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Baylor College of Medicine clinical trial failures
Review 72 stopped clinical trials from Baylor College of Medicine, including disease areas, phases, and classified stop reasons.
This page groups real ClinicalTrials.gov-derived stopped trial records. The strongest added signal is the stop-reason classification: 1 of these records are likely biological failure signals, while the rest may reflect operational, strategic, regulatory, funding, enrollment, or unclear stop reasons.
Dominant stop reasons
- OPERATIONAL
- 41
- OTHER/UNKNOWN
- 30
- SAFETY
- 1
Notable sponsors
- Baylor College of Medicine
- 72
Related phases
- Phase I
- 20
- Phase II
- 19
- Phase IV
- 13
- Unknown
- 13
- Early Phase I
- 4
Crawlable stopped-trial records
Open ExploreShowing up to 72 representative records from this slice. Each link opens the trial detail page with source attribution and stop-reason context.
Phase II Gastric Adenocarcinoma trial by Baylor College of Medicine. Stop reason: OPERATIONAL.
Since activation, 3 subjects were enrolled but were ineligible for randomization to a treatment arm because of a positive diagnostic laparoscopy result. Given the repeat inability to enroll and randomize an eligible subject; accrual was halted.
Phase II Endometriosis trial by Baylor College of Medicine. Stop reason: OTHER/UNKNOWN.
Due to an ongoing national shortage of dronabinol, the study is being discontinued. Given the inability to ensure consistent medication availability, continuation of the study would compromise protocol integrity and participant safety.
Phase I Radiation Dermatitis trial by Baylor College of Medicine. Stop reason: OTHER/UNKNOWN.
PI is leaving institution and this protocol will not be further pursued at this institution.
Phase IV Supracondylar Humerus Fracture trial by Baylor College of Medicine. Stop reason: OPERATIONAL.
After reviewing our enrollment numbers and feasibility, we have decided to close the study due to low enrollment.
Early Phase I Graft-Versus-Host Disease(GVHD) trial by Baylor College of Medicine. Stop reason: OPERATIONAL.
There is no funding.
Phase I Hypermobile Ehlers-Danlos Syndrome trial by Baylor College of Medicine. Stop reason: OPERATIONAL.
Study team has decided to close the trial (NCT05405257) due problems with patient recruitment and enrollment efforts. To date, only one patient completed both arms.
Phase I Hodgkins Lymphoma trial by Baylor College of Medicine. Stop reason: OTHER/UNKNOWN.
Leadership determination
Early Phase I Hypogonadism, Male trial by Baylor College of Medicine. Stop reason: OTHER/UNKNOWN.
No longer wanting to enroll or start study.
Phase II Biliary Atresia trial by Baylor College of Medicine. Stop reason: OPERATIONAL.
Target enrollment was not reached because the medication, pentoxifylline, has a taste that is not well tolerated by infants. The study team decided to end the study before meeting the enrollment goal because of the medication taste.
Phase I Abdominal Pain trial by Baylor College of Medicine. Stop reason: OTHER/UNKNOWN.
This study was superseded by NCT03295747
Phase I Extranodal Natural Killer/T-Cell Lymphoma, Nasal Type trial by Baylor College of Medicine. Stop reason: OTHER/UNKNOWN.
Study was not activated
Phase IV Insomnia Chronic trial by Baylor College of Medicine. Stop reason: OPERATIONAL.
Received alternative sources of funding.
Phase I SARS-CoV 2 trial by Baylor College of Medicine. Stop reason: OPERATIONAL.
Due to trial's eligibility criteria and the low census of hospitalized COVID-19 patients meeting eligibility criteria, the Sponsor will be unable to enroll a meaningful number of patients in this single-center trial in a reasonable time frame.
Unknown Chronic Phantom Limb Pain trial by Baylor College of Medicine. Stop reason: OTHER/UNKNOWN.
No patients were enrolled in this study. The study onset was delayed due to problems with drug acquisition.
Phase I Non-hodgkin Lymphoma trial by Baylor College of Medicine. Stop reason: OTHER/UNKNOWN.
We decided to move on to another product and as a result will not be moving forward with this study.
Phase I Mesothelioma trial by Baylor College of Medicine. Stop reason: SAFETY.
Change in research plan.
Early Phase I Gulf War Syndrome trial by Baylor College of Medicine. Stop reason: OPERATIONAL.
Due to the COVID pandemic we could not enroll more than one subject before funding was ending.
Phase IV Supracondylar Fractures trial by Baylor College of Medicine. Stop reason: OPERATIONAL.
Enrollment was suspended due to the duration of the study and poor follow-up response by participants.
Phase II Eosinophilic Esophagitis trial by Baylor College of Medicine. Stop reason: OPERATIONAL.
Recruitment was below expectation
Phase II Neurogenic Bladder Dysfunction Nos trial by Baylor College of Medicine. Stop reason: OTHER/UNKNOWN.
Funds no longer available
Phase IV Hypothyroidism trial by Baylor College of Medicine. Stop reason: OTHER/UNKNOWN.
No stop-reason text available in the compact dataset.
Phase II Hemoglobin SC Disease trial by Baylor College of Medicine. Stop reason: OPERATIONAL.
low enrollment
Phase IV Diabetes Mellitus, Type 2 trial by Baylor College of Medicine. Stop reason: OPERATIONAL.
Inability to recruit adequate Sample Size who met the entry criteria
Phase I Bladder Cancer trial by Baylor College of Medicine. Stop reason: OPERATIONAL.
The sponsor of this study has terminated the study due to poor enrollment.
Phase II Recurrent Urinary Tract Infection trial by Baylor College of Medicine. Stop reason: OTHER/UNKNOWN.
Withdrawn by PI
Phase II Pulmonary Lymphangioleiomyomatosis trial by Baylor College of Medicine. Stop reason: OTHER/UNKNOWN.
No stop-reason text available in the compact dataset.
Unknown Asthma trial by Baylor College of Medicine. Stop reason: OTHER/UNKNOWN.
Different study was designed
Phase III Sickle Cell Disease trial by Baylor College of Medicine. Stop reason: OPERATIONAL.
poor enrollment, availability of more effective medications
Phase IV Pectus Excavatum trial by Baylor College of Medicine. Stop reason: OTHER/UNKNOWN.
New method of pain control pushed by surgeons.
Phase I Hepatocellular Carcinoma trial by Baylor College of Medicine. Stop reason: OTHER/UNKNOWN.
The key elements of this study were incorporated into another study.
Unknown Thalassemia trial by Baylor College of Medicine. Stop reason: OTHER/UNKNOWN.
Stem cell transplant was determined SOC for this disease (study is not relevant)
Phase IV Type 2 Diabetes Mellitus trial by Baylor College of Medicine. Stop reason: OPERATIONAL.
Due to difficulty with enrollment of subjects
Phase IV End-stage Liver Disease trial by Baylor College of Medicine. Stop reason: OPERATIONAL.
insufficient funding
Unknown Dysphagia trial by Baylor College of Medicine. Stop reason: OPERATIONAL.
no subject met enrollment criteria
Unknown Dry Eye trial by Baylor College of Medicine. Stop reason: OPERATIONAL.
Funding was terminated
Phase II Hemoglobin SC Disease trial by Baylor College of Medicine. Stop reason: OPERATIONAL.
Insufficient accrual
Phase II Sickle Cell Anemia trial by Baylor College of Medicine. Stop reason: OTHER/UNKNOWN.
unable to accrue patients
Phase I Graft Failure trial by Baylor College of Medicine. Stop reason: OPERATIONAL.
accrual was slow
Phase II Sickle Cell Anemia trial by Baylor College of Medicine. Stop reason: OPERATIONAL.
accrual was slow and sporadic so the study was closed
Phase IV Impaired Glucose Tolerance trial by Baylor College of Medicine. Stop reason: OPERATIONAL.
difficulty with enrollment of subjects
Phase III ERYTHROCYTOSIS trial by Baylor College of Medicine. Stop reason: OPERATIONAL.
Funding was not available.
Phase IV Atherosclerosis trial by Baylor College of Medicine. Stop reason: OPERATIONAL.
Pharmaceutical company sponsor withdrew support prior to enrollment of subjects.
Phase II Cocaine Dependence trial by Baylor College of Medicine. Stop reason: OTHER/UNKNOWN.
Results of interim efficacy analysis showed results were not promising.
Phase II Infertility trial by Baylor College of Medicine. Stop reason: OPERATIONAL.
Difficult eligibility and lack of funding
Phase IV Cleft Palate trial by Baylor College of Medicine. Stop reason: OPERATIONAL.
Recruitment concerns
Phase III Placenta Accreta trial by Baylor College of Medicine. Stop reason: OTHER/UNKNOWN.
More preparation needed prior to collecting data.
Phase I Fanconi Anemia trial by Baylor College of Medicine. Stop reason: OPERATIONAL.
slow accrual
Phase I Neuroblastoma trial by Baylor College of Medicine. Stop reason: OTHER/UNKNOWN.
Based on newly available preclinical data we changed the CAR construct to a more effective version and will now study that product on a different protocol.
Unknown Urinary Tract Infection trial by Baylor College of Medicine. Stop reason: OPERATIONAL.
Study catheter manufacturing issues. Poor enrollment.
Phase IV IgA Nephropathy trial by Baylor College of Medicine. Stop reason: OPERATIONAL.
There were no subjects enrolled locally on this study since it opened. Local IRB closure has been requested.
Phase I Lymphoma trial by Baylor College of Medicine. Stop reason: OTHER/UNKNOWN.
No stop-reason text available in the compact dataset.
Unknown Analgesia trial by Baylor College of Medicine. Stop reason: OPERATIONAL.
Unable to enroll. Change in patient population.
Phase II Preeclampsia trial by Baylor College of Medicine. Stop reason: OPERATIONAL.
Lack of funding
Phase II Traumatic Brain Injury trial by Baylor College of Medicine. Stop reason: OPERATIONAL.
inability to recruit adequate numbers of subjects
Phase I Hematologic Malignancies trial by Baylor College of Medicine. Stop reason: OPERATIONAL.
Slow accrual due to practice changes meant study would take too long to finish
Phase IV Clostridium Difficile trial by Baylor College of Medicine. Stop reason: OPERATIONAL.
Lost funding due to low enrollment.
Phase II Sturge Weber Syndrome trial by Baylor College of Medicine. Stop reason: OTHER/UNKNOWN.
Site did not want to pursue study
Phase I Myelodysplastic and Myeloproliferative Disorders trial by Baylor College of Medicine. Stop reason: OPERATIONAL.
slow accrual
Unknown Leukemia trial by Baylor College of Medicine. Stop reason: OTHER/UNKNOWN.
No stop-reason text available in the compact dataset.
Unknown Leukemia trial by Baylor College of Medicine. Stop reason: OTHER/UNKNOWN.
No stop-reason text available in the compact dataset.
Phase II Aplastic Anemia trial by Baylor College of Medicine. Stop reason: OTHER/UNKNOWN.
No stop-reason text available in the compact dataset.
Unknown Pain, Postoperative trial by Baylor College of Medicine. Stop reason: OTHER/UNKNOWN.
Shortages of study drug, difficulty enrolling patients
Phase I B-cell Chronic Lymphocytic Leukemia trial by Baylor College of Medicine. Stop reason: OTHER/UNKNOWN.
No stop-reason text available in the compact dataset.
Unknown Parkinson's Disease trial by Baylor College of Medicine. Stop reason: OPERATIONAL.
PI left site
Phase I Cardiac Transplantation trial by Baylor College of Medicine. Stop reason: OPERATIONAL.
Slow enrollment
Phase II Pain trial by Baylor College of Medicine. Stop reason: OTHER/UNKNOWN.
Withdrawn by PI
Phase I Inherited Metabolic Storage Diseases trial by Baylor College of Medicine. Stop reason: OTHER/UNKNOWN.
No stop-reason text available in the compact dataset.
Phase II Malignant Ascites trial by Baylor College of Medicine. Stop reason: OPERATIONAL.
Accrual closed by sponsor due to lack of accrual and study progress
Phase I Erectile Dysfunction trial by Baylor College of Medicine. Stop reason: OPERATIONAL.
Contract issues
Unknown Subarachnoid Hemorrhage trial by Baylor College of Medicine. Stop reason: OTHER/UNKNOWN.
Study met safety endpoints
Early Phase I Tourniquet-induced Pain trial by Baylor College of Medicine. Stop reason: OPERATIONAL.
Unable to recruit patient due to surgical case type. Not worth continuing study.
Unknown Pain, Sciatic Block trial by Baylor College of Medicine. Stop reason: OPERATIONAL.
Inability to recruit subjects at our hospital due to change in surgical patient population. Not worth to continue.