Acute Lymphoblastic Leukemia trial by University of Utah. Stop reason: OTHER/UNKNOWN.
Termination of Investigator Initiated Studies using Ibrutinib
Phase II Upper GI Cancer trial by University of Utah. Stop reason: OPERATIONAL.
Low Accrual
Phase II Ovarian Cancer trial by University of Utah. Stop reason: OPERATIONAL.
Slow Accrual
Phase II Multiple Myeloma trial by University of Utah. Stop reason: OPERATIONAL.
Slow Accrual
Phase I Pain trial by University of Utah. Stop reason: OTHER/UNKNOWN.
Difficulty enrolling patients
Phase I Cancer trial by University of Utah. Stop reason: OTHER/UNKNOWN.
Data analysis revealed sufficient data for safety and efficacy
Phase I BRAFV600 Mutation trial by University of Utah. Stop reason: OTHER/UNKNOWN.
Competing Trials
Phase I Stages II-III Breast Cancer trial by University of Utah. Stop reason: OPERATIONAL.
Drug Manufacturer withdrew support for studies not in metastatic breast cancer
Phase II Cancer trial by University of Utah. Stop reason: OPERATIONAL.
discontinued due to low enrollment
Phase I Stage III or IV Melanoma trial by University of Utah. Stop reason: OPERATIONAL.
BMS withdrew support and required this trial to stop enrolling; Phase II portion never began, only a Phase I trial.
Phase II Gastrointestinal Stromal Tumors trial by University of Utah. Stop reason: OTHER/UNKNOWN.
PI terminated at the recommendation of DSMC \& IRB
Unknown Erythropoietic Protoporphyria (EPP) trial by University of Utah. Stop reason: EFFICACY/FUTILITY.
Interim analysis demonstrated the treatment was not effective
Phase I Stroke trial by University of Utah. Stop reason: OPERATIONAL.
Recruitment was problematic
Unknown Pain trial by University of Utah. Stop reason: OPERATIONAL.
Study never initiated
Unknown Intracranial Hemorrhage, Traumatic trial by University of Utah. Stop reason: OPERATIONAL.
Lack of enrolment
Phase I KRAS and NRAS Wild-type Colorectal Cancer trial by University of Utah. Stop reason: OPERATIONAL.
Slow accrual
Phase IV Dyslipidemia trial by University of Utah. Stop reason: OPERATIONAL.
Collaborator/corporate sponsor withdrew funding and permission to continue.
Phase IV Major Depressive Disorder trial by University of Utah. Stop reason: OTHER/UNKNOWN.
Study withdrawn from ClinicalTrials.gov.
Phase II Recurrent Pregnancy Loss trial by University of Utah. Stop reason: REGULATORY.
Testing required by FDA for IND approval was too expensive to move forward with conduct of the study.
Phase II Gastroesophageal Reflux trial by University of Utah. Stop reason: OPERATIONAL.
limited recruitment
Phase I Corneal Neovascularization trial by University of Utah. Stop reason: OPERATIONAL.
No participants enrolled
Phase I Cancer trial by University of Utah. Stop reason: OPERATIONAL.
Enrollment was going slowly and needed to be closed.
Phase II Cancer trial by University of Utah. Stop reason: OPERATIONAL.
Lab Staff that was required left the institution, therefore accrual closed prematurely
Unknown Patent Ductus Arteriosus trial by University of Utah. Stop reason: OTHER/UNKNOWN.
Study drug not available
Unknown Pancreatic Ductal Adenocarcinoma trial by University of Utah. Stop reason: OPERATIONAL.
No accrual
Early Phase I Hypertension trial by University of Utah. Stop reason: OTHER/UNKNOWN.
Lack of quality data
Phase III Obesity trial by University of Utah. Stop reason: OPERATIONAL.
Not able meet target enrollment.
Early Phase I Bone Ingrowth trial by University of Utah. Stop reason: OTHER/UNKNOWN.
New clinical finding with Celebrex and cardiac concerns.
Phase IV Hypertriglyceridemia trial by University of Utah. Stop reason: OPERATIONAL.
Withdrawn for administrative reasons.
Phase I Exercise Triggered Asthma trial by University of Utah. Stop reason: OPERATIONAL.
The sponsor decided to terminate the study due to slow enrollment.
Phase IV Atrial Fibrillation trial by University of Utah. Stop reason: OTHER/UNKNOWN.
Not enough patients in time period allotted for study
Phase II Cancer trial by University of Utah. Stop reason: OPERATIONAL.
Low enrollment
Phase II Chronic Idiopathic Urticaria trial by University of Utah. Stop reason: OTHER/UNKNOWN.
Unable to complete agreement with sponsor