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University Health Network, Toronto clinical trial failures
Review 47 stopped clinical trials from University Health Network, Toronto, including disease areas, phases, and classified stop reasons.
This page groups real ClinicalTrials.gov-derived stopped trial records. The strongest added signal is the stop-reason classification: 0 of these records are likely biological failure signals, while the rest may reflect operational, strategic, regulatory, funding, enrollment, or unclear stop reasons.
Dominant stop reasons
- OPERATIONAL
- 33
- OTHER/UNKNOWN
- 14
Notable sponsors
- University Health Network, Toronto
- 47
Related phases
- Phase II
- 24
- Phase I
- 11
- Unknown
- 5
- Phase III
- 3
- Phase IV
- 3
Crawlable stopped-trial records
Open ExploreShowing up to 47 representative records from this slice. Each link opens the trial detail page with source attribution and stop-reason context.
Phase II Non-Small Cell Lung Cancer (NSCLC) trial by University Health Network, Toronto. Stop reason: OTHER/UNKNOWN.
Study Terminated Prior to trial activation, due to changes in SOC of the treatment
Phase II Arteriovenous Malformations trial by University Health Network, Toronto. Stop reason: OPERATIONAL.
No patients enrolled
Phase III Dravet Syndrome trial by University Health Network, Toronto. Stop reason: OPERATIONAL.
Study recruitment was too slow, not enough funds to sustain it.
Phase II Gram-negative Bacteremia trial by University Health Network, Toronto. Stop reason: OTHER/UNKNOWN.
Study intervention not available. Manufacturer no longer producing MET-2.
Phase II Early Stage Triple Negative ER Low Breast Cancer trial by University Health Network, Toronto. Stop reason: OPERATIONAL.
Terminated with sponsor-investigator agreement due to extended period without enrollment and the absence of foreseeable participant accrual. No participants were enrolled.
Phase II Non Small Cell Lung Cancer trial by University Health Network, Toronto. Stop reason: OPERATIONAL.
Low accrual
Phase II Endometrial Carcinoma trial by University Health Network, Toronto. Stop reason: OPERATIONAL.
Low accrual
Phase II Hepatocellular Carcinoma trial by University Health Network, Toronto. Stop reason: OPERATIONAL.
The study was stopped due to the shift in systemic treatment paradigm for HCC precluding further enrolment.
Phase IV Hiv trial by University Health Network, Toronto. Stop reason: OPERATIONAL.
enrollment futility
Phase III Sickle Cell Disease trial by University Health Network, Toronto. Stop reason: OPERATIONAL.
Study terminated due to slow recruitment.
Phase I Lymphoma, Large B-Cell, Diffuse trial by University Health Network, Toronto. Stop reason: OPERATIONAL.
recruitment challenges and sites who initially expressed interest declined.
Phase I Epithelial Ovarian Cancer trial by University Health Network, Toronto. Stop reason: OPERATIONAL.
Poor recruitment
Phase I Acute Myeloid Leukemia trial by University Health Network, Toronto. Stop reason: OPERATIONAL.
Insufficient Funding
Phase II Ovarian Endometrioid Tumor trial by University Health Network, Toronto. Stop reason: OPERATIONAL.
19 patients screenfailed, stopping recruitment before first patient enrollment to analyze pilot results from screening samples.
Phase II Coronary Artery Disease trial by University Health Network, Toronto. Stop reason: OPERATIONAL.
Lack of Funding
Early Phase I Bladder Cancer trial by University Health Network, Toronto. Stop reason: OPERATIONAL.
Difficulties with accrual
Unknown COVID-19 trial by University Health Network, Toronto. Stop reason: OPERATIONAL.
A Phase III RUXCOVID study evaluating ruxolitinib on top of standard of care (SoC) therapy compared to SoC treatment alone in patients with COVID-19 did not meet its primary endpoint. With this news, recruitment was stopped for this study.
Phase II Prostate Cancer trial by University Health Network, Toronto. Stop reason: OTHER/UNKNOWN.
Drug intervention no longer relevant for the proposed population
Phase II Tourette Syndrome trial by University Health Network, Toronto. Stop reason: OPERATIONAL.
Recruitment/enrollment took too long
Phase II Pancreatic Ductal Adenocarcinoma trial by University Health Network, Toronto. Stop reason: OTHER/UNKNOWN.
Overall clinical activity (ORR) for oleclumab + durvalumab is minimal across tumor types and does not support further evaluation of this doublet.
Phase II Non Small Cell Lung Cancer trial by University Health Network, Toronto. Stop reason: OTHER/UNKNOWN.
Overall clinical activity (ORR) for oleclumab + durvalumab is minimal across tumor types and does not support further evaluation of this doublet.
Phase II Multiple Myeloma trial by University Health Network, Toronto. Stop reason: OPERATIONAL.
Low patient accrual
Phase II Cancer trial by University Health Network, Toronto. Stop reason: OTHER/UNKNOWN.
No participants were enrolled
Phase IV Chronic Pain trial by University Health Network, Toronto. Stop reason: OPERATIONAL.
No recruitment (Feasibility study).
Phase II Portopulmonary Hypertension trial by University Health Network, Toronto. Stop reason: OPERATIONAL.
Poor recruitment.
Unknown Tachyarrhythmia trial by University Health Network, Toronto. Stop reason: OPERATIONAL.
Unable to recruit eligible participants
Unknown Obstructive Sleep Apnea trial by University Health Network, Toronto. Stop reason: OTHER/UNKNOWN.
competing studies
Unknown Anesthesia trial by University Health Network, Toronto. Stop reason: OPERATIONAL.
Recruitment was very low
Phase I Ovarian Cancer trial by University Health Network, Toronto. Stop reason: OPERATIONAL.
Slow accrual
Phase II Adenocarcinoma of the Pancreas trial by University Health Network, Toronto. Stop reason: OTHER/UNKNOWN.
No stop-reason text available in the compact dataset.
Phase II End Stage Renal Disease trial by University Health Network, Toronto. Stop reason: OPERATIONAL.
Poor enrolment
Phase I Multiple Myeloma trial by University Health Network, Toronto. Stop reason: OTHER/UNKNOWN.
The Sponsor decided to stop further manufacture the study drug 'Linsitinib' in Nov 2015.
Phase II HIV-1 Infection trial by University Health Network, Toronto. Stop reason: OPERATIONAL.
Recruitment potential impaired by shift in clinical care whereby practically all HIV patients receive standard treatment as soon as possible after HIV diagnosis
Phase I Breast Cancer trial by University Health Network, Toronto. Stop reason: OPERATIONAL.
Lack of patient accrual
Unknown Pancreatic Adenocarcinoma trial by University Health Network, Toronto. Stop reason: OPERATIONAL.
Study was never initiated
Phase I Biliary Tract Carcinoma trial by University Health Network, Toronto. Stop reason: OPERATIONAL.
Study was never initiated
Phase I Squamous Cell Carcinoma, Head And Neck trial by University Health Network, Toronto. Stop reason: OPERATIONAL.
The study has been terminated due to a change in internal prioritization and not due to any safety concerns.
Phase II Psoriatic Arthritis trial by University Health Network, Toronto. Stop reason: OTHER/UNKNOWN.
No stop-reason text available in the compact dataset.
Phase II Mesothelioma trial by University Health Network, Toronto. Stop reason: OPERATIONAL.
low accrual due to competing study for same group of patients
Phase II Growing Vestibular Schwannomas trial by University Health Network, Toronto. Stop reason: OPERATIONAL.
Study PI passed away We had trouble recruiting for the drug arm
Phase III Hepatitis C Viral Infection trial by University Health Network, Toronto. Stop reason: OPERATIONAL.
difficulty recruiting patients
Phase II Chronic Lymphocytic Leukaemia trial by University Health Network, Toronto. Stop reason: OTHER/UNKNOWN.
Seven years of follow-up \& final analysis done in Dec 2012.
Phase II Renal Cell Carcinoma trial by University Health Network, Toronto. Stop reason: OPERATIONAL.
poor recruitment
Phase I Acute Myeloid Leukemia trial by University Health Network, Toronto. Stop reason: OTHER/UNKNOWN.
No stop-reason text available in the compact dataset.
Phase I Acute Myeloid Leukemia trial by University Health Network, Toronto. Stop reason: OTHER/UNKNOWN.
No stop-reason text available in the compact dataset.
Phase I Metastatic Breast Cancer trial by University Health Network, Toronto. Stop reason: OTHER/UNKNOWN.
Contract with drug supplier expired and was not renewed.
Phase IV Vascular Disease trial by University Health Network, Toronto. Stop reason: OPERATIONAL.
Enrollment slow over 2 years a change in the population less on metoprolol than initially anticipated