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University of Miami clinical trial failures
Review 68 stopped clinical trials from University of Miami, including disease areas, phases, and classified stop reasons.
This page groups real ClinicalTrials.gov-derived stopped trial records. The strongest added signal is the stop-reason classification: 3 of these records are likely biological failure signals, while the rest may reflect operational, strategic, regulatory, funding, enrollment, or unclear stop reasons.
Dominant stop reasons
- OPERATIONAL
- 42
- OTHER/UNKNOWN
- 23
- EFFICACY/FUTILITY
- 2
- SAFETY
- 1
Notable sponsors
- University of Miami
- 68
Related phases
- Phase II
- 24
- Phase IV
- 21
- Phase I
- 12
- Phase III
- 6
- Unknown
- 3
Crawlable stopped-trial records
Open ExploreShowing up to 68 representative records from this slice. Each link opens the trial detail page with source attribution and stop-reason context.
Phase II Unresectable Hepatocellular Carcinoma trial by University of Miami. Stop reason: OPERATIONAL.
Investigator decision
Phase IV Schizophrenia trial by University of Miami. Stop reason: OPERATIONAL.
Recruitment issues
Phase IV Ventilator Associated Pneumonia trial by University of Miami. Stop reason: OPERATIONAL.
The rate of enrollment was slower than expected
Phase II Short Gut Syndrome trial by University of Miami. Stop reason: OPERATIONAL.
Inability to recruit further patients for study
Phase IV Tobacco Smoking trial by University of Miami. Stop reason: OPERATIONAL.
Recruitment for the study proved to be a significant challenge, raising important concerns about its overall feasibility.
Phase III Glaucoma trial by University of Miami. Stop reason: OTHER/UNKNOWN.
No patients had abnormal PERG and could not be included in the first two arms from the baseline timepoint.
Phase IV Eye Infections, Bacterial trial by University of Miami. Stop reason: OTHER/UNKNOWN.
sample microbiologic results where not consistent
Phase III Spinal Disorder trial by University of Miami. Stop reason: OTHER/UNKNOWN.
Study drug was not compliant with research pharmacy
Phase II Diffuse Large B Cell Lymphoma trial by University of Miami. Stop reason: OPERATIONAL.
Investigator Decision
Phase I Erectile Dysfunction With Diabetes Mellitus trial by University of Miami. Stop reason: OPERATIONAL.
Funding ended
Phase IV Tears trial by University of Miami. Stop reason: OPERATIONAL.
Patient recruitment shortage and study coordinator turnover
Phase IV Post-operative Pain trial by University of Miami. Stop reason: OTHER/UNKNOWN.
Study will no longer be conducted
Phase II Cervical Cancer trial by University of Miami. Stop reason: OPERATIONAL.
Investigator left institution
Phase IV Living Donor Kidney Transplants Patients trial by University of Miami. Stop reason: OPERATIONAL.
Lost funding source
Phase II Acne trial by University of Miami. Stop reason: OPERATIONAL.
Enrollment timeline ended
Phase IV Type 2 Diabetes Mellitus trial by University of Miami. Stop reason: OPERATIONAL.
PI left University of Miami
Phase IV Chronic Shoulder Pain trial by University of Miami. Stop reason: OTHER/UNKNOWN.
Unable to feasibly complete study.
Phase II Fallopian Tube Cancer trial by University of Miami. Stop reason: OPERATIONAL.
Investigator left institution
Phase IV Eyelid Diseases trial by University of Miami. Stop reason: OPERATIONAL.
Research team dissembled because of no funding.
Phase IV Covid19 trial by University of Miami. Stop reason: OPERATIONAL.
coronavirus omicron variant infection typically not associated with delirium and agitation severely hampered recruitment.
Phase II Gestational Trophoblastic Neoplasia trial by University of Miami. Stop reason: OTHER/UNKNOWN.
PI is leaving the University.
Phase II Head and Neck Squamous Cell Carcinoma trial by University of Miami. Stop reason: OPERATIONAL.
Investigator Decision
Phase IV Arthroplasty Complications trial by University of Miami. Stop reason: OPERATIONAL.
Did not acquire funding to pursue study
Phase II Cerebrospinal Fluid Leak trial by University of Miami. Stop reason: OTHER/UNKNOWN.
No participants were identified per inclusion/exclusion criteria
Phase II Multiple Sclerosis trial by University of Miami. Stop reason: OTHER/UNKNOWN.
Withdrawn as more data drug analysis is recommended before the study.
Phase IV Coronavirus Infection trial by University of Miami. Stop reason: OPERATIONAL.
Logistical challenges amid COVID-19 pandemic and lack of financial support
Phase III Anosmia trial by University of Miami. Stop reason: OTHER/UNKNOWN.
Poor participant compliance
Phase II Cystic Fibrosis trial by University of Miami. Stop reason: OPERATIONAL.
due to slow enrollment and approval of the Trikafta for CF patients
Phase IV Monoclonal Gammopathies trial by University of Miami. Stop reason: OPERATIONAL.
Lack of funds to cover the costs of the study medications
Phase IV COPD trial by University of Miami. Stop reason: OPERATIONAL.
Difficulty in recruitment
Phase I Infection Due to Resistant Organism trial by University of Miami. Stop reason: OTHER/UNKNOWN.
safety
Phase II Cerebrospinal Fluid Leak trial by University of Miami. Stop reason: OTHER/UNKNOWN.
No participants were identified per inclusion/exclusion criteria
Early Phase I Uveal Melanoma trial by University of Miami. Stop reason: OPERATIONAL.
Investigator Decision
Phase III Ischemic Stroke trial by University of Miami. Stop reason: OPERATIONAL.
Recruitment halted by DSMB following interim analysis.
Phase IV Venous Thromboembolism trial by University of Miami. Stop reason: EFFICACY/FUTILITY.
Terminated due to futility and less subjects meeting entry criteria
Phase II Epstein Barr Virus Associated Non Hodgkin's Lymphoma trial by University of Miami. Stop reason: OPERATIONAL.
Investigator Decision
Phase III Hepatic Encephalopathy trial by University of Miami. Stop reason: OPERATIONAL.
Difficult to recruit participants
Phase II Prostate Cancer trial by University of Miami. Stop reason: OPERATIONAL.
Lack of Accrual and Inadequate Funding
Phase IV AIDS trial by University of Miami. Stop reason: OPERATIONAL.
No Further Funding
Phase II Pneumothorax Iatrogenic Postprocedural trial by University of Miami. Stop reason: OTHER/UNKNOWN.
Will re-open at another time
Phase I Breast Cancer trial by University of Miami. Stop reason: SAFETY.
Terminated due to low accrual and toxicity concerns.
Phase I Leiomyosarcoma trial by University of Miami. Stop reason: OPERATIONAL.
Sponsor Decision
Early Phase I Hemodynamic Instability trial by University of Miami. Stop reason: OTHER/UNKNOWN.
I discontinued this study because I transferred to another institution.
Phase IV Lymphoma trial by University of Miami. Stop reason: OPERATIONAL.
Investigator Decision
Phase I Primary Sclerosing Cholangitis trial by University of Miami. Stop reason: OTHER/UNKNOWN.
No stop-reason text available in the compact dataset.
Phase I Cholangiocarcinoma trial by University of Miami. Stop reason: OPERATIONAL.
Lack of Funding
Unknown Lymphoma trial by University of Miami. Stop reason: OPERATIONAL.
Funding
Phase I Lung Cancer trial by University of Miami. Stop reason: OTHER/UNKNOWN.
Per request of Principal Investigator this study was closed.
Phase IV Pain trial by University of Miami. Stop reason: OTHER/UNKNOWN.
eyes that received gel had slightly thinner than intended flaps
Phase II Lymphoma trial by University of Miami. Stop reason: OPERATIONAL.
Investigator Decision due to insufficient accrual.
Unknown Prematurity trial by University of Miami. Stop reason: OTHER/UNKNOWN.
Safety
Phase II Multiple Myeloma trial by University of Miami. Stop reason: OPERATIONAL.
Lack of adequate accrual.
Phase I Sickle Cell Disease trial by University of Miami. Stop reason: OPERATIONAL.
Inability to recruit patients into the study.
Phase II Colorectal Cancer trial by University of Miami. Stop reason: OTHER/UNKNOWN.
Study terminated by University of Miami Institutional Review Board
Phase II Squamous Cell Carcinoma trial by University of Miami. Stop reason: EFFICACY/FUTILITY.
Early termination due to lack of efficacy (overall response)
Phase II Type 1 Diabetes Mellitus trial by University of Miami. Stop reason: OTHER/UNKNOWN.
We did not achieve a tolerogenic profile. Subjects withdrew from protocol and enrolled in other islet transplant trials.
Phase II Colorectal Cancer trial by University of Miami. Stop reason: OPERATIONAL.
Low Accrual
Phase II Gastric Cancer trial by University of Miami. Stop reason: OTHER/UNKNOWN.
No stop-reason text available in the compact dataset.
Phase II Glioblastoma trial by University of Miami. Stop reason: OPERATIONAL.
Lack of Accrual/Enrollment
Phase IV HIV trial by University of Miami. Stop reason: OPERATIONAL.
Poor enrollment.
Unknown Lymphoma trial by University of Miami. Stop reason: OTHER/UNKNOWN.
No stop-reason text available in the compact dataset.
Phase I Multiple Myeloma and Plasma Cell Neoplasm trial by University of Miami. Stop reason: OPERATIONAL.
Temporarily closed to accrual pending availablity of drug.
Phase I Cervical Cancer trial by University of Miami. Stop reason: OTHER/UNKNOWN.
No stop-reason text available in the compact dataset.
Phase II Lymphoma trial by University of Miami. Stop reason: OTHER/UNKNOWN.
No stop-reason text available in the compact dataset.
Phase IV Unipolar Major Depression trial by University of Miami. Stop reason: OPERATIONAL.
Funding not received
Phase I Ovarian Cancer trial by University of Miami. Stop reason: OPERATIONAL.
Study voluntarily stopped by Principal Investigator due to lack of accrual.
Phase III Diabetes Mellitus, Type 2 trial by University of Miami. Stop reason: OPERATIONAL.
Unable to recruit sufficient study subjects
Phase I Prostate Cancer trial by University of Miami. Stop reason: OPERATIONAL.
Withdrawal of Funding