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Medical College of Wisconsin clinical trial failures
Review 41 stopped clinical trials from Medical College of Wisconsin, including disease areas, phases, and classified stop reasons.
This page groups real ClinicalTrials.gov-derived stopped trial records. The strongest added signal is the stop-reason classification: 2 of these records are likely biological failure signals, while the rest may reflect operational, strategic, regulatory, funding, enrollment, or unclear stop reasons.
Dominant stop reasons
- OPERATIONAL
- 27
- OTHER/UNKNOWN
- 11
- EFFICACY/FUTILITY
- 1
- REGULATORY
- 1
- SAFETY
- 1
Notable sponsors
- Medical College of Wisconsin
- 41
Related phases
- Phase I
- 15
- Phase II
- 10
- Phase IV
- 6
- Unknown
- 5
- Phase III
- 4
Crawlable stopped-trial records
Open ExploreShowing up to 41 representative records from this slice. Each link opens the trial detail page with source attribution and stop-reason context.
Phase I Brain Metastases trial by Medical College of Wisconsin. Stop reason: OPERATIONAL.
Study never started.
Phase II Acute Myeloid Leukemia trial by Medical College of Wisconsin. Stop reason: OPERATIONAL.
No longer have funding support to complete the pharmacogenetics component.
Phase I Acute Lymphoblastic Leukemia, in Relapse trial by Medical College of Wisconsin. Stop reason: OPERATIONAL.
Low accrual
Phase II Prostate Cancer trial by Medical College of Wisconsin. Stop reason: EFFICACY/FUTILITY.
futility and drug supplier in favor of new metastatic protocol.
Phase I Pancreas Adenocarcinoma trial by Medical College of Wisconsin. Stop reason: OPERATIONAL.
The pharmaceutical funder pulled funding and no longer plans to develop the drug further.
Phase IV Rib Fractures trial by Medical College of Wisconsin. Stop reason: OPERATIONAL.
Poor Enrollment
Phase I Squamous Cell Carcinoma of the Oral Cavity trial by Medical College of Wisconsin. Stop reason: OTHER/UNKNOWN.
Study abandoned.
Phase II Refractory Multiple Myeloma trial by Medical College of Wisconsin. Stop reason: OPERATIONAL.
Low enrollment.
Phase I B-cell Non Hodgkin Lymphoma trial by Medical College of Wisconsin. Stop reason: REGULATORY.
Treated four patients: 2 at a dose of 1x10\^6 cells/kg and 2 ad at dose of 2.5x10\^6 cells/kg. All four patients had no in-vivo expansion and no meaningful response to therapy. At this point per FDA guidance we will not be treating more patients.
Phase I Relapsed Adult AML trial by Medical College of Wisconsin. Stop reason: OPERATIONAL.
Sponsor withdrew support.
Phase I Acute Myelogenous Leukemia trial by Medical College of Wisconsin. Stop reason: OTHER/UNKNOWN.
Takeda P3001 study didn't meet primary endpoint of improvement in event-free survival. There is no regulatory path forward for pevonedistat.
Phase IV Cardiac Amyloidosis trial by Medical College of Wisconsin. Stop reason: OPERATIONAL.
slow recruitment.
Phase II Recurrent Grade 1 Follicular Lymphoma trial by Medical College of Wisconsin. Stop reason: OPERATIONAL.
lower than anticipated accrual
Phase III Leukemia, Myelocytic, Acute trial by Medical College of Wisconsin. Stop reason: OPERATIONAL.
Accrual terminated as recommended by the data and safety monitoring board.
Phase IV DeQuervain's Tenosynovitis trial by Medical College of Wisconsin. Stop reason: OTHER/UNKNOWN.
not enough patient data
Phase I Solid Tumor trial by Medical College of Wisconsin. Stop reason: OPERATIONAL.
Funding and PI leaving institution
Early Phase I Transgenderism trial by Medical College of Wisconsin. Stop reason: OTHER/UNKNOWN.
per MCW IRB
Phase II Patent Ductus Arteriosus (PDA) trial by Medical College of Wisconsin. Stop reason: OPERATIONAL.
Inability to recruit patients
Phase IV Leukemia, Myeloid, Acute trial by Medical College of Wisconsin. Stop reason: OPERATIONAL.
Low accrual
Phase I Acute Leukemia trial by Medical College of Wisconsin. Stop reason: OPERATIONAL.
Poor accrual and loss of funding.
Phase III Ulcerative Colitis trial by Medical College of Wisconsin. Stop reason: OPERATIONAL.
insufficient enrollment
Phase I Refractory Multiple Myeloma trial by Medical College of Wisconsin. Stop reason: OPERATIONAL.
Terminated for lack of funding.
Phase II Delirium trial by Medical College of Wisconsin. Stop reason: OTHER/UNKNOWN.
Closed due to inability to enroll
Phase II Granulomatous and Lymphocytic Interstitial Lung Disease trial by Medical College of Wisconsin. Stop reason: OPERATIONAL.
No funding for study.
Phase III Oral Mucositis trial by Medical College of Wisconsin. Stop reason: OPERATIONAL.
Lack of funding
Phase II Leukemia, Acute Lymphoblastic trial by Medical College of Wisconsin. Stop reason: OPERATIONAL.
Low accrual
Phase I Acute Graft Versus Host Disease trial by Medical College of Wisconsin. Stop reason: SAFETY.
The DSMB felt the risks of the study now outweighed the potential benefits.
Phase IV Feeding Behaviors trial by Medical College of Wisconsin. Stop reason: OPERATIONAL.
Unable to enroll adequate participants
Unknown Ventral Hernia trial by Medical College of Wisconsin. Stop reason: OPERATIONAL.
Manufacturer of Alvimopam closed the study due to low enrollment.
Unknown High Model for End-Stage Liver Disease (MELD) Score trial by Medical College of Wisconsin. Stop reason: OPERATIONAL.
funding was withdrawn
Phase III Eosinophilic Esophagitis trial by Medical College of Wisconsin. Stop reason: OTHER/UNKNOWN.
No stop-reason text available in the compact dataset.
Phase I Metastatic Pancreatic Cancer trial by Medical College of Wisconsin. Stop reason: OPERATIONAL.
Request to close per funding sponsor. Site not moving forward with trial.
Unknown Atopic Dermatitis trial by Medical College of Wisconsin. Stop reason: OPERATIONAL.
Not meeting enrollment goals.
Unknown Congenital Heart Defect trial by Medical College of Wisconsin. Stop reason: OPERATIONAL.
Inadequate patient enrollment
Phase I Scleroderma trial by Medical College of Wisconsin. Stop reason: OTHER/UNKNOWN.
Unable to obtain IRB approval at all sites
Phase IV Acute Pain trial by Medical College of Wisconsin. Stop reason: OPERATIONAL.
Lack of Funding
Phase II Leukemia, Lymphocytic, Acute trial by Medical College of Wisconsin. Stop reason: OPERATIONAL.
Only one patient was enrolled. Due to low accrual study was terminated
Phase I Colorectal Cancer trial by Medical College of Wisconsin. Stop reason: OTHER/UNKNOWN.
Investigator has left institution
Phase II Traumatic Brain Injury trial by Medical College of Wisconsin. Stop reason: OTHER/UNKNOWN.
PI has left institution
Phase I Functional Abdominal Pain trial by Medical College of Wisconsin. Stop reason: OTHER/UNKNOWN.
PI has left institution
Unknown Patients Undergoing Screening or Surveillance Colonoscopy trial by Medical College of Wisconsin. Stop reason: OTHER/UNKNOWN.
Protocol issues. Modifications potentially will be undertaken and resubmitted to IRB