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Roswell Park Cancer Institute clinical trial failures
Review 78 stopped clinical trials from Roswell Park Cancer Institute, including disease areas, phases, and classified stop reasons.
This page groups real ClinicalTrials.gov-derived stopped trial records. The strongest added signal is the stop-reason classification: 6 of these records are likely biological failure signals, while the rest may reflect operational, strategic, regulatory, funding, enrollment, or unclear stop reasons.
Dominant stop reasons
- OPERATIONAL
- 44
- OTHER/UNKNOWN
- 28
- EFFICACY/FUTILITY
- 5
- SAFETY
- 1
Notable sponsors
- Roswell Park Cancer Institute
- 78
Related phases
- Phase I
- 38
- Phase II
- 29
- Unknown
- 9
- Early Phase I
- 2
Crawlable stopped-trial records
Open ExploreShowing up to 78 representative records from this slice. Each link opens the trial detail page with source attribution and stop-reason context.
Phase I Advanced Hepatocellular Carcinoma trial by Roswell Park Cancer Institute. Stop reason: OTHER/UNKNOWN.
awaiting agreement with Sponsor
Phase I Recurrent Multiple Myeloma trial by Roswell Park Cancer Institute. Stop reason: OTHER/UNKNOWN.
Sponsor withdrawal of supplying investigational drug
Early Phase I Stage I Non-Small Cell Lung Cancer AJCC v7 trial by Roswell Park Cancer Institute. Stop reason: OPERATIONAL.
low accrual
Phase II HLA-A2 Positive Cells Present trial by Roswell Park Cancer Institute. Stop reason: OPERATIONAL.
Funding completed
Phase I Lung Non-Small Cell Carcinoma trial by Roswell Park Cancer Institute. Stop reason: OPERATIONAL.
low accrual
Phase I Hematopoietic and Lymphoid Cell Neoplasm trial by Roswell Park Cancer Institute. Stop reason: OPERATIONAL.
Low accrual
Phase I Castration-Resistant Prostate Carcinoma trial by Roswell Park Cancer Institute. Stop reason: OTHER/UNKNOWN.
PI closed study
Phase I Soft Tissue Sarcoma trial by Roswell Park Cancer Institute. Stop reason: OTHER/UNKNOWN.
to be submitted at a later date
Phase I Recurrent Chronic Lymphocytic Leukemia trial by Roswell Park Cancer Institute. Stop reason: OPERATIONAL.
Manufacturing issues
Phase II Accelerated Phase Chronic Myelogenous Leukemia, BCR-ABL1 Positive trial by Roswell Park Cancer Institute. Stop reason: EFFICACY/FUTILITY.
Futility analysis determined closure
Phase I Stage IIIC Cutaneous Melanoma AJCC v7 trial by Roswell Park Cancer Institute. Stop reason: EFFICACY/FUTILITY.
interim Analysis
Phase I Anatomic Stage IV Breast Cancer AJCC v8 trial by Roswell Park Cancer Institute. Stop reason: OPERATIONAL.
Funding ended
Phase I Cancer of Ovary trial by Roswell Park Cancer Institute. Stop reason: OPERATIONAL.
lack of funding
Phase I Recurrent Head and Neck Carcinoma trial by Roswell Park Cancer Institute. Stop reason: OPERATIONAL.
Low accrual
Phase II Recurrent Plasma Cell Myeloma trial by Roswell Park Cancer Institute. Stop reason: OPERATIONAL.
funding ended
Phase II Locally Advanced Digestive System Neuroendocrine Carcinoma trial by Roswell Park Cancer Institute. Stop reason: OPERATIONAL.
low accrual
Phase II Anatomic Stage III Breast Cancer AJCC v8 trial by Roswell Park Cancer Institute. Stop reason: OTHER/UNKNOWN.
Study never activated.
Phase I Advanced Pancreatic Ductal Adenocarcinoma trial by Roswell Park Cancer Institute. Stop reason: OTHER/UNKNOWN.
never opened
Phase II Metastatic Microsatellite Stable Colorectal Carcinoma trial by Roswell Park Cancer Institute. Stop reason: OPERATIONAL.
prioritization of studies
Phase I Platinum-Resistant Fallopian Tube Carcinoma trial by Roswell Park Cancer Institute. Stop reason: OPERATIONAL.
Lack of funding
Phase I Advanced Cutaneous Melanoma of the Extremity trial by Roswell Park Cancer Institute. Stop reason: OPERATIONAL.
low accrual
Unknown Tobacco-Related Carcinoma trial by Roswell Park Cancer Institute. Stop reason: OPERATIONAL.
low accrual
Early Phase I Colorectal Carcinoma trial by Roswell Park Cancer Institute. Stop reason: OPERATIONAL.
Issues recruiting
Phase I Stage II Fallopian Tube Cancer AJCC v8 trial by Roswell Park Cancer Institute. Stop reason: OTHER/UNKNOWN.
new study to be created
Phase I Colorectal Cancer trial by Roswell Park Cancer Institute. Stop reason: OTHER/UNKNOWN.
No stop-reason text available in the compact dataset.
Phase I Adult Solid Neoplasm trial by Roswell Park Cancer Institute. Stop reason: OTHER/UNKNOWN.
No stop-reason text available in the compact dataset.
Phase I Cytomegaloviral Infection trial by Roswell Park Cancer Institute. Stop reason: OTHER/UNKNOWN.
Study never approved
Phase II Malignant Bowel Obstruction trial by Roswell Park Cancer Institute. Stop reason: OPERATIONAL.
low accrual
Phase I Castration Levels of Testosterone trial by Roswell Park Cancer Institute. Stop reason: OPERATIONAL.
lack of funding
Phase I Prostate Cancer trial by Roswell Park Cancer Institute. Stop reason: OTHER/UNKNOWN.
no value in finding efficacy
Phase I Lung Cancer trial by Roswell Park Cancer Institute. Stop reason: OTHER/UNKNOWN.
No stop-reason text available in the compact dataset.
Unknown Healthy, no Evidence of Disease trial by Roswell Park Cancer Institute. Stop reason: OTHER/UNKNOWN.
No stop-reason text available in the compact dataset.
Phase I Unspecified Adult Solid Tumor, Protocol Specific trial by Roswell Park Cancer Institute. Stop reason: OTHER/UNKNOWN.
Sponsor did not have funds to continue study
Unknown Stage II Renal Cell Cancer trial by Roswell Park Cancer Institute. Stop reason: OTHER/UNKNOWN.
No stop-reason text available in the compact dataset.
Phase I Clear Cell Renal Cell Carcinoma trial by Roswell Park Cancer Institute. Stop reason: OPERATIONAL.
pts off study, PI left institute
Phase I Lymphoma trial by Roswell Park Cancer Institute. Stop reason: OPERATIONAL.
PI left institute
Phase I Essential Thrombocythemia trial by Roswell Park Cancer Institute. Stop reason: OPERATIONAL.
low accrual
Phase I Adult Acute Basophilic Leukemia trial by Roswell Park Cancer Institute. Stop reason: OTHER/UNKNOWN.
Sponsor wanted study rewritten
Phase I Recurrent Melanoma trial by Roswell Park Cancer Institute. Stop reason: OTHER/UNKNOWN.
Study was Suspended since 2018; PI decided to terminate.
Phase II Stage I Oral Cavity Squamous Cell Carcinoma trial by Roswell Park Cancer Institute. Stop reason: OPERATIONAL.
low accrual
Phase II Metastatic Colorectal Adenocarcinoma trial by Roswell Park Cancer Institute. Stop reason: OTHER/UNKNOWN.
implementation issues
Phase I Allogeneic Hematopoietic Stem Cell Transplantation Recipient trial by Roswell Park Cancer Institute. Stop reason: OPERATIONAL.
no accrual
Phase II Blasts Under 5 Percent of Peripheral Blood White Cells trial by Roswell Park Cancer Institute. Stop reason: OPERATIONAL.
no accrual
Unknown Recurrent Renal Cell Carcinoma trial by Roswell Park Cancer Institute. Stop reason: OPERATIONAL.
sponsor having financial difficulties
Phase II Lung Non-Squamous Non-Small Cell Carcinoma trial by Roswell Park Cancer Institute. Stop reason: OPERATIONAL.
low accrual
Unknown Healthy, no Evidence of Disease trial by Roswell Park Cancer Institute. Stop reason: OPERATIONAL.
low accrual
Phase II Metastatic Bladder Urothelial Carcinoma trial by Roswell Park Cancer Institute. Stop reason: OPERATIONAL.
no accrual
Phase II Extraocular Extension Melanoma trial by Roswell Park Cancer Institute. Stop reason: OPERATIONAL.
low accrual
Phase I Recurrent Fallopian Tube Carcinoma trial by Roswell Park Cancer Institute. Stop reason: OTHER/UNKNOWN.
production of adjuvant to be used with vaccine was discontinued by sponsor
Phase II Adult Acute Myeloid Leukemia With 11q23 (MLL) Abnormalities trial by Roswell Park Cancer Institute. Stop reason: OPERATIONAL.
low accrual
Phase II Lung Cancer trial by Roswell Park Cancer Institute. Stop reason: EFFICACY/FUTILITY.
lack of efficacy
Phase II Prostate Cancer trial by Roswell Park Cancer Institute. Stop reason: EFFICACY/FUTILITY.
closed due to futility
Phase II Colorectal Cancer trial by Roswell Park Cancer Institute. Stop reason: OPERATIONAL.
Withdrawn due to poor/low accrual
Phase II Recurrent Laryngeal Squamous Cell Carcinoma trial by Roswell Park Cancer Institute. Stop reason: OTHER/UNKNOWN.
Study no longer has an active IDE
Unknown Recurrent Bladder Cancer trial by Roswell Park Cancer Institute. Stop reason: OPERATIONAL.
low accrual
Phase I Prostate Adenocarcinoma trial by Roswell Park Cancer Institute. Stop reason: OPERATIONAL.
difficult to recruit
Unknown Precancerous/Nonmalignant Condition trial by Roswell Park Cancer Institute. Stop reason: OPERATIONAL.
Withdrawn due to low accrual
Phase II Prostate Cancer trial by Roswell Park Cancer Institute. Stop reason: OTHER/UNKNOWN.
sample size is too small to draw a conclusion
Phase II Liver Cancer trial by Roswell Park Cancer Institute. Stop reason: OPERATIONAL.
low accrual
Phase II Pancreatic Cancer trial by Roswell Park Cancer Institute. Stop reason: OTHER/UNKNOWN.
This study was terminated earlier due to a phase III study that showed this drug inferior to sorafenib
Phase I Hodgkin's Lymphoma trial by Roswell Park Cancer Institute. Stop reason: OPERATIONAL.
lack of funding
Phase II Rectal Adenocarcinoma trial by Roswell Park Cancer Institute. Stop reason: OTHER/UNKNOWN.
No stop-reason text available in the compact dataset.
Phase II Leukemia trial by Roswell Park Cancer Institute. Stop reason: OPERATIONAL.
Sponsor withdrew support
Unknown B-cell Chronic Lymphocytic Leukemia trial by Roswell Park Cancer Institute. Stop reason: OTHER/UNKNOWN.
No stop-reason text available in the compact dataset.
Phase I Esophageal Cancer trial by Roswell Park Cancer Institute. Stop reason: OPERATIONAL.
PI left institute
Phase II Waldenström Macroglobulinemia trial by Roswell Park Cancer Institute. Stop reason: OPERATIONAL.
funding was withdrawn
Phase I Myelodysplastic Syndrome trial by Roswell Park Cancer Institute. Stop reason: OPERATIONAL.
Drug provider withdrew support
Phase I Colon Adenocarcinoma trial by Roswell Park Cancer Institute. Stop reason: OPERATIONAL.
drug supply issues
Phase II Acute Myeloid Leukemia With Multilineage Dysplasia Following Myelodysplastic Syndrome trial by Roswell Park Cancer Institute. Stop reason: OTHER/UNKNOWN.
Major revisions needed in study
Phase II Recurrent Squamous Cell Carcinoma of the Lip and Oral Cavity trial by Roswell Park Cancer Institute. Stop reason: OTHER/UNKNOWN.
No stop-reason text available in the compact dataset.
Unknown Head and Neck Cancer trial by Roswell Park Cancer Institute. Stop reason: OPERATIONAL.
Low accrual
Phase I Head and Neck Cancer trial by Roswell Park Cancer Institute. Stop reason: SAFETY.
safety issues
Phase I Adult Solid Neoplasm trial by Roswell Park Cancer Institute. Stop reason: OTHER/UNKNOWN.
Study transferring to INOVA Health
Phase II Colorectal Cancer trial by Roswell Park Cancer Institute. Stop reason: OPERATIONAL.
former PI left institute
Phase I Esophageal Cancer trial by Roswell Park Cancer Institute. Stop reason: OTHER/UNKNOWN.
No stop-reason text available in the compact dataset.
Phase II Prostate Cancer trial by Roswell Park Cancer Institute. Stop reason: EFFICACY/FUTILITY.
Closed for futility
Phase I Duct Cell Adenocarcinoma of the Pancreas trial by Roswell Park Cancer Institute. Stop reason: OPERATIONAL.
Lack of funding
Phase II Gastric Cancer trial by Roswell Park Cancer Institute. Stop reason: OPERATIONAL.
low accrual