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Indiana University clinical trial failures
Review 60 stopped clinical trials from Indiana University, including disease areas, phases, and classified stop reasons.
This page groups real ClinicalTrials.gov-derived stopped trial records. The strongest added signal is the stop-reason classification: 3 of these records are likely biological failure signals, while the rest may reflect operational, strategic, regulatory, funding, enrollment, or unclear stop reasons.
Dominant stop reasons
- OPERATIONAL
- 36
- OTHER/UNKNOWN
- 19
- REGULATORY
- 2
- SAFETY
- 2
- EFFICACY/FUTILITY
- 1
Notable sponsors
- Indiana University
- 60
Related phases
- Phase II
- 22
- Phase IV
- 14
- Phase I
- 11
- Unknown
- 8
- Phase III
- 5
Crawlable stopped-trial records
Open ExploreShowing up to 60 representative records from this slice. Each link opens the trial detail page with source attribution and stop-reason context.
Phase IV Dental Extraction trial by Indiana University. Stop reason: OPERATIONAL.
No one was enrolled to date and the sponsor requested the study be withdrawn
Phase I Surgery trial by Indiana University. Stop reason: OTHER/UNKNOWN.
study specific patients are now scheduled at another hospital for this procedure
Phase I Sickle Cell Disease trial by Indiana University. Stop reason: OPERATIONAL.
low accrual
Phase I Necrotizing Enterocolitis trial by Indiana University. Stop reason: OTHER/UNKNOWN.
Project plan was abandoned.
Phase II Anemia, Iron Deficiency trial by Indiana University. Stop reason: OPERATIONAL.
Difficulty recruiting participants
Phase IV Symptomatic Irreversible Pulpitis trial by Indiana University. Stop reason: OTHER/UNKNOWN.
Student PI is preparing for graduation and cannot complete the study as planned.
Phase II Alcohol Use Disorder trial by Indiana University. Stop reason: OTHER/UNKNOWN.
Due to complications delaying the availability of the intranasal oxytocin and IV alcohol solutions needed for this project, we were unable to complete subjects in the self-administration arm of this study.
Phase III Preterm Premature Ruptured Membranes trial by Indiana University. Stop reason: REGULATORY.
Terminated before starting due to need for IND determined by FDA.
Phase IV Renal Malignant Tumor trial by Indiana University. Stop reason: OPERATIONAL.
Study stopped due to staffing issues that impacted ability to recruit.
Phase II NSCLC, Stage III trial by Indiana University. Stop reason: OTHER/UNKNOWN.
Unable to identify patients who meet eligibility requirements of tissue needed for analysis.
Phase II Heart Failure trial by Indiana University. Stop reason: OPERATIONAL.
COVID-19 pandemic. Initially had planned to resume study, but ultimately decided to close.
Phase IV MRSA trial by Indiana University. Stop reason: OPERATIONAL.
Unable to recruit all planned participants prior to end of funding
Phase I Bone Marrow Transplant Complications trial by Indiana University. Stop reason: OTHER/UNKNOWN.
PI has left IU with no plan to initiate study at IU
Phase III Thoracotomy trial by Indiana University. Stop reason: OTHER/UNKNOWN.
Study terminated to to shortage if study supplies for epidurals and most enrolled has study deviations due to not receiving correct post study drug assignments.
Phase IV Exercise-induced Arterial Hypoxemia trial by Indiana University. Stop reason: OPERATIONAL.
The recruited population was no longer made available to participate in the study.
Phase II NAFLD trial by Indiana University. Stop reason: OPERATIONAL.
lack of coordinator resources and lack of access to study resources during and due to the COVID pandemic
Phase III Kidney Failure trial by Indiana University. Stop reason: OTHER/UNKNOWN.
Study was larger than expected and became a burden to faculty and staff resources.
Phase III Kidney Failure trial by Indiana University. Stop reason: OTHER/UNKNOWN.
Study was larger than expected and became a burden to faculty and staff resources.
Phase II Hypertension trial by Indiana University. Stop reason: OTHER/UNKNOWN.
No stop-reason text available in the compact dataset.
Phase II Glioblastoma Multiforme trial by Indiana University. Stop reason: OPERATIONAL.
Failure to meet accrual goals.
Phase II Gastroparesis trial by Indiana University. Stop reason: OTHER/UNKNOWN.
Abandoned due to limited resources
Phase IV Gastroschisis trial by Indiana University. Stop reason: OPERATIONAL.
Unable to sufficiently recruit candidates
Phase IV Surgery trial by Indiana University. Stop reason: OPERATIONAL.
Lack of enrollment/lack of potential subjects fitting criteria
Phase IV Kidney Stone trial by Indiana University. Stop reason: OTHER/UNKNOWN.
Drop out from surgeons from 3 to 1. It will take too long to feasibly accrue with only one provider.
Phase II Neurofibroma, Plexiform trial by Indiana University. Stop reason: OPERATIONAL.
Enrollment not feasible
Phase I Postoperative Pain trial by Indiana University. Stop reason: OPERATIONAL.
Lack of funding
Phase IV Anesthesia, Pediatrics, Surgery trial by Indiana University. Stop reason: OPERATIONAL.
PI has left Riley Anesthesia. Lack of staff for continued recruitment
Phase I Osteoporosis trial by Indiana University. Stop reason: OPERATIONAL.
was not funded
Unknown Inflammatory Bowel Disease trial by Indiana University. Stop reason: OPERATIONAL.
physician decision to stop study early due to low enrollment
Phase II Pancreatic Cancer trial by Indiana University. Stop reason: OTHER/UNKNOWN.
Study is being abandoned.
Unknown Laryngopharyngeal Reflux trial by Indiana University. Stop reason: OPERATIONAL.
Principal investigator left institution
Phase IV Liver Biopsy trial by Indiana University. Stop reason: OPERATIONAL.
Insufficient patient recruitment. Data lost following departure of key personnel
Phase I Pre-diabetes trial by Indiana University. Stop reason: OTHER/UNKNOWN.
Preliminary results indicated no measurable benefit.
Phase II Schizophrenia trial by Indiana University. Stop reason: OPERATIONAL.
Funding ended
Phase II Cerebral Vasospasm trial by Indiana University. Stop reason: OPERATIONAL.
Completion not feasible due to lack of eligible subjects.
Unknown Renal Cell Carcinoma trial by Indiana University. Stop reason: OPERATIONAL.
No further funding
Phase II Borderline Personality Disorder trial by Indiana University. Stop reason: OPERATIONAL.
Funding ended
Phase II Pain, Postoperative trial by Indiana University. Stop reason: REGULATORY.
FDA IND was not obtained
Phase IV Thrombosis trial by Indiana University. Stop reason: OPERATIONAL.
Slow enrollment
Phase II Neurofibromatosis trial by Indiana University. Stop reason: OTHER/UNKNOWN.
1 patient died of uncertain cause but possibly related to drug.
Phase II Acute Heart Failure trial by Indiana University. Stop reason: OPERATIONAL.
Study was not funded
Phase II Vincristine Induced Neuropathy trial by Indiana University. Stop reason: OTHER/UNKNOWN.
Drug availability
Unknown Dementia trial by Indiana University. Stop reason: OPERATIONAL.
Low study accrual caused the study to be ended early.
Phase I Polycystic Ovary Syndrome trial by Indiana University. Stop reason: OPERATIONAL.
The PI left Indiana University. The findings served as preliminary data for a recently awarded NIH R01 grant.
Phase IV Adult Intracranial Neoplasm trial by Indiana University. Stop reason: OPERATIONAL.
Lack of enrollment. No new subjects had been enrolled for nearly a year.
Phase II Osteoarthritis trial by Indiana University. Stop reason: OPERATIONAL.
We were unable to enroll any patients into the study.
Phase IV Chronic Kidney Disease trial by Indiana University. Stop reason: SAFETY.
Terminated by the DSMB based on low chance of finding differences in mGFR slopes, but higher risk of serious adverse events in the IV iron group (aIRR = 1.60)
Phase IV Intracranial Aneurysms trial by Indiana University. Stop reason: OPERATIONAL.
Lack of enrollment - since the start of the study in 2013, only 17 subjects have consented. Of those, only 8 completed the study.
Phase II Pancreas Neoplasms trial by Indiana University. Stop reason: OPERATIONAL.
Lack of funding and personnel to conduct study.
Phase I Morbid Obesity trial by Indiana University. Stop reason: OPERATIONAL.
Funding withdrawn; study closed due to lack of accrual.
Phase III Hemodialysis trial by Indiana University. Stop reason: SAFETY.
Stopped by data safety monitoring board
Unknown Exercise-Induced Bronchospasm trial by Indiana University. Stop reason: OTHER/UNKNOWN.
No stop-reason text available in the compact dataset.
Phase II Pulmonary Hypertension trial by Indiana University. Stop reason: OPERATIONAL.
Unable to enroll subjects
Unknown Coronary Artery Disease trial by Indiana University. Stop reason: OPERATIONAL.
Slower than anticipated enrollment for pilot study.
Phase I Hepatocellular Carcinoma trial by Indiana University. Stop reason: EFFICACY/FUTILITY.
Treatment was ineffective
Phase II Arthritis, Rheumatoid trial by Indiana University. Stop reason: OTHER/UNKNOWN.
Dr. Levy terminated from IU in December 2009. Indiana University has no record that this study was initiated prior to his termination.
Unknown Ductal Carcinoma in Situ trial by Indiana University. Stop reason: OPERATIONAL.
Terminated due to low accrual
Phase II Adult Central Nervous System Germ Cell Tumor trial by Indiana University. Stop reason: OPERATIONAL.
Due to Low Accrual
Phase I Hepatocellular Carcinoma trial by Indiana University. Stop reason: OTHER/UNKNOWN.
Trial had no patients accrued while open
Unknown Chronic Acalculous Cholecystitis trial by Indiana University. Stop reason: OPERATIONAL.
Study was never initiated due to lack of funding support.