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Icahn School of Medicine at Mount Sinai clinical trial failures
Review 51 stopped clinical trials from Icahn School of Medicine at Mount Sinai, including disease areas, phases, and classified stop reasons.
This page groups real ClinicalTrials.gov-derived stopped trial records. The strongest added signal is the stop-reason classification: 7 of these records are likely biological failure signals, while the rest may reflect operational, strategic, regulatory, funding, enrollment, or unclear stop reasons.
Dominant stop reasons
- OPERATIONAL
- 25
- OTHER/UNKNOWN
- 18
- EFFICACY/FUTILITY
- 6
- REGULATORY
- 1
- SAFETY
- 1
Notable sponsors
- Icahn School of Medicine at Mount Sinai
- 51
Related phases
- Phase II
- 24
- Phase IV
- 14
- Phase III
- 5
- Unknown
- 5
- Phase I
- 3
Crawlable stopped-trial records
Open ExploreShowing up to 51 representative records from this slice. Each link opens the trial detail page with source attribution and stop-reason context.
Unknown Borderline Personality Disorder trial by Icahn School of Medicine at Mount Sinai. Stop reason: OPERATIONAL.
Study was halted during COVID pandemic. However, PI is currently reconnecting with a compounding pharmacy to re-establish supply of the oxytocin and updating cost estimates. We are hoping to resume the pilot work with oxytocin once it is clarified.
Phase IV Migraine Headaches trial by Icahn School of Medicine at Mount Sinai. Stop reason: OTHER/UNKNOWN.
Study closing at current site. Study to start as new at different site.
Phase II Pyoderma Gangrenosum trial by Icahn School of Medicine at Mount Sinai. Stop reason: OPERATIONAL.
The funding sponsor terminated our study and will conduct a multicenter national study in its place.
Phase III Acne Keloidalis Nuchae trial by Icahn School of Medicine at Mount Sinai. Stop reason: EFFICACY/FUTILITY.
Interim analysis did not show any significant differences between groups
Phase II Neoplasm trial by Icahn School of Medicine at Mount Sinai. Stop reason: OTHER/UNKNOWN.
NX Development Corporation closed the trial
Phase II CTCL trial by Icahn School of Medicine at Mount Sinai. Stop reason: OTHER/UNKNOWN.
No significant improvement in disease as graded by our assessments.
Phase III Pleural Disease trial by Icahn School of Medicine at Mount Sinai. Stop reason: OTHER/UNKNOWN.
interim, lack of obvious benefit
Phase II Seborrheic Dermatitis trial by Icahn School of Medicine at Mount Sinai. Stop reason: EFFICACY/FUTILITY.
The study ended early because interim analysis showed no significant difference between the active and placebo arms.
Phase IV Mild Autonomous Cortisol Excess trial by Icahn School of Medicine at Mount Sinai. Stop reason: OPERATIONAL.
Difficulty recruiting patients
Phase II Papulopustular Rosacea trial by Icahn School of Medicine at Mount Sinai. Stop reason: OPERATIONAL.
This study is being closed due to sponsor withdrawal of funding and support.
Phase II Dysmenorrhea trial by Icahn School of Medicine at Mount Sinai. Stop reason: OTHER/UNKNOWN.
Study withdrawn due to inability to determine path forward regarding study design between sponsor and institutional staff.
Phase II Thrombotic Thrombocytopenic Purpura trial by Icahn School of Medicine at Mount Sinai. Stop reason: OPERATIONAL.
low enrollment
Phase IV Lumbar Radiculopathy trial by Icahn School of Medicine at Mount Sinai. Stop reason: OPERATIONAL.
recruitment difficulty
Phase II Autism Spectrum Disorder trial by Icahn School of Medicine at Mount Sinai. Stop reason: OTHER/UNKNOWN.
Decision made to terminate due to difficulty in procurement of adequate supply of treatment drug. Decision made on April 2023 to terminate study.
Phase II Locally Advanced Breast Cancer trial by Icahn School of Medicine at Mount Sinai. Stop reason: SAFETY.
Data Safety Monitoring Board is in agreement with the study findings so far and the stopping rule has been met, which suspends the study treatment arms in March 2021.
Phase II Obesity trial by Icahn School of Medicine at Mount Sinai. Stop reason: OTHER/UNKNOWN.
No stop-reason text available in the compact dataset.
Phase III Gynecomastia trial by Icahn School of Medicine at Mount Sinai. Stop reason: OPERATIONAL.
Unable to recruit patients
Phase II Human Papillomavirus (HPV) trial by Icahn School of Medicine at Mount Sinai. Stop reason: OTHER/UNKNOWN.
lack of eligible participants due to change in study criterias
Phase IV Hypertension in Pregnancy trial by Icahn School of Medicine at Mount Sinai. Stop reason: OPERATIONAL.
Low enrollment
Phase III Mesenchymal Stromal Cells trial by Icahn School of Medicine at Mount Sinai. Stop reason: EFFICACY/FUTILITY.
At 3d interim analysis, randomization, but not follow-up, was halted by the DSMB due to low predictive probability of achieving postulated mortality benefit (pre-specified 42.5% relative mortality reduction) were the trial to complete randomization.
Phase II Suicidal Ideation trial by Icahn School of Medicine at Mount Sinai. Stop reason: OTHER/UNKNOWN.
PI leaving institution
Phase I Breast Cancer trial by Icahn School of Medicine at Mount Sinai. Stop reason: OPERATIONAL.
low accrual rate
Phase IV Cognitive Performance trial by Icahn School of Medicine at Mount Sinai. Stop reason: OPERATIONAL.
Low enrollment
Phase II Alopecia Areata trial by Icahn School of Medicine at Mount Sinai. Stop reason: OPERATIONAL.
low enrollment
Phase IV Psoriasis, Skin or Nails trial by Icahn School of Medicine at Mount Sinai. Stop reason: OTHER/UNKNOWN.
Lack of subjects
Phase II SARS-CoV-2 trial by Icahn School of Medicine at Mount Sinai. Stop reason: OPERATIONAL.
Due to the number of competing trials at their site, the study team has closed enrollment and withdrawn this trial.
Phase II High Risk Smoldering Multiple Myeloma trial by Icahn School of Medicine at Mount Sinai. Stop reason: OPERATIONAL.
Poor accrual and risk/benefit ratio.
Phase II Dysphagia trial by Icahn School of Medicine at Mount Sinai. Stop reason: OTHER/UNKNOWN.
Change in Investigational Drug Service policies resulting in the need to change the operational design of the overall protocol.
Phase IV External Cephalic Version trial by Icahn School of Medicine at Mount Sinai. Stop reason: EFFICACY/FUTILITY.
Interim analysis to assess concern for spinal anesthesia and increased cesarean delivery rate.
Phase II Ovarian Neoplasms trial by Icahn School of Medicine at Mount Sinai. Stop reason: OTHER/UNKNOWN.
Evolving data with Ipatasertib that changes the known risk / benefit background in pursuing future studies.
Phase IV Lung Cancer trial by Icahn School of Medicine at Mount Sinai. Stop reason: OPERATIONAL.
PI left institution and unable to find new PI
Phase I Asthma trial by Icahn School of Medicine at Mount Sinai. Stop reason: OTHER/UNKNOWN.
No stop-reason text available in the compact dataset.
Phase IV Obesity trial by Icahn School of Medicine at Mount Sinai. Stop reason: OPERATIONAL.
Lack of Enrollment
Unknown Ventricular Tachycardia trial by Icahn School of Medicine at Mount Sinai. Stop reason: OPERATIONAL.
could not meet enrollment goal
Phase IV Postoperative Delirium trial by Icahn School of Medicine at Mount Sinai. Stop reason: OTHER/UNKNOWN.
Pilot study initiated to provide support data for main grant GCO 06-0217 funded. only baseline characteristic data collected. no results for this study.
Phase III Pathological Gambling trial by Icahn School of Medicine at Mount Sinai. Stop reason: OPERATIONAL.
low enrollment
Phase IV Crohn's Disease trial by Icahn School of Medicine at Mount Sinai. Stop reason: OPERATIONAL.
Difficult recruitment
Phase I Urinary Bladder Neoplasms trial by Icahn School of Medicine at Mount Sinai. Stop reason: OPERATIONAL.
low accrual
Phase II Neuropathic Back Pain trial by Icahn School of Medicine at Mount Sinai. Stop reason: OPERATIONAL.
funding not available to continue
Phase II Heart Failure trial by Icahn School of Medicine at Mount Sinai. Stop reason: OPERATIONAL.
The enrollment has been terminated by the NHLBI for administrative reasons.
Phase II Polyp of Nasal Sinus trial by Icahn School of Medicine at Mount Sinai. Stop reason: OTHER/UNKNOWN.
A high percentage of patients were dropping out of the study and were not able to complete the protocol.
Phase II Melanoma trial by Icahn School of Medicine at Mount Sinai. Stop reason: EFFICACY/FUTILITY.
Primary Endpoint not met
Phase II Cutaneous Squamous Cell Carcinoma trial by Icahn School of Medicine at Mount Sinai. Stop reason: EFFICACY/FUTILITY.
Closed by sponsor
Phase IV Bipolar Disorder trial by Icahn School of Medicine at Mount Sinai. Stop reason: OTHER/UNKNOWN.
Change in available resources for study procedures
Phase II Prostate Cancer trial by Icahn School of Medicine at Mount Sinai. Stop reason: OPERATIONAL.
poor accrual
Unknown Pelvic Organ Prolapse trial by Icahn School of Medicine at Mount Sinai. Stop reason: OTHER/UNKNOWN.
No stop-reason text available in the compact dataset.
Unknown Fibromyalgia trial by Icahn School of Medicine at Mount Sinai. Stop reason: REGULATORY.
Due to FDA comments, changes required unavailable resources. There are no results for this study.
Unknown Major Depressive Disorder trial by Icahn School of Medicine at Mount Sinai. Stop reason: OTHER/UNKNOWN.
Change in resources available for study procedures.
Phase IV Body Dysmorphic Disorder trial by Icahn School of Medicine at Mount Sinai. Stop reason: OPERATIONAL.
low enrollment
Phase IV Schizotypal Personality Disorder trial by Icahn School of Medicine at Mount Sinai. Stop reason: OPERATIONAL.
low enrollment
Phase II Fatigue trial by Icahn School of Medicine at Mount Sinai. Stop reason: OPERATIONAL.
Insufficient recruitment