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Brown University clinical trial failures
Review 26 stopped clinical trials from Brown University, including disease areas, phases, and classified stop reasons.
This page groups real ClinicalTrials.gov-derived stopped trial records. The strongest added signal is the stop-reason classification: 4 of these records are likely biological failure signals, while the rest may reflect operational, strategic, regulatory, funding, enrollment, or unclear stop reasons.
Dominant stop reasons
- OPERATIONAL
- 17
- OTHER/UNKNOWN
- 5
- EFFICACY/FUTILITY
- 4
Notable sponsors
- Brown University
- 26
Related phases
- Phase II
- 16
- Phase I
- 10
Crawlable stopped-trial records
Open ExploreShowing up to 26 representative records from this slice. Each link opens the trial detail page with source attribution and stop-reason context.
Phase I Urothelial Carcinoma Bladder trial by Brown University. Stop reason: OPERATIONAL.
Principal Investigator left institution
Phase I Metastatic Melanoma trial by Brown University. Stop reason: OPERATIONAL.
Contract Issues
Phase II Prostate Cancer trial by Brown University. Stop reason: OPERATIONAL.
Lack of enrollment secondary to eligibility criteria
Phase II Cervical Cancer trial by Brown University. Stop reason: OPERATIONAL.
Slow enrollment
Phase II Rheumatoid Arthritis trial by Brown University. Stop reason: OPERATIONAL.
Termination of study funding
Phase I Advanced Breast Cancer trial by Brown University. Stop reason: OPERATIONAL.
Lack of accrual
Phase I Renal Cell Carcinoma Metastatic trial by Brown University. Stop reason: OPERATIONAL.
Funding withdrawn
Phase I BRCA1 Mutation trial by Brown University. Stop reason: OTHER/UNKNOWN.
termination of research grant agreement
Phase I Metastatic Colorectal Cancer trial by Brown University. Stop reason: EFFICACY/FUTILITY.
Lack of efficacy
Phase I Glioblastoma Multiforme trial by Brown University. Stop reason: EFFICACY/FUTILITY.
lack of response to study therapy
Phase II Tobacco Dependence trial by Brown University. Stop reason: OPERATIONAL.
Low rate of enrollment
Phase I Metastatic Pancreatic Cancer trial by Brown University. Stop reason: OPERATIONAL.
slow enrollment and lack of funding
Phase II Mantle Cell Lymphoma trial by Brown University. Stop reason: OPERATIONAL.
Lack of accrual and low efficacy
Phase II Prostate Cancer trial by Brown University. Stop reason: OPERATIONAL.
slow recruitment and lost funding
Phase II Melanoma trial by Brown University. Stop reason: OPERATIONAL.
Study stopped 10/24/13 secondary to lack of patients/slow enrollment
Phase I Prostate Cancer trial by Brown University. Stop reason: OTHER/UNKNOWN.
Lack of patients
Phase II Myelodysplasia trial by Brown University. Stop reason: EFFICACY/FUTILITY.
Lack of efficacy
Phase II Soft Tissue Sarcoma trial by Brown University. Stop reason: OTHER/UNKNOWN.
IND withdrawn
Phase II Sarcoma trial by Brown University. Stop reason: OTHER/UNKNOWN.
IND withdrawn
Phase II Diffuse Large B Cell Lymphoma trial by Brown University. Stop reason: OPERATIONAL.
lack of funding
Phase I Anal Cancer trial by Brown University. Stop reason: OTHER/UNKNOWN.
pilot data to be used for upcoming larger trial.
Phase II Metastatic Colorectal Cancer trial by Brown University. Stop reason: OPERATIONAL.
Lack of efficacy and enrollment
Phase II Colorectal Cancer trial by Brown University. Stop reason: EFFICACY/FUTILITY.
possible lack of efficacy
Phase II Breast Cancer trial by Brown University. Stop reason: OPERATIONAL.
DSMB determined toxicity of regimen more than originally thought. Slow accrual.
Phase II Invasive Bladder Cancer trial by Brown University. Stop reason: OPERATIONAL.
The study is being closed to accrual secondary to low accrual and an interest in opening up a different trial.
Phase II Lymphoma, Non-Hodgkins trial by Brown University. Stop reason: OPERATIONAL.
lack of accrual