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University of Nebraska clinical trial failures
Review 56 stopped clinical trials from University of Nebraska, including disease areas, phases, and classified stop reasons.
This page groups real ClinicalTrials.gov-derived stopped trial records. The strongest added signal is the stop-reason classification: 6 of these records are likely biological failure signals, while the rest may reflect operational, strategic, regulatory, funding, enrollment, or unclear stop reasons.
Dominant stop reasons
- OPERATIONAL
- 26
- OTHER/UNKNOWN
- 24
- SAFETY
- 5
- EFFICACY/FUTILITY
- 1
Notable sponsors
- University of Nebraska
- 56
Related phases
- Phase I
- 15
- Phase II
- 15
- Phase IV
- 10
- Unknown
- 9
- Early Phase I
- 5
Crawlable stopped-trial records
Open ExploreShowing up to 56 representative records from this slice. Each link opens the trial detail page with source attribution and stop-reason context.
Phase I Lung Cancer trial by University of Nebraska. Stop reason: OPERATIONAL.
Poor accrual
Phase II Meningioma trial by University of Nebraska. Stop reason: OTHER/UNKNOWN.
Protocol not moving forward.
Phase II Pancreas Cancer trial by University of Nebraska. Stop reason: EFFICACY/FUTILITY.
Due to low accrual and futility
Phase I Recurrent Glioblastoma trial by University of Nebraska. Stop reason: OTHER/UNKNOWN.
PI leaving institution.
Phase I Irritable Mood trial by University of Nebraska. Stop reason: SAFETY.
Per DSMB's recommendation
Phase I Hyposmia trial by University of Nebraska. Stop reason: OTHER/UNKNOWN.
sponsor discontinued site participation
Phase I COVID 19 trial by University of Nebraska. Stop reason: OPERATIONAL.
Unable to recruit sufficient number of subjects.
Unknown Coronary Stenosis trial by University of Nebraska. Stop reason: OTHER/UNKNOWN.
No stop-reason text available in the compact dataset.
Phase IV Diabetes Mellitus trial by University of Nebraska. Stop reason: OPERATIONAL.
No Subjects enrolled
Phase I Leukemia trial by University of Nebraska. Stop reason: OTHER/UNKNOWN.
PI has left institution and is taking the study with him.
Phase IV Peripheral Artery Disease trial by University of Nebraska. Stop reason: OPERATIONAL.
discontinued due to change in operating plans prior to study initiation and enrollment
Phase I Periodontitis, Adult trial by University of Nebraska. Stop reason: OTHER/UNKNOWN.
Study was unable to obtain IRB approval because CBD was not legal in Nebraska at that time.
Early Phase I Atopic Dermatitis trial by University of Nebraska. Stop reason: OPERATIONAL.
Study never started
Phase IV White Spot Lesion trial by University of Nebraska. Stop reason: OPERATIONAL.
Study not initiated
Unknown Postoperative Nausea and Vomiting trial by University of Nebraska. Stop reason: OTHER/UNKNOWN.
It didn't get IRB approval.
Phase III Dysphagia trial by University of Nebraska. Stop reason: OTHER/UNKNOWN.
Poor compliance with data collection - too many intervals.
Phase II Plasma Cell Myeloma trial by University of Nebraska. Stop reason: OPERATIONAL.
Study terminated prematurely due to poor recruitment.
Phase II Glaucoma trial by University of Nebraska. Stop reason: SAFETY.
Study stopped and data not analyzed
Phase I Islets of Langerhans Transplantation trial by University of Nebraska. Stop reason: OTHER/UNKNOWN.
Per Coordinator: study was closed and no cadaveric implants were performed
Phase II HER2-negative Breast Cancer trial by University of Nebraska. Stop reason: SAFETY.
drug toxicity
Early Phase I Graft Pancreatitis trial by University of Nebraska. Stop reason: OTHER/UNKNOWN.
Logistic problems with adequately timely organ collection and transport
Phase IV Renal Insufficiency, Chronic trial by University of Nebraska. Stop reason: OPERATIONAL.
Study was stopped due to the COVID pandemic
Early Phase I Chronic Hepatitis C trial by University of Nebraska. Stop reason: OTHER/UNKNOWN.
new medications with improved response released
Phase I Anaplastic Astrocytoma trial by University of Nebraska. Stop reason: OTHER/UNKNOWN.
No stop-reason text available in the compact dataset.
Phase II Kidney Cancer trial by University of Nebraska. Stop reason: OPERATIONAL.
Low accrual rate
Phase II Adenocarcinoma of the Gastroesophageal Junction trial by University of Nebraska. Stop reason: SAFETY.
Drug manufacturer - Amgen requested study stop, per DSMB observation in POWER trial
Phase I Glioblastoma trial by University of Nebraska. Stop reason: OTHER/UNKNOWN.
No stop-reason text available in the compact dataset.
Early Phase I Contiguous Stage II Adult Diffuse Large Cell Lymphoma trial by University of Nebraska. Stop reason: OTHER/UNKNOWN.
Manufacturer is no longer making the drug.
Unknown Nephropathy trial by University of Nebraska. Stop reason: OTHER/UNKNOWN.
Technical measurement problems led to unreliable or uninterpretable data.
Phase II Lymphoma trial by University of Nebraska. Stop reason: OTHER/UNKNOWN.
Genitope suspend drug development by decision made by the FDA March 6, 2008.
Phase I Myelodysplastic Syndromes trial by University of Nebraska. Stop reason: OPERATIONAL.
Genzyme discontinued Funding
Phase I Adenocarcinoma of the Prostate trial by University of Nebraska. Stop reason: OPERATIONAL.
study sponsors withdrew support for the study drug.
Phase II Prostate Cancer trial by University of Nebraska. Stop reason: OPERATIONAL.
PI left UNMC
Phase IV Type 2 Diabetes trial by University of Nebraska. Stop reason: OPERATIONAL.
lack of funding
Phase II Breast Cancer trial by University of Nebraska. Stop reason: OPERATIONAL.
study drug was removed from the market and low enrollment.
Phase IV Sleep Disorder trial by University of Nebraska. Stop reason: OPERATIONAL.
Unsuccessful in recruiting appropriate subjects.
Phase II Head and Neck Squamous Cell Carcinoma trial by University of Nebraska. Stop reason: OPERATIONAL.
low enrollment
Phase I Multiple Myeloma trial by University of Nebraska. Stop reason: OTHER/UNKNOWN.
Phase I response to treatment was not as expected and the myeloma field in treatment has changed since initiating the study, so investigators felt the study should not be pursued into Phase II.
Phase IV Short Bowel Syndrome trial by University of Nebraska. Stop reason: OPERATIONAL.
Lack of Enrollment
Unknown Smoking Cessation trial by University of Nebraska. Stop reason: OTHER/UNKNOWN.
primary analyses found unfeasible
Unknown Cigarette Smoking trial by University of Nebraska. Stop reason: OTHER/UNKNOWN.
primary analyses found futile
Phase II Accelerated Phase Chronic Myelogenous Leukemia trial by University of Nebraska. Stop reason: OPERATIONAL.
Study was closed to accrual for safety related to the frequency of BK infections.
Early Phase I Nasal Sinus trial by University of Nebraska. Stop reason: OPERATIONAL.
Decrease in accrual during the COVID-19 pandemic and several sites withdrawing
Phase I Cardiac Hypertrophy trial by University of Nebraska. Stop reason: OPERATIONAL.
PI left University and project not continued
Phase III Erectile Dysfunction trial by University of Nebraska. Stop reason: OPERATIONAL.
low enrollment
Phase IV Multiple Sclerosis trial by University of Nebraska. Stop reason: OTHER/UNKNOWN.
Not approved by IRB
Phase II Kidney Cancer trial by University of Nebraska. Stop reason: SAFETY.
safety reasons
Phase IV Local Anesthesia trial by University of Nebraska. Stop reason: OPERATIONAL.
IRB protocol administratively closed, Continuing Review or Study Completion Report not submitted
Phase II Diabetic Macular Edema trial by University of Nebraska. Stop reason: OPERATIONAL.
Funding lost and study never started
Unknown Chronic Hepatitis C trial by University of Nebraska. Stop reason: OPERATIONAL.
lack of enrollment
Unknown Wounds trial by University of Nebraska. Stop reason: OTHER/UNKNOWN.
Study closed with no subjects accrued. PI decided to stop study.
Phase II Cerebral Vasospasm trial by University of Nebraska. Stop reason: OPERATIONAL.
PI decision
Phase I Chronic Myeloproliferative Disorders trial by University of Nebraska. Stop reason: OTHER/UNKNOWN.
Screenings yielded inadequate eligible subjects to enroll.
Unknown Recurrent Prostate Cancer trial by University of Nebraska. Stop reason: OTHER/UNKNOWN.
Other more favorable treatments are now available.
Unknown Short Bowel Syndrome trial by University of Nebraska. Stop reason: OTHER/UNKNOWN.
No stop-reason text available in the compact dataset.
Phase IV Pain, Postoperative trial by University of Nebraska. Stop reason: OPERATIONAL.
low enrollment