Sponsor hub
University of Michigan clinical trial failures
Review 39 stopped clinical trials from University of Michigan, including disease areas, phases, and classified stop reasons.
This page groups real ClinicalTrials.gov-derived stopped trial records. The strongest added signal is the stop-reason classification: 3 of these records are likely biological failure signals, while the rest may reflect operational, strategic, regulatory, funding, enrollment, or unclear stop reasons.
Dominant stop reasons
- OPERATIONAL
- 26
- OTHER/UNKNOWN
- 10
- EFFICACY/FUTILITY
- 3
Notable sponsors
- University of Michigan
- 39
Related phases
- Phase IV
- 12
- Phase II
- 11
- Unknown
- 7
- Phase I
- 5
- Phase III
- 4
Crawlable stopped-trial records
Open ExploreShowing up to 39 representative records from this slice. Each link opens the trial detail page with source attribution and stop-reason context.
Phase III Cavities of Teeth trial by University of Michigan. Stop reason: EFFICACY/FUTILITY.
The trial stopped early due to meeting interim analysis early stopping rules. Active participants at the time of the interim analyses results did complete their remaining study visits. No new participants were enrolled.
Phase I Retinitis Pigmentosa trial by University of Michigan. Stop reason: OPERATIONAL.
Unable to recruit additional participants after multiple extensions to planned enrollment period.
Unknown Pancreas trial by University of Michigan. Stop reason: OPERATIONAL.
Lack of funding and change in research direction.
Phase II Diabetes Mellitus Type 2 trial by University of Michigan. Stop reason: OPERATIONAL.
Due to limited funding, trial was suspended, intending to restart with additional funds; then preliminary results were obtained, and research moved on to placebo controlled trial. Results for both have been published.
Phase I Congenital Heart Disease trial by University of Michigan. Stop reason: OTHER/UNKNOWN.
Investigator Retirement
Phase II Mild Traumatic Brain Injury trial by University of Michigan. Stop reason: OPERATIONAL.
Slow accrual of patients, lack of financial resources
Phase IV Hypertension trial by University of Michigan. Stop reason: OPERATIONAL.
Issues relate to COVID-19 and staffing challenges, as well as very tight finances.
Unknown Colonic Dysplasia trial by University of Michigan. Stop reason: OPERATIONAL.
Study terminated due to equipment breakage and lack of funding.
Phase I Barrett Esophagus trial by University of Michigan. Stop reason: OTHER/UNKNOWN.
Study had to be terminated for lack of dimer and inability to produce more at this time.
Phase II Disorder Related to Lung Transplantation trial by University of Michigan. Stop reason: OPERATIONAL.
Slow and delayed recruitment due in part to COVID, led to a decision to end funding and terminate the trial.
Phase II Single-ventricle trial by University of Michigan. Stop reason: OPERATIONAL.
Staffing changes impacted by COVID-19 pandemic resulting in inadequate personnel to facilitate study.
Phase IV Obstructive Sleep Apnea trial by University of Michigan. Stop reason: OPERATIONAL.
Was on hold due to Covid then we were not able to initiate the funding again after such a long hold and loss of team members.
Phase III Other Abnormal Granulation Tissue Nos trial by University of Michigan. Stop reason: OPERATIONAL.
enrollment difficulties
Phase IV Pruritus trial by University of Michigan. Stop reason: EFFICACY/FUTILITY.
Interim analysis showed no difference between groups
Phase II Bone Pain trial by University of Michigan. Stop reason: OPERATIONAL.
Poor enrollment
Phase IV Femoroacetabular Impingement trial by University of Michigan. Stop reason: OPERATIONAL.
low enrollment
Unknown Idiopathic Gastroparesis trial by University of Michigan. Stop reason: OPERATIONAL.
Inadequate recruitment numbers
Phase III Postoperative Urinary Retention trial by University of Michigan. Stop reason: EFFICACY/FUTILITY.
interim analysis revealed no significant difference between study groups \& increased sample size required to gain significance.
Phase II Knee Osteoarthritis trial by University of Michigan. Stop reason: OPERATIONAL.
Terminated prematurely due to feasibility issues with rate of recruitment
Phase IV Fontan Procedure trial by University of Michigan. Stop reason: OPERATIONAL.
This study was terminated due to inability to recruit sufficient patients.
Phase II Implant trial by University of Michigan. Stop reason: OTHER/UNKNOWN.
Study was terminated due to patient complications unrelated to study drugs
Unknown Chronic Kidney Disease trial by University of Michigan. Stop reason: OPERATIONAL.
Futility: Impossible to recruit enough hypertensive participants to match Chronic Kidney Disease (CKD) participants on needed parameters.
Phase III Croup trial by University of Michigan. Stop reason: OTHER/UNKNOWN.
No stop-reason text available in the compact dataset.
Phase IV Crohn's Disease trial by University of Michigan. Stop reason: OPERATIONAL.
Unable to enroll at rate anticipated, insufft low vitamin D in clin rem @ 5 sites
Phase IV Atrial Fibrillation trial by University of Michigan. Stop reason: OPERATIONAL.
unable to secure funding and long term follow up
Phase II Functional Abdominal Pain trial by University of Michigan. Stop reason: OPERATIONAL.
Due to the wide availability of the drug in clinical practice, it was impossible to recruit adequate numbers for scientific power.
Phase II Urothelial Carcinoma trial by University of Michigan. Stop reason: OPERATIONAL.
Study closed due to poor accrual
Phase IV Acute Kidney Injury trial by University of Michigan. Stop reason: OTHER/UNKNOWN.
Insufficient number of subjects could be enrolled.
Unknown Changes in Brain Network Connectivity trial by University of Michigan. Stop reason: OPERATIONAL.
Funding cessation.
Unknown Bicuspid Aortic Valve trial by University of Michigan. Stop reason: OPERATIONAL.
Due to low enrollment the decision was made to terminate study prior to final data collection for any individual.
Phase II Interstitial Lung Disease trial by University of Michigan. Stop reason: OTHER/UNKNOWN.
Departure of study team
Phase I Heart Transplant trial by University of Michigan. Stop reason: OTHER/UNKNOWN.
Technical difficulty with Endo-PAT machine
Phase IV Scleroderma trial by University of Michigan. Stop reason: OTHER/UNKNOWN.
No stop-reason text available in the compact dataset.
Phase II Depression trial by University of Michigan. Stop reason: OPERATIONAL.
Lack of funding to complete the trial phase of the study.
Phase IV Heart Failure trial by University of Michigan. Stop reason: OPERATIONAL.
Unable to recruit sufficient number of patients.
Phase IV Heart Failure trial by University of Michigan. Stop reason: OTHER/UNKNOWN.
Lack of eligible patients
Phase IV Complications trial by University of Michigan. Stop reason: OPERATIONAL.
Change in standard of care, no possibility of recruitment
Phase I Crohn's Disease trial by University of Michigan. Stop reason: OTHER/UNKNOWN.
PI leaving UM at the end of the month
Unknown Subarachnoid Hemorrhage trial by University of Michigan. Stop reason: OPERATIONAL.
Funding withdrawn. Design not feasible.