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Children's Hospital Medical Center, Cincinnati clinical trial failures
Review 34 stopped clinical trials from Children's Hospital Medical Center, Cincinnati, including disease areas, phases, and classified stop reasons.
This page groups real ClinicalTrials.gov-derived stopped trial records. The strongest added signal is the stop-reason classification: 2 of these records are likely biological failure signals, while the rest may reflect operational, strategic, regulatory, funding, enrollment, or unclear stop reasons.
Dominant stop reasons
- OPERATIONAL
- 18
- OTHER/UNKNOWN
- 14
- EFFICACY/FUTILITY
- 1
- SAFETY
- 1
Notable sponsors
- Children's Hospital Medical Center, Cincinnati
- 34
Related phases
- Phase II
- 13
- Phase I
- 8
- Early Phase I
- 4
- Phase III
- 4
- Phase IV
- 3
Crawlable stopped-trial records
Open ExploreShowing up to 34 representative records from this slice. Each link opens the trial detail page with source attribution and stop-reason context.
Phase II Hematopoietic Stem Cell Transplant (HSCT) trial by Children's Hospital Medical Center, Cincinnati. Stop reason: OPERATIONAL.
Study closed due to slow enrollment.
Phase II Crohn Disease trial by Children's Hospital Medical Center, Cincinnati. Stop reason: OTHER/UNKNOWN.
This was the Pilot study. The larger, confirmatory study has started
Phase I Chronic Graft Versus Host Disease trial by Children's Hospital Medical Center, Cincinnati. Stop reason: OPERATIONAL.
Study closed due to slow enrollment.
Early Phase I Ototoxicity, Drug-Induced trial by Children's Hospital Medical Center, Cincinnati. Stop reason: OTHER/UNKNOWN.
This study will be closing at CCHMC and may be transferred to a principal investigator at another insitutiton.
Phase II Neurofibromatosis 2 trial by Children's Hospital Medical Center, Cincinnati. Stop reason: OTHER/UNKNOWN.
Results review of patient data
Phase II Allogeneic Hematopoietic Cell Transplantation trial by Children's Hospital Medical Center, Cincinnati. Stop reason: OPERATIONAL.
Post-transplant cyclophosphamide and abatacept can be used as standard-of-care approaches to GVHD prevention in the HLA mismatched donor-recipient setting and are simpler to use since study enrollment is not required.
Phase II Lupus Nephritis trial by Children's Hospital Medical Center, Cincinnati. Stop reason: OPERATIONAL.
funding not secured
Phase II Allogeneic Hematopoietic Cell Transplantation trial by Children's Hospital Medical Center, Cincinnati. Stop reason: OTHER/UNKNOWN.
A new multisite study was opened in place of this study.
Unknown Minimally Invasive Fetoscopic Procedures trial by Children's Hospital Medical Center, Cincinnati. Stop reason: OTHER/UNKNOWN.
Deferred by IRB.
Phase II Tonsillectomy trial by Children's Hospital Medical Center, Cincinnati. Stop reason: OPERATIONAL.
Mentor for PI left institution. Study was not renewed.
Phase II Solid Tumors trial by Children's Hospital Medical Center, Cincinnati. Stop reason: OPERATIONAL.
The study was terminated as recommended by the DSMB due to inability to meet enrollment goals within the time frame allotted (target of 25 patients over 5 years).
Phase IV Choanal Atresia trial by Children's Hospital Medical Center, Cincinnati. Stop reason: OPERATIONAL.
Study terminated due to lack of funding.
Phase I Leukemia, B-cell trial by Children's Hospital Medical Center, Cincinnati. Stop reason: OPERATIONAL.
Lack of enrollment due to the availability of other novel salvage therapies for relapsed/refractory B-ALL.
Phase II Viral Infection trial by Children's Hospital Medical Center, Cincinnati. Stop reason: OPERATIONAL.
The use of steroids to treat COVID prevents the use of VSTs for these patients. The Principal Investigator does not feel the study had an expectation of enrolling patients as the treatment options for COVID have evolved.
Phase I High Grade Glioma trial by Children's Hospital Medical Center, Cincinnati. Stop reason: OTHER/UNKNOWN.
A competing trial was opened for patient population with combination of ribociclib and everolimus.
Phase IV Hematologic Diseases trial by Children's Hospital Medical Center, Cincinnati. Stop reason: OPERATIONAL.
Poor accrual
Phase I Magnetic Resonance Imaging trial by Children's Hospital Medical Center, Cincinnati. Stop reason: OPERATIONAL.
low enrollment and high participant withdraw
Early Phase I Pain trial by Children's Hospital Medical Center, Cincinnati. Stop reason: OPERATIONAL.
Study ended due to lack of funding.
Early Phase I Relapsed Lymphoblastic Leukemia trial by Children's Hospital Medical Center, Cincinnati. Stop reason: OPERATIONAL.
Slow Accrual
Early Phase I Retinoblastoma trial by Children's Hospital Medical Center, Cincinnati. Stop reason: OTHER/UNKNOWN.
Competing studies
Phase III Asthma trial by Children's Hospital Medical Center, Cincinnati. Stop reason: OPERATIONAL.
lack of funding
Phase IV Extreme Immaturity trial by Children's Hospital Medical Center, Cincinnati. Stop reason: OTHER/UNKNOWN.
The unit's standard nutrition practices change which impacted our methodology.
Phase II Congenital Heart Disease trial by Children's Hospital Medical Center, Cincinnati. Stop reason: OPERATIONAL.
Study was stopped early due to inability to recruit additional participants
Phase III Sickle Cell Anemia trial by Children's Hospital Medical Center, Cincinnati. Stop reason: EFFICACY/FUTILITY.
The study was stopped early due to successfully meeting the primary endpoint
Phase I Diagnoses That Require Stem Cell Transplant trial by Children's Hospital Medical Center, Cincinnati. Stop reason: OPERATIONAL.
slow recruitment and no further drug supply
Phase I Colorectal Surgery trial by Children's Hospital Medical Center, Cincinnati. Stop reason: OTHER/UNKNOWN.
Lack of available study participants.
Phase II Acute Kidney Injury trial by Children's Hospital Medical Center, Cincinnati. Stop reason: OTHER/UNKNOWN.
revised and combined with another protocol
Phase II Waning Donor Chimerism trial by Children's Hospital Medical Center, Cincinnati. Stop reason: OTHER/UNKNOWN.
CliniMACS CD34 Reagent System was FDA approved for clinical use; therefore, patients were treated clinically.
Phase I Immunocompromised trial by Children's Hospital Medical Center, Cincinnati. Stop reason: OTHER/UNKNOWN.
No stop-reason text available in the compact dataset.
Phase III Migraine trial by Children's Hospital Medical Center, Cincinnati. Stop reason: OTHER/UNKNOWN.
Interim assessment provided sufficient data to answer study questions
Unknown Retinoblastoma trial by Children's Hospital Medical Center, Cincinnati. Stop reason: OPERATIONAL.
No enrollment and competing studies
Phase II Ulcerative Colitis trial by Children's Hospital Medical Center, Cincinnati. Stop reason: SAFETY.
IND for this study remained on clinical hold
Phase I Colorectal Disorders trial by Children's Hospital Medical Center, Cincinnati. Stop reason: OTHER/UNKNOWN.
Study was closed due to recommendations of performing a PK study first.
Phase III Sickle Cell Anemia trial by Children's Hospital Medical Center, Cincinnati. Stop reason: OPERATIONAL.
inability to reach a satisfactory endpoint with respect to adequate recruitment