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OHSU Knight Cancer Institute clinical trial failures
Review 48 stopped clinical trials from OHSU Knight Cancer Institute, including disease areas, phases, and classified stop reasons.
This page groups real ClinicalTrials.gov-derived stopped trial records. The strongest added signal is the stop-reason classification: 2 of these records are likely biological failure signals, while the rest may reflect operational, strategic, regulatory, funding, enrollment, or unclear stop reasons.
Dominant stop reasons
- OPERATIONAL
- 31
- OTHER/UNKNOWN
- 15
- SAFETY
- 2
Notable sponsors
- OHSU Knight Cancer Institute
- 48
Related phases
- Phase II
- 27
- Phase I
- 10
- Early Phase I
- 5
- Unknown
- 5
- Phase III
- 1
Crawlable stopped-trial records
Open ExploreShowing up to 48 representative records from this slice. Each link opens the trial detail page with source attribution and stop-reason context.
Phase II Liver and Intrahepatic Bile Duct Carcinoma trial by OHSU Knight Cancer Institute. Stop reason: OTHER/UNKNOWN.
change in standard-of-care systemic therapy
Phase II Advanced Breast Carcinoma trial by OHSU Knight Cancer Institute. Stop reason: OTHER/UNKNOWN.
Loss of support.
Unknown Cutaneous Melanoma trial by OHSU Knight Cancer Institute. Stop reason: OPERATIONAL.
The study did not meet its accrual goals due to the departure of study personnel. Study team opted for a study closure due to loss of key personnel.
Phase II High Risk Prostate Carcinoma trial by OHSU Knight Cancer Institute. Stop reason: OPERATIONAL.
Loss of funding
Phase II Glioblastoma trial by OHSU Knight Cancer Institute. Stop reason: OTHER/UNKNOWN.
Principal investigator transition
Phase II Leukemia trial by OHSU Knight Cancer Institute. Stop reason: SAFETY.
No stop-reason text available in the compact dataset.
Unknown Familial Pancreatic Cancer trial by OHSU Knight Cancer Institute. Stop reason: OPERATIONAL.
Loss of funding
Phase II Pancreatic Carcinoma trial by OHSU Knight Cancer Institute. Stop reason: OPERATIONAL.
low enrollment
Phase II Infection trial by OHSU Knight Cancer Institute. Stop reason: OTHER/UNKNOWN.
competing study at site
Phase I Prostate Cancer trial by OHSU Knight Cancer Institute. Stop reason: OPERATIONAL.
Funding withdrawal
Phase II Locally Advanced Pancreatic Ductal Adenocarcinoma trial by OHSU Knight Cancer Institute. Stop reason: OTHER/UNKNOWN.
Sponsor withdrawal
Unknown Breast Carcinoma trial by OHSU Knight Cancer Institute. Stop reason: OTHER/UNKNOWN.
study staff transition
Phase I Accelerated Phase Chronic Myelogenous Leukemia, BCR-ABL1 Positive trial by OHSU Knight Cancer Institute. Stop reason: OPERATIONAL.
Low accrual
Phase II Lymphoma trial by OHSU Knight Cancer Institute. Stop reason: OPERATIONAL.
Insufficient accrual rate
Early Phase I Advanced Breast Carcinoma trial by OHSU Knight Cancer Institute. Stop reason: OTHER/UNKNOWN.
Withdrawn due to a change in therapeutic interventions.
Phase II Metastatic Malignant Neoplasm in the Brain trial by OHSU Knight Cancer Institute. Stop reason: OPERATIONAL.
Loss of funding
Phase II Brain and Central Nervous System Tumors trial by OHSU Knight Cancer Institute. Stop reason: OPERATIONAL.
Lack of accrual
Early Phase I Advanced Fallopian Tube Carcinoma trial by OHSU Knight Cancer Institute. Stop reason: OTHER/UNKNOWN.
PI discretion
Phase II Leukemia trial by OHSU Knight Cancer Institute. Stop reason: OTHER/UNKNOWN.
Increased rate of bacterial infections
Phase II Brain Neoplasms trial by OHSU Knight Cancer Institute. Stop reason: OTHER/UNKNOWN.
AMAG not continuing with Combidex, the study drug
Phase II BCLC Stage B Hepatocellular Carcinoma trial by OHSU Knight Cancer Institute. Stop reason: OPERATIONAL.
Due to inadequate funding. This trial may open as a new clinical trial at a later date, pending drug approval.
Unknown Breast Cancer trial by OHSU Knight Cancer Institute. Stop reason: OPERATIONAL.
Low patient enrollment and no clinical findings.
Phase II Lung Carcinoma Metastatic in the Brain trial by OHSU Knight Cancer Institute. Stop reason: OPERATIONAL.
Low accrual
Phase II Recurrent Acute Myeloid Leukemia trial by OHSU Knight Cancer Institute. Stop reason: OPERATIONAL.
Not enough enrollment to determine efficacy
Phase II Brain Neoplasm trial by OHSU Knight Cancer Institute. Stop reason: OPERATIONAL.
No enrollments
Phase II Acute Myeloid Leukemia Arising From Previous Myelodysplastic Syndrome trial by OHSU Knight Cancer Institute. Stop reason: OPERATIONAL.
Unable to recruit enough eligible subjects
Early Phase I Stage IIB Esophageal Cancer AJCC v7 trial by OHSU Knight Cancer Institute. Stop reason: OPERATIONAL.
Inadequate enrollment
Early Phase I Locally Advanced Rectal Carcinoma trial by OHSU Knight Cancer Institute. Stop reason: OPERATIONAL.
low accrual
Phase II Hematopoietic and Lymphoid Cell Neoplasm trial by OHSU Knight Cancer Institute. Stop reason: OTHER/UNKNOWN.
limited resources
Early Phase I Stage II Adult Soft Tissue Sarcoma trial by OHSU Knight Cancer Institute. Stop reason: OPERATIONAL.
Funding expired
Phase I Lymphoma trial by OHSU Knight Cancer Institute. Stop reason: OPERATIONAL.
Funding ended when only one subject enrolled and subject withdrew early.
Phase II Hormone-Resistant Prostate Cancer trial by OHSU Knight Cancer Institute. Stop reason: OPERATIONAL.
low enrollment
Phase II Breast Cancer trial by OHSU Knight Cancer Institute. Stop reason: OPERATIONAL.
Sponsor pulled funding and low accrual
Phase II Chronic Myeloproliferative Disorders trial by OHSU Knight Cancer Institute. Stop reason: OTHER/UNKNOWN.
No stop-reason text available in the compact dataset.
Phase II Leukemia trial by OHSU Knight Cancer Institute. Stop reason: OPERATIONAL.
Low enrollment
Phase I Breakthrough Nausea and Vomiting trial by OHSU Knight Cancer Institute. Stop reason: OPERATIONAL.
Drug contract timelines and inadequate enrollment
Phase III Breast Cancer trial by OHSU Knight Cancer Institute. Stop reason: OTHER/UNKNOWN.
No stop-reason text available in the compact dataset.
Unknown Anemia trial by OHSU Knight Cancer Institute. Stop reason: OPERATIONAL.
Sponsor discontinued funding of the study
Phase II Prostate Cancer trial by OHSU Knight Cancer Institute. Stop reason: OPERATIONAL.
Drug supplier stopped funding due to loss of study drug (docetaxel) patent.
Phase I Adenocarcinoma of the Prostate trial by OHSU Knight Cancer Institute. Stop reason: OPERATIONAL.
After enrollment of the first 3 subjects, an interim assessment was conducted. Comparing DBS sampling to plasma PK levels yielded unconvincing results.
Phase II Prostate Cancer trial by OHSU Knight Cancer Institute. Stop reason: OTHER/UNKNOWN.
No stop-reason text available in the compact dataset.
Phase II Adenocarcinoma of the Prostate trial by OHSU Knight Cancer Institute. Stop reason: SAFETY.
Drug safety concerns
Phase I Brain and Central Nervous System Tumors trial by OHSU Knight Cancer Institute. Stop reason: OPERATIONAL.
after original approval, IRB closed enrollment; major revisions required to re-open.
Phase I Ovarian Carcinoma, Stage 3 or 4 trial by OHSU Knight Cancer Institute. Stop reason: OPERATIONAL.
No funding was available for the cost of the IV N-acetylcysteine (NAC).
Phase I Bone Marrow Suppression trial by OHSU Knight Cancer Institute. Stop reason: OPERATIONAL.
OHSU IRB closed study to further enrollment 2/17/2006
Phase I Brain Neoplasms trial by OHSU Knight Cancer Institute. Stop reason: OPERATIONAL.
Inadequate enrollment
Phase I Brain and Central Nervous System Tumors trial by OHSU Knight Cancer Institute. Stop reason: OPERATIONAL.
Other competing clinical trials affecting enrollment
Phase II Leukemia trial by OHSU Knight Cancer Institute. Stop reason: OTHER/UNKNOWN.
No stop-reason text available in the compact dataset.