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University of Chicago clinical trial failures
Review 89 stopped clinical trials from University of Chicago, including disease areas, phases, and classified stop reasons.
This page groups real ClinicalTrials.gov-derived stopped trial records. The strongest added signal is the stop-reason classification: 3 of these records are likely biological failure signals, while the rest may reflect operational, strategic, regulatory, funding, enrollment, or unclear stop reasons.
Dominant stop reasons
- OPERATIONAL
- 53
- OTHER/UNKNOWN
- 33
- EFFICACY/FUTILITY
- 2
- SAFETY
- 1
Notable sponsors
- University of Chicago
- 89
Related phases
- Phase II
- 41
- Phase I
- 21
- Phase IV
- 17
- Unknown
- 9
- Early Phase I
- 1
Crawlable stopped-trial records
Open ExploreShowing up to 89 representative records from this slice. Each link opens the trial detail page with source attribution and stop-reason context.
Phase II COVID-19 trial by University of Chicago. Stop reason: OPERATIONAL.
Lack of recruitment of patients into the trial
Phase IV Metrorrhagia trial by University of Chicago. Stop reason: OTHER/UNKNOWN.
Data not collected and analyzed; withdrawn due to lack of bandwidth.
Phase II Fibromyalgia trial by University of Chicago. Stop reason: OTHER/UNKNOWN.
PI has left university
Phase II Major Depressive Disorder trial by University of Chicago. Stop reason: OTHER/UNKNOWN.
PI has left the university
Phase I Colorectal Cancer trial by University of Chicago. Stop reason: OPERATIONAL.
enrollment goal met pending determination of evaluable subjects
Phase I Head and Neck Cancer trial by University of Chicago. Stop reason: OTHER/UNKNOWN.
Drug no longer being developed by manufacturer
Phase I Previously Treated Myelodysplastic Syndrome trial by University of Chicago. Stop reason: OPERATIONAL.
Enrollment on hold pending amendment
Early Phase I Multiple Sclerosis trial by University of Chicago. Stop reason: OTHER/UNKNOWN.
Study pending amendment
Phase IV Esophageal Adenocarcinoma trial by University of Chicago. Stop reason: OTHER/UNKNOWN.
Pending data analysis
Phase II Suicidal Ideation trial by University of Chicago. Stop reason: OTHER/UNKNOWN.
PI has left the university
Phase II Diffuse Large B Cell Lymphoma trial by University of Chicago. Stop reason: OPERATIONAL.
Study was closed early due to slow enrollment.
Phase II Triple Negative Breast Neoplasms trial by University of Chicago. Stop reason: OTHER/UNKNOWN.
side effects (rash)
Phase II Melanoma (Skin) trial by University of Chicago. Stop reason: OPERATIONAL.
Drug supply no longer available.
Phase I Prostate Cancer trial by University of Chicago. Stop reason: OTHER/UNKNOWN.
Closed by PI due to not meeting primary endpoint
Phase IV Autism Spectrum Disorder trial by University of Chicago. Stop reason: OPERATIONAL.
lack of funding and difficulty with phlebotomy in children with Autism
Phase II Distal Urethral Cancer trial by University of Chicago. Stop reason: OPERATIONAL.
Unable to meet accrual goal after several years
Phase II Postpartum Hemorrhage trial by University of Chicago. Stop reason: OTHER/UNKNOWN.
Study will be restarted at a later date
Phase I Pancreatic Neuroendocrine Tumor trial by University of Chicago. Stop reason: OPERATIONAL.
0 enrollment
Phase II Prematurity trial by University of Chicago. Stop reason: OPERATIONAL.
The pace of patient enrolledment forced recruitment to stop after 273 patients.
Phase I Prostate Cancer trial by University of Chicago. Stop reason: OTHER/UNKNOWN.
Terminated by the PI
Phase IV Acute Decompensated Heart Failure trial by University of Chicago. Stop reason: OPERATIONAL.
Enrollment goals were not met.
Phase I IDH Mutation trial by University of Chicago. Stop reason: OTHER/UNKNOWN.
unable to accrue
Phase II Colon Cancer trial by University of Chicago. Stop reason: OTHER/UNKNOWN.
unable to accrue
Phase II Metastatic Cancer trial by University of Chicago. Stop reason: OPERATIONAL.
PI left site
Phase I Pleural Mesothelioma trial by University of Chicago. Stop reason: OPERATIONAL.
unable to complete enrollment
Phase II Oropharyngeal Cancer trial by University of Chicago. Stop reason: OTHER/UNKNOWN.
unable to accrue
Phase II Gastroesophageal Junction Adenocarcinoma trial by University of Chicago. Stop reason: OPERATIONAL.
Low accrual.
Phase II Perceived Social Isolation trial by University of Chicago. Stop reason: OPERATIONAL.
Principal Investigator left institution.
Phase I Follicular Lymphoma trial by University of Chicago. Stop reason: OPERATIONAL.
funding
Phase IV Multiple Sclerosis trial by University of Chicago. Stop reason: OPERATIONAL.
Terminated early due to lack of resources.
Unknown Hypoactive Sexual Desire Disorder trial by University of Chicago. Stop reason: OPERATIONAL.
PI left institution cannot be contacted.
Phase IV Nicotine Addiction trial by University of Chicago. Stop reason: OTHER/UNKNOWN.
Investigators no longer wanted to pursue this research topic
Phase I COVID-19 trial by University of Chicago. Stop reason: OTHER/UNKNOWN.
Terminated by PI
Phase II Asthma Chronic trial by University of Chicago. Stop reason: OPERATIONAL.
Inability to accrue patients, particularly after COVID pandemic.
Phase I Emergence From Anesthesia trial by University of Chicago. Stop reason: OTHER/UNKNOWN.
Withdrawn secondary to a change in protocol design forthcoming.
Phase II Anastomotic Leak trial by University of Chicago. Stop reason: OPERATIONAL.
Lack of funding
Phase IV Polycystic Ovary Syndrome trial by University of Chicago. Stop reason: OPERATIONAL.
Did not meet target patient accrual goals
Phase IV Sleep trial by University of Chicago. Stop reason: OPERATIONAL.
Lack of participant recruitment
Phase IV Rotator Cuff Tear trial by University of Chicago. Stop reason: OTHER/UNKNOWN.
The study was withdrawn prior to any participants being enrolled.
Phase II Body Dysmorphic Disorder trial by University of Chicago. Stop reason: OTHER/UNKNOWN.
Focus on other studies
Unknown HIV/AIDS trial by University of Chicago. Stop reason: OPERATIONAL.
COVID-19 caused substantial barriers to recruitment.
Phase II Neuroendocrine Tumors trial by University of Chicago. Stop reason: OPERATIONAL.
Trial funding no longer available.
Phase I Heart Failure trial by University of Chicago. Stop reason: OPERATIONAL.
Low enrollment
Phase I Hepatocellular Carcinoma trial by University of Chicago. Stop reason: OPERATIONAL.
Study stopped due to poor accrual.
Phase II Acute Myeloid Leukemia (AML) trial by University of Chicago. Stop reason: OPERATIONAL.
Poor accrual
Phase I Prostate Cancer trial by University of Chicago. Stop reason: EFFICACY/FUTILITY.
The study was terminated due to lack of efficacy.
Phase II Melanoma trial by University of Chicago. Stop reason: OTHER/UNKNOWN.
The immune monitoring data failed to demonstrate an improvement in any biologic endpoint with denileukin diftitox.
Phase IV Arthritis trial by University of Chicago. Stop reason: OPERATIONAL.
recruitment problems
Phase II Sarcoidosis trial by University of Chicago. Stop reason: OPERATIONAL.
Difficulty in recruiting subjects
Phase II Extensive Stage Small Cell Lung Cancer trial by University of Chicago. Stop reason: OPERATIONAL.
Due to lack of activity and slow accrual
Phase I Hematologic Malignancies trial by University of Chicago. Stop reason: SAFETY.
Study stopped early due to slow accrual and safety concerns.
Phase II Head and Neck Cancer trial by University of Chicago. Stop reason: EFFICACY/FUTILITY.
Primary endpoint reached futility boundary
Phase II Ductal Carcinoma in Situ trial by University of Chicago. Stop reason: OTHER/UNKNOWN.
Drug no longer available
Phase II Head and Neck Cancer trial by University of Chicago. Stop reason: OPERATIONAL.
Slow accrual
Phase II Sarcoidosis trial by University of Chicago. Stop reason: OPERATIONAL.
Funding has been pulled
Phase II Head and Neck Squamous Cell Carcinoma trial by University of Chicago. Stop reason: OTHER/UNKNOWN.
Study stopped early due to investigator conflict of interest.
Unknown Skin Diseases, Bacterial trial by University of Chicago. Stop reason: OPERATIONAL.
slow accrual
Phase II Borderline Personality Disorder trial by University of Chicago. Stop reason: OPERATIONAL.
Funding withdrawn due to inability to accrue
Phase IV Duration of Pain Relief trial by University of Chicago. Stop reason: OTHER/UNKNOWN.
Unable to continue research due to time constraints
Unknown Duration of Pain Relief trial by University of Chicago. Stop reason: OTHER/UNKNOWN.
Unable to continue study due to time constraints
Phase IV Obstructive Sleep Apnea trial by University of Chicago. Stop reason: OPERATIONAL.
Poor accrual
Phase II Breast Cancer trial by University of Chicago. Stop reason: OPERATIONAL.
Study never activated to enrollment.
Phase II Squamous Cell Carcinoma of the Head and Neck trial by University of Chicago. Stop reason: OPERATIONAL.
Site decided not to move forward with trial. Study never opened to enrollment.
Phase II FGFR Gene Amplification trial by University of Chicago. Stop reason: OPERATIONAL.
Study stopped due to poor enrollment.
Phase I Pancreatic Ductal Adenocarcinoma (PDAC) trial by University of Chicago. Stop reason: OPERATIONAL.
Closed early due to poor accrual.
Phase II Hypercalciuria trial by University of Chicago. Stop reason: OPERATIONAL.
The fellow conducting the recruitment and screening left the institution
Phase IV Blood Coagulation Disorders trial by University of Chicago. Stop reason: OPERATIONAL.
The clinical team couldn't recruit patients who met the criteria for enrollment
Unknown Actinic Keratosis trial by University of Chicago. Stop reason: OPERATIONAL.
The study never started due to the Principal Investigator leaving the institution
Phase II Sepsis trial by University of Chicago. Stop reason: OPERATIONAL.
Inadequate recruitment
Phase IV Mechanical Ventilation trial by University of Chicago. Stop reason: OTHER/UNKNOWN.
drug and placebo unavailable
Phase II Diffuse Large B-Cell Lymphoma trial by University of Chicago. Stop reason: OPERATIONAL.
Trials was stopped early due to lack of funding.
Phase I Unspecified Adult Solid Tumor, Protocol Specific trial by University of Chicago. Stop reason: OPERATIONAL.
The study was terminated early due to slow accrual.
Phase I Malignant Pleural Mesothelioma (MPM) trial by University of Chicago. Stop reason: OTHER/UNKNOWN.
PI stopped study due to inability to accrue.
Phase II Asthma trial by University of Chicago. Stop reason: OTHER/UNKNOWN.
Study was not able to be completed, no results analyzed.
Phase II Head and Neck Cancer trial by University of Chicago. Stop reason: OTHER/UNKNOWN.
PI did not attempt to open the study.
Phase II Parkinson's Disease trial by University of Chicago. Stop reason: OTHER/UNKNOWN.
Site did not obtain LIRB approval due to medication usage.
Phase IV Analgesia Duration trial by University of Chicago. Stop reason: OPERATIONAL.
no logistical support to carry out the study fairly
Unknown Clear Cell Renal Cell Carcinoma trial by University of Chicago. Stop reason: OPERATIONAL.
Poor accrual
Unknown Allergic Rhinitis trial by University of Chicago. Stop reason: OPERATIONAL.
Poor recruitment
Phase I Stage IVA Colorectal Cancer trial by University of Chicago. Stop reason: OTHER/UNKNOWN.
Study terminated by PI due to inability to accrue.
Phase I Ulcerative Colitis trial by University of Chicago. Stop reason: OPERATIONAL.
Unable to recruit and enroll eligible subjects.
Phase IV Hepatitis C trial by University of Chicago. Stop reason: OPERATIONAL.
Low accrual
Unknown Breast Cancer trial by University of Chicago. Stop reason: OTHER/UNKNOWN.
Study never opened (terminated as study drug no longer available)
Unknown MRSA Infection trial by University of Chicago. Stop reason: OTHER/UNKNOWN.
Company went out of business.
Phase IV Lower Limb Ischemia trial by University of Chicago. Stop reason: OPERATIONAL.
PI left University
Phase II High Blood Pressure trial by University of Chicago. Stop reason: OPERATIONAL.
Funding was discontinued.
Phase I Osteopetrosis trial by University of Chicago. Stop reason: OPERATIONAL.
Slow enrollment
Phase II Breast Cancer trial by University of Chicago. Stop reason: OPERATIONAL.
a result of slow accrual
Phase II Hematological Disease trial by University of Chicago. Stop reason: OTHER/UNKNOWN.
did not accrue enough patients.