Sponsor hub
University of Oxford clinical trial failures
Review 30 stopped clinical trials from University of Oxford, including disease areas, phases, and classified stop reasons.
This page groups real ClinicalTrials.gov-derived stopped trial records. The strongest added signal is the stop-reason classification: 1 of these records are likely biological failure signals, while the rest may reflect operational, strategic, regulatory, funding, enrollment, or unclear stop reasons.
Dominant stop reasons
- OPERATIONAL
- 15
- OTHER/UNKNOWN
- 12
- REGULATORY
- 2
- SAFETY
- 1
Notable sponsors
- University of Oxford
- 30
Related phases
- Phase I
- 18
- Phase II
- 7
- Early Phase I
- 2
- Phase III
- 1
- Phase IV
- 1
Crawlable stopped-trial records
Open ExploreShowing up to 30 representative records from this slice. Each link opens the trial detail page with source attribution and stop-reason context.
Early Phase I Malaria, Vivax trial by University of Oxford. Stop reason: OPERATIONAL.
The study was terminated due to administrative delays in the approval of a substantial amendment to extend the shelf-life of Pvs25-IMX313. Regulatory approval was only received on 11 August 2023, after end of study visits had already been conducted.
Phase I Pharmacokinetic trial by University of Oxford. Stop reason: REGULATORY.
The decision was made due to the expired investigational drug and regulatory changes by the Thai FDA, along with increased importation costs. The research team and investigational drug sponsor agreed to seek approval for early project termination.
Phase I Healthy trial by University of Oxford. Stop reason: OPERATIONAL.
The study was suspended while the researchers secured new funding.
Phase I Ebola Virus Disease trial by University of Oxford. Stop reason: OTHER/UNKNOWN.
Long term follow up will take place in a new clinical trial.
Phase I Intermediate Risk Prostate Cancer trial by University of Oxford. Stop reason: OPERATIONAL.
COVID stopped all trials - and ADVANCE could not restart again after the pandemic
Early Phase I Malaria trial by University of Oxford. Stop reason: OTHER/UNKNOWN.
Significant delays in vaccine adjuvant supply due to an out of specification within the context of the grant timeline. Limited safety and immunological data could be accrued from incomplete regimens.
Phase II Malaria,Falciparum trial by University of Oxford. Stop reason: REGULATORY.
Due to US FDA hold on the challenge agent and funding concerns
Phase I Malaria,Falciparum trial by University of Oxford. Stop reason: OTHER/UNKNOWN.
Due to significant delays in receiving local regulatory approval to extend the shelf-life of the IMP.
Phase I Rabies trial by University of Oxford. Stop reason: OPERATIONAL.
Since acceptable safety, tolerability, and immunogenicity was demonstrated at the highest dose tested (group 3, fully recruited), there was no scientific or ethical justification to recruit more participants into the mid-dose group (group 2).
Phase I Malaria,Falciparum trial by University of Oxford. Stop reason: SAFETY.
Study halted prematurely due to US FDA clinical hold on PfSPZ Challenge
Phase I Alzheimer Disease trial by University of Oxford. Stop reason: OPERATIONAL.
Delayed due to COVID19. Study drug expired before could be used.
Phase I Healthy trial by University of Oxford. Stop reason: OTHER/UNKNOWN.
Study team's decision to withdraw the study.
Phase IV Healthy Lactating Women trial by University of Oxford. Stop reason: OPERATIONAL.
Local EC requested that the arms of study be submitted as separate protocols so they could respond to the different risk of each arm. In response investigators have withdrawn this protocol and begun separate submissions, starting with NCT06191458.
Phase I Pancreatic Ductal Adenocarcinoma trial by University of Oxford. Stop reason: OPERATIONAL.
Lack of recruitment
Unknown P. Falciparum Malaria trial by University of Oxford. Stop reason: OTHER/UNKNOWN.
No adequate malaria patient
Phase I Depression trial by University of Oxford. Stop reason: OPERATIONAL.
Covid-19 pandemic
Phase II Diabetes Mellitus, Type 1 trial by University of Oxford. Stop reason: OPERATIONAL.
Temporary halt due to COVID-19 pandemic
Phase I MERS (Middle East Respiratory Syndrome) trial by University of Oxford. Stop reason: OTHER/UNKNOWN.
The scientific questions proposed remain relevant, but will now be addressed in a larger phase II immunogenicity trial of the ChAdOx1 MERS vaccine given at 2 doses.
Phase II Coronavirus Infection trial by University of Oxford. Stop reason: OTHER/UNKNOWN.
Independent statistical review advice
Phase I Malaria,Falciparum trial by University of Oxford. Stop reason: OPERATIONAL.
Delays caused by Covid-19
Phase I Tuberculosis trial by University of Oxford. Stop reason: OPERATIONAL.
Poor recruitment
Phase I Non-muscle Invasive Bladder Cancer (NMIBC) trial by University of Oxford. Stop reason: OPERATIONAL.
The study failed to recruit within the permitted timeframe
Phase II Osteosarcoma trial by University of Oxford. Stop reason: OPERATIONAL.
Failed to recruit sufficient numbers of patients in the funded period
Phase I Pharmacokinetic trial by University of Oxford. Stop reason: OTHER/UNKNOWN.
No stop-reason text available in the compact dataset.
Phase II Uncomplicated Falciparum Malaria trial by University of Oxford. Stop reason: OTHER/UNKNOWN.
Did not get approval
Phase III Panic Disorder trial by University of Oxford. Stop reason: OTHER/UNKNOWN.
No stop-reason text available in the compact dataset.
Phase I Renal Cancer trial by University of Oxford. Stop reason: OTHER/UNKNOWN.
Concerns about post VTP MRI results being conclusive
Phase II Hypertension, Pulmonary trial by University of Oxford. Stop reason: OPERATIONAL.
Study never started.
Phase I HIV-1 trial by University of Oxford. Stop reason: OPERATIONAL.
Slow recruitment therefore study was stopped after 95% volunteers were enrolled.
Phase II Uncomplicated Falciparum Malaria trial by University of Oxford. Stop reason: OTHER/UNKNOWN.
Change of the study site due to the current political climate in Myanmar.