Organon and Co clinical trial failures

Review 30 stopped clinical trials from Organon and Co, including disease areas, phases, and classified stop reasons.

This page groups real ClinicalTrials.gov-derived stopped trial records. The strongest added signal is the stop-reason classification: 0 of these records are likely biological failure signals, while the rest may reflect operational, strategic, regulatory, funding, enrollment, or unclear stop reasons.

Total stopped trials30

Likely biological signals0

Shown below30

Dominant stop reasons

OTHER/UNKNOWN: 16
OPERATIONAL: 14

Notable sponsors

Organon and Co: 30

Related phases

Phase III: 16
Phase IV: 10
Phase II: 4

Crawlable stopped-trial records

Open Explore

Showing up to 30 representative records from this slice. Each link opens the trial detail page with source attribution and stop-reason context.

NCT00651807: A Trial to Investigate the Effectiveness and Safety of Org 3236 (Etonogestrel) Tablets in Men With Urinary Complaints Suggestive of a Benign Enlargement of the Prostate (304001)(P05806)

Phase II Benign Prostatic Hyperplasia (BPH) trial by Organon and Co. Stop reason: OPERATIONAL.

Business Reasons

NCT05264506: Contraceptive Efficacy and Safety of NOMAC-E2 Combined Oral Contraceptive

Phase III Contraception trial by Organon and Co. Stop reason: OPERATIONAL.

Sponsor decision to stop the study early and complete all required study close-out activities. This decision was made for business reasons unrelated to safety. None of the pre-specified efficacy endpoints were analyzed.

NCT00092833: Investigational Drug in Patients With Hypercholesterolemia or in Patients With Sitosterolemia (0653-026)(COMPLETED)

Phase III Hypercholesterolemia, Familial trial by Organon and Co. Stop reason: OTHER/UNKNOWN.

No stop-reason text available in the compact dataset.

NCT00651391: Effect of Ezetimibe Plus Simvastatin on Flow-Mediated Brachial Artery Vasoactivity in Subjects With Primary Hypercholesterolemia (Study P03336)

Phase III Hypercholesterolemia trial by Organon and Co. Stop reason: OPERATIONAL.

Slow enrollment

NCT00449111: An Open Label Study to Assess the Efficacy, Safety and Tolerability of COZAAR Plus (Losartan Potassium 50mg/Hydrochlorothiazide 12.5mg) Possibly Titrated up to COZAAR Plus-F (Losartan Potassium 100mg/Hydrochlorothiazide 25mg) in Patients With Essential Hypertension (0954A-325)

Phase III Hypertension trial by Organon and Co. Stop reason: OTHER/UNKNOWN.

No stop-reason text available in the compact dataset.

NCT00751166: A Comparative Double-blind, Double-dummy Study of Desloratadine (DL) 5 mg Once Daily, Cetirizine 10 mg Once Daily, and Placebo Once Daily in Patients With Chronic Idiopathic Urticaria (Study P03736)

Phase IV Urticaria trial by Organon and Co. Stop reason: OTHER/UNKNOWN.

Study could not be re-supplied with study medication in a timely manner.

NCT00395603: Vytorin Treating Uncontrolled Lipids (VyTUL) Study (0653A-122)

Phase III Cardiovascular Diseases trial by Organon and Co. Stop reason: OPERATIONAL.

This study was terminated early due to poor recruitment.

NCT00651378: Switching to Rosuvastatin Versus Adding Ezetimibe to Atorvastatin Versus Doubling the Dose of Atorvastatin in Patients With Hypercholesterolemia and Risk Factors (P03708)

Phase IV Hypercholesterolemia trial by Organon and Co. Stop reason: OPERATIONAL.

Slow enrollment \[HIGH SCREEN FAILURE RATE\]

NCT01656434: Study of the Contraceptive Efficacy and Safety of a NOMAC-E2 Combined Oral Contraceptive (COC)(P06448)

Phase III Contraception trial by Organon and Co. Stop reason: OPERATIONAL.

Business reasons

NCT00447603: A Study of Losartan Compared to Losartan/HCTZ in Pediatric Patients With Hypertension (0954A-327)

Phase III Hypertension trial by Organon and Co. Stop reason: OTHER/UNKNOWN.

Achieving site readiness and enrolling the trial within a reasonable time

NCT00697255: A Phase 2 Trial to Evaluate if Corifollitropin Alfa (Org 36286), Followed by a Low Daily Dose of hCG or Recombinant FSH Can Induce Monofollicular Growth in Women With WHO Group II Anovulatory Infertility (P05693)

Phase II Ovulation Induction trial by Organon and Co. Stop reason: OTHER/UNKNOWN.

No stop-reason text available in the compact dataset.

NCT02668783: Efficacy and Safety of Etonogestrel + 17β-Estradiol Vaginal Ring (MK-8342B) in Women With Primary Dysmenorrhea (With Optional Extension) (MK-8342B-059)

Phase III Moderate to Severe Primary Dysmenorrhea trial by Organon and Co. Stop reason: OPERATIONAL.

Study terminated by Sponsor as a result of a business decision to discontinue the development program for MK-8342B for reasons unrelated to safety or efficacy.

NCT02668822: Efficacy and Safety of Etonogestrel + 17β-Estradiol Vaginal Ring (MK-8342B) in the Treatment of Women With Primary Dysmenorrhea (MK-8342B-060)

Phase III Dysmenorrhea trial by Organon and Co. Stop reason: OPERATIONAL.

Study terminated by Sponsor as a result of a business decision to discontinue the development program for MK-8342B for reasons unrelated to safety or efficacy.

NCT00687531: Clinical Trial to Assess Efficacy, Safety, Treatment Adherence and Quality of Life Impact of Mometasone Furoate in Asthmatic Patients (Study P04879)(TERMINATED)

Phase IV Asthma trial by Organon and Co. Stop reason: OTHER/UNKNOWN.

No stop-reason text available in the compact dataset.

NCT00739050: Effect of Simvastatin on Endothelial Function in Premenopausal Women With Systemic Lupus Erythematosus (0733-271)(TERMINATED)

Phase IV Systemic Lupus Erythematosus trial by Organon and Co. Stop reason: OTHER/UNKNOWN.

No stop-reason text available in the compact dataset.

NCT00423176: The Study of Nasonex® Compared With Placebo for the Relief of Symptoms Associated With Acute Bacterial Sinusitis When Used With Antibiotics (Study P04824AM3)

Phase III Sinusitis trial by Organon and Co. Stop reason: OTHER/UNKNOWN.

Based on business priorities. Not related to any safety or efficacy issue \& took place before data were unblinded or analyzed

NCT02616146: Efficacy and Safety of Etonogestrel + 17β-Estradiol Vaginal Ring and Levonorgestrel-Ethinyl Estradiol Combined Oral Contraceptive in Adult Women at Risk for Pregnancy (MK-8342B-062)

Phase III Contraception trial by Organon and Co. Stop reason: OPERATIONAL.

Study terminated by Sponsor as a result of a business decision to discontinue the development program for MK-8342B for reasons unrelated to safety or efficacy.

NCT02524288: Efficacy and Safety of Etonogestrel + 17β-Estradiol Vaginal Ring in Women at Risk for Pregnancy (MK-8342B-061)

Phase III Contraception trial by Organon and Co. Stop reason: OPERATIONAL.

This study was terminated by the Sponsor due to a business decision to discontinue product development for reasons unrelated to safety or efficacy outcomes.

NCT01429168: A Study of Etoricoxib in Participants With Osteoarthritis Not Responding to Analgesic Drugs (MK-0663-142)

Phase IV Osteoarthritis trial by Organon and Co. Stop reason: OTHER/UNKNOWN.

No stop-reason text available in the compact dataset.

NCT01587235: A Study to Evaluate the Efficacy and Safety of Vytorin Versus Standard Treatment of Other Statins in Moderate, Moderately High and High Risk Participants (MK-0653A-406)

Phase IV Dyslipidemia trial by Organon and Co. Stop reason: OTHER/UNKNOWN.

No stop-reason text available in the compact dataset.

NCT00553891: Placebo-controlled Trial With Nasonex for Nasal Obstruction Secondary to Adenoids Hypertrophy in Children (P04367)(TERMINATED)

Phase IV Nasal Obstruction trial by Organon and Co. Stop reason: OPERATIONAL.

No enrollment because of war in the study country.

NCT00651014: Ezetimibe Plus Simvastatin Versus Simvastatin in Patients With Hypercholesterolemia and Coronary Risk Factors (P03405)

Phase IV Hypercholesterolemia trial by Organon and Co. Stop reason: OPERATIONAL.

slow subject recruitment and lack of medical and scientific merit due to change in new standard of therapy during that same period.