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University of Maryland, Baltimore clinical trial failures
Review 79 stopped clinical trials from University of Maryland, Baltimore, including disease areas, phases, and classified stop reasons.
This page groups real ClinicalTrials.gov-derived stopped trial records. The strongest added signal is the stop-reason classification: 1 of these records are likely biological failure signals, while the rest may reflect operational, strategic, regulatory, funding, enrollment, or unclear stop reasons.
Dominant stop reasons
- OPERATIONAL
- 51
- OTHER/UNKNOWN
- 26
- REGULATORY
- 1
- SAFETY
- 1
Notable sponsors
- University of Maryland, Baltimore
- 79
Related phases
- Phase II
- 29
- Phase IV
- 17
- Phase I
- 15
- Unknown
- 11
- Early Phase I
- 4
Crawlable stopped-trial records
Open ExploreShowing up to 79 representative records from this slice. Each link opens the trial detail page with source attribution and stop-reason context.
Phase II Intracerebral Haemorrhage, Intraventricular trial by University of Maryland, Baltimore. Stop reason: OPERATIONAL.
Loss of Financial Sponsor
Unknown Breast Cancer trial by University of Maryland, Baltimore. Stop reason: OPERATIONAL.
This study was terminated due to slow accrual, and this due to the changing practice patterns, and difficulties with insurance coverage for some of the study related tests, such as OncotypeDx.
Phase III COVID-19 trial by University of Maryland, Baltimore. Stop reason: OPERATIONAL.
The Principal Investigator left the institution. The study was halted prematurely.
Phase I Acute Myeloid Leukemia trial by University of Maryland, Baltimore. Stop reason: OPERATIONAL.
Pharmaceutical Company withdrew support and investigational product
Phase I Extensive-stage Small-cell Lung Cancer trial by University of Maryland, Baltimore. Stop reason: OTHER/UNKNOWN.
PI changed institution. Not yet approved at current location.
Unknown Periprosthetic Joint Infection trial by University of Maryland, Baltimore. Stop reason: OPERATIONAL.
No participants enrolled.
Phase I Diabetic Neuropathy Peripheral trial by University of Maryland, Baltimore. Stop reason: OPERATIONAL.
Completed the pilot study and grant funding not obtained to continue to the main phase 2 study. The pilot study did not show a statistical significance in the primary or secondary outcome measures.
Early Phase I Type1 Diabetes Mellitus trial by University of Maryland, Baltimore. Stop reason: OTHER/UNKNOWN.
We were unable to obtain GLP-1
Phase I Degenerative Lumbar Spinal Stenosis trial by University of Maryland, Baltimore. Stop reason: OPERATIONAL.
Study was not feasible due to logistical and implementation challenges. No participants were enrolled and the study will not proceed further.
Phase I Type 2 Diabetes trial by University of Maryland, Baltimore. Stop reason: OPERATIONAL.
We concluded that it would not be possible to meet our recruitment targets within the available budget. The study was ended when the funding ended.
Phase II Endometrial Cancer trial by University of Maryland, Baltimore. Stop reason: OPERATIONAL.
SOC changed and low enrollment
Phase IV Substance Use Disorders trial by University of Maryland, Baltimore. Stop reason: OTHER/UNKNOWN.
The study was not able to enroll adequate participants within predetermined timelines
Phase III Heart Disease End Stage trial by University of Maryland, Baltimore. Stop reason: OPERATIONAL.
Standard practice change prohibited enrollment
Phase I Relapsed/Refractory Multiple Myeloma trial by University of Maryland, Baltimore. Stop reason: REGULATORY.
The study was terminated due to FDA withdrawal of the drug and lack of enrollment with available BCMA therapies that were deemed safer.
Phase II Sarcoidosis, Pulmonary trial by University of Maryland, Baltimore. Stop reason: OTHER/UNKNOWN.
Many of sarcoidosis patients in this area already taking metformin
Phase IV Heart Failure NYHA Class IV trial by University of Maryland, Baltimore. Stop reason: OPERATIONAL.
Unable to obtain funding
Phase I Cognitive Change trial by University of Maryland, Baltimore. Stop reason: OTHER/UNKNOWN.
Drug supplier did not come through.
Phase II Temporomandibular Disorders trial by University of Maryland, Baltimore. Stop reason: OPERATIONAL.
Low enrollment rate
Phase II Trigeminal Neuropathy trial by University of Maryland, Baltimore. Stop reason: OPERATIONAL.
Low enrollment rate
Phase III Pulmonary Embolism trial by University of Maryland, Baltimore. Stop reason: OPERATIONAL.
Study was cancelled by funding agency before starting enrollment.
Phase I Opioid Use Disorder trial by University of Maryland, Baltimore. Stop reason: OTHER/UNKNOWN.
Study funds were exhausted
Phase I Schizophrenia trial by University of Maryland, Baltimore. Stop reason: OPERATIONAL.
PI moved to another institution before enrollment could start.
Phase II Diabetes Mellitus, Type 2 trial by University of Maryland, Baltimore. Stop reason: OPERATIONAL.
Lack of enrollment
Phase II Traumatic Brain Injury trial by University of Maryland, Baltimore. Stop reason: OTHER/UNKNOWN.
Study will not be intiated
Phase II Alcohol Abuse trial by University of Maryland, Baltimore. Stop reason: OPERATIONAL.
Difficulty recruiting target sample
Phase II Disorder Related to Lung Transplantation trial by University of Maryland, Baltimore. Stop reason: OTHER/UNKNOWN.
Study did not proceed to IRB approval.
Early Phase I Hepatitis C trial by University of Maryland, Baltimore. Stop reason: OPERATIONAL.
never started
Phase IV Congestive Heart Failure trial by University of Maryland, Baltimore. Stop reason: OTHER/UNKNOWN.
protocol change
Phase I Asthma trial by University of Maryland, Baltimore. Stop reason: OPERATIONAL.
Inadequate recruitment
Phase IV Cholera Vaccination trial by University of Maryland, Baltimore. Stop reason: OPERATIONAL.
lack of funding
Phase II Histologically Proven Diagnosis of Glioblastoma or Gliosarcoma (WHO Grade IV) trial by University of Maryland, Baltimore. Stop reason: OPERATIONAL.
Poor accrual
Phase I Cirrhosis trial by University of Maryland, Baltimore. Stop reason: OPERATIONAL.
The study is closed due to lack of funding to support the study.
Phase IV Transplant Glomerulopathy trial by University of Maryland, Baltimore. Stop reason: OPERATIONAL.
Slow Enrollment
Phase IV Diabetes Mellitus trial by University of Maryland, Baltimore. Stop reason: OPERATIONAL.
Did not meet recruitment targets.
Phase II Metastatic Breast Cancer trial by University of Maryland, Baltimore. Stop reason: OPERATIONAL.
funding withdrawn by sponsor
Phase II Estrogen Receptor-negative Breast Cancer trial by University of Maryland, Baltimore. Stop reason: OPERATIONAL.
low accrual
Unknown Osteoporosis Pseudoglioma Syndrome trial by University of Maryland, Baltimore. Stop reason: OPERATIONAL.
it was never started because it was never funded
Phase IV Kidney Transplant trial by University of Maryland, Baltimore. Stop reason: OPERATIONAL.
The trial was stopped because of slow recruitment.
Early Phase I Ameliorating Oxidative Stress in Type 1 Diabetes trial by University of Maryland, Baltimore. Stop reason: OPERATIONAL.
COVID
Unknown Induction of Labor Affected Fetus / Newborn trial by University of Maryland, Baltimore. Stop reason: OTHER/UNKNOWN.
in error
Unknown Schizophrenia trial by University of Maryland, Baltimore. Stop reason: OTHER/UNKNOWN.
No stop-reason text available in the compact dataset.
Phase IV Cardiovascular Diseases trial by University of Maryland, Baltimore. Stop reason: OTHER/UNKNOWN.
Terminated by study sponsor.
Phase II Hypertension trial by University of Maryland, Baltimore. Stop reason: OPERATIONAL.
Not funded
Phase IV Gastro-enteropancreatic Neuroendocrine Tumor trial by University of Maryland, Baltimore. Stop reason: OPERATIONAL.
Subject passed away prior to enrollment
Phase II Obesity trial by University of Maryland, Baltimore. Stop reason: OPERATIONAL.
Not funded
Unknown Alcohol Dependence trial by University of Maryland, Baltimore. Stop reason: OTHER/UNKNOWN.
Principal Investigator was deployed overseas
Phase IV Cardiomyopathy trial by University of Maryland, Baltimore. Stop reason: OPERATIONAL.
Poor enrollment
Phase II Breast Neoplasms trial by University of Maryland, Baltimore. Stop reason: OPERATIONAL.
low accrual
Unknown HIV trial by University of Maryland, Baltimore. Stop reason: OTHER/UNKNOWN.
Inability to enroll subjects.
Phase II Rectal Adenocarcinoma trial by University of Maryland, Baltimore. Stop reason: OPERATIONAL.
Slow accrual, PI left instituion
Phase IV Fluid Overload trial by University of Maryland, Baltimore. Stop reason: OPERATIONAL.
Insufficient rate of patient enrollment/accrual.
Unknown Type 2 Diabetes trial by University of Maryland, Baltimore. Stop reason: OTHER/UNKNOWN.
Sponsor could not fund.
Phase IV HCV Infection trial by University of Maryland, Baltimore. Stop reason: OTHER/UNKNOWN.
Department of Corrections unable to support study at this time and find agreement on publication issue.
Phase II Respiratory Distress Syndrome, Adult trial by University of Maryland, Baltimore. Stop reason: OTHER/UNKNOWN.
Competition from other studies and initiation of a larger multi center trial
Phase I Squamous Cell Carcinoma of Head and Neck trial by University of Maryland, Baltimore. Stop reason: OTHER/UNKNOWN.
major amendments in progress
Phase II Shigella trial by University of Maryland, Baltimore. Stop reason: OTHER/UNKNOWN.
Reactogenicity met study halting criteria
Phase II Shigella trial by University of Maryland, Baltimore. Stop reason: OTHER/UNKNOWN.
Reactogenicity met study halting criteria
Phase II Trauma trial by University of Maryland, Baltimore. Stop reason: OPERATIONAL.
The focus of the project has shifted to publishing a protocol for future trials because we were unable to recruit. Three participants signed the consent forms but withdrew before the randomization.
Phase II Schizophrenia Spectrum Disorders trial by University of Maryland, Baltimore. Stop reason: OPERATIONAL.
not funded
Phase II Opioid-use Disorder trial by University of Maryland, Baltimore. Stop reason: OPERATIONAL.
The FDA determined that there is not adequate safety information to continue clinical investigations using ANS-6637 and Amygdala Neurosciences, the product company of ANS-6637, is no longer pursuing research with this compound.
Phase IV Hepatitis C Virus Infection, Response to Therapy of trial by University of Maryland, Baltimore. Stop reason: OTHER/UNKNOWN.
HCV treatment expansion occurred in Egypt
Phase I Non-Small Cell Lung Cancer, Small Cell Lung Cancer trial by University of Maryland, Baltimore. Stop reason: SAFETY.
Toxicity was not felt to be acceptable for further development.
Unknown Bipolar Disorder trial by University of Maryland, Baltimore. Stop reason: OPERATIONAL.
Due low rate of participation and lack of funding
Phase IV Heart Failure, Congestive trial by University of Maryland, Baltimore. Stop reason: OPERATIONAL.
Funding not available
Phase IV Hiv trial by University of Maryland, Baltimore. Stop reason: OPERATIONAL.
Lack of enrollment
Phase II Bone Marrow Transplantation trial by University of Maryland, Baltimore. Stop reason: OPERATIONAL.
subject recruitment not feasible due to standard care changes
Phase II Inflammatory Bowel Disease trial by University of Maryland, Baltimore. Stop reason: OPERATIONAL.
Study terminated due to insufficient enrollment
Phase I Breast Cancer trial by University of Maryland, Baltimore. Stop reason: OTHER/UNKNOWN.
Lost sponsorship for study drug
Phase II Cocaine Use trial by University of Maryland, Baltimore. Stop reason: OPERATIONAL.
Study funding has not been established
Phase II Schizophrenia trial by University of Maryland, Baltimore. Stop reason: OTHER/UNKNOWN.
Withdrawn due to medication withdrawal from the EMEA
Phase II Prostate Cancer trial by University of Maryland, Baltimore. Stop reason: OTHER/UNKNOWN.
PI No Longer at University of Maryland. Now at Fox Chase
Phase I Small Cell Lung Cancer (SCLC) trial by University of Maryland, Baltimore. Stop reason: OTHER/UNKNOWN.
PI has left the study institution.
Phase IV Diabetes Mellitus, Type 2 trial by University of Maryland, Baltimore. Stop reason: OTHER/UNKNOWN.
No stop-reason text available in the compact dataset.
Phase IV Pelvis Pain Chronic trial by University of Maryland, Baltimore. Stop reason: OPERATIONAL.
Adequate recruitment was not achieved in the time frame allowed.
Early Phase I Metabolic Syndrome trial by University of Maryland, Baltimore. Stop reason: OPERATIONAL.
Lack of funding
Phase II Metastatic Pancreas Cancer trial by University of Maryland, Baltimore. Stop reason: OPERATIONAL.
Funding issues caused the study to not be opened the at local IRB
Unknown Schizophrenia trial by University of Maryland, Baltimore. Stop reason: OPERATIONAL.
Never started
Unknown no Condition, Basic Science trial by University of Maryland, Baltimore. Stop reason: OPERATIONAL.
Unanticipated staff changes are preventing completion within funding period.
Phase II Melanoma (Skin) trial by University of Maryland, Baltimore. Stop reason: OPERATIONAL.
Study was closed at the suggestion of DSMB prior to obtaining target enrollment