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Assistance Publique - Hôpitaux de Paris clinical trial failures
Review 74 stopped clinical trials from Assistance Publique - Hôpitaux de Paris, including disease areas, phases, and classified stop reasons.
This page groups real ClinicalTrials.gov-derived stopped trial records. The strongest added signal is the stop-reason classification: 8 of these records are likely biological failure signals, while the rest may reflect operational, strategic, regulatory, funding, enrollment, or unclear stop reasons.
Dominant stop reasons
- OTHER/UNKNOWN
- 40
- OPERATIONAL
- 26
- SAFETY
- 5
- EFFICACY/FUTILITY
- 3
Notable sponsors
- Assistance Publique - Hôpitaux de Paris
- 74
Related phases
- Phase III
- 27
- Phase II
- 26
- Phase IV
- 11
- Unknown
- 7
- Phase I
- 3
Crawlable stopped-trial records
Open ExploreShowing up to 74 representative records from this slice. Each link opens the trial detail page with source attribution and stop-reason context.
Phase II Hepatocellular Carcinoma trial by Assistance Publique - Hôpitaux de Paris. Stop reason: OPERATIONAL.
Because patient recruitment was affected by the COVID-19 pandemic, the study sponsor and funding partner halted enrollment at that time to meet contractual obligations
Phase II Antiphospholipid Syndrome in Pregnancy trial by Assistance Publique - Hôpitaux de Paris. Stop reason: OTHER/UNKNOWN.
The study was terminated following revisions to the diagnostic criteria defining the target pathology, which significantly impacted the study design
Phase II MSI trial by Assistance Publique - Hôpitaux de Paris. Stop reason: OTHER/UNKNOWN.
The study has been halted because the manufacturer can no longer supply the experimental treatment
Phase IV Small for Gestational Age trial by Assistance Publique - Hôpitaux de Paris. Stop reason: OTHER/UNKNOWN.
no more inclusions
Unknown Spondyloarthritis trial by Assistance Publique - Hôpitaux de Paris. Stop reason: OPERATIONAL.
The study of the long term antibody response is no longer relative due to the introduction of Covid vaccine.
Phase II Combined Immunodeficiencies trial by Assistance Publique - Hôpitaux de Paris. Stop reason: OTHER/UNKNOWN.
No stop-reason text available in the compact dataset.
Phase IV Hemorrhage trial by Assistance Publique - Hôpitaux de Paris. Stop reason: EFFICACY/FUTILITY.
reason of halt prematurely: futility of the trial
Unknown Severe/Moderate Coronavirus trial by Assistance Publique - Hôpitaux de Paris. Stop reason: OTHER/UNKNOWN.
Abandonment of the study project
Phase IV Positive Helicobacter Pylori Serology trial by Assistance Publique - Hôpitaux de Paris. Stop reason: OTHER/UNKNOWN.
no inclusion
Unknown Paraphilia trial by Assistance Publique - Hôpitaux de Paris. Stop reason: OTHER/UNKNOWN.
Change of sponsor
Phase II Gout trial by Assistance Publique - Hôpitaux de Paris. Stop reason: OPERATIONAL.
Peremption of treatments, difficulty of patients recrutment (28 patients in 3 years) and lack of funding to pursue the study.
Phase II Out-of-hospital Cardiac Arrest (OHCA) trial by Assistance Publique - Hôpitaux de Paris. Stop reason: OTHER/UNKNOWN.
As the inclusion period in the study has ended and regulatory authorizations have expired on 26/12/2023, with no inclusions conducted.
Unknown Duchenne Muscular Dystrophy trial by Assistance Publique - Hôpitaux de Paris. Stop reason: OTHER/UNKNOWN.
Cancellation of financing by the financier.
Phase I Subclinical Acute Antibody-mediated Rejection in Kidney Transplantation trial by Assistance Publique - Hôpitaux de Paris. Stop reason: OTHER/UNKNOWN.
disengagement of the sponsor Alexion Pharmaceuticals
Phase III Stem Cell Transplant Complications trial by Assistance Publique - Hôpitaux de Paris. Stop reason: OPERATIONAL.
insufficient enrollment.
Phase III Migraine trial by Assistance Publique - Hôpitaux de Paris. Stop reason: OPERATIONAL.
It has been determined that continuing with enrollments in this study is no longer justified due to the lack of significant impact on the expected outcomes.
Phase III Gestational Diabetes Mellitus in Pregnancy trial by Assistance Publique - Hôpitaux de Paris. Stop reason: OPERATIONAL.
difficulty in recruiting
Phase IV Gout Flare trial by Assistance Publique - Hôpitaux de Paris. Stop reason: OTHER/UNKNOWN.
faillure of recrutement
Phase III Emergence Delirium trial by Assistance Publique - Hôpitaux de Paris. Stop reason: OPERATIONAL.
Sponsor decision:
Unknown Quaternary Ammonium trial by Assistance Publique - Hôpitaux de Paris. Stop reason: OTHER/UNKNOWN.
there is not enough volounteer for the trial
Phase III Severe Trauma Patients trial by Assistance Publique - Hôpitaux de Paris. Stop reason: EFFICACY/FUTILITY.
Premature termination due to futility following interim analysis
Phase III Epilepticus trial by Assistance Publique - Hôpitaux de Paris. Stop reason: OTHER/UNKNOWN.
Lack of inclusion
Phase IV Rheumatoid Arthritis trial by Assistance Publique - Hôpitaux de Paris. Stop reason: OTHER/UNKNOWN.
Difficulties of inclusion in the study following expiry of the experimental treatment. The time required to supply the study treatment is too long to obtain conclusive results at the end of the study.
Phase II Crohn Disease trial by Assistance Publique - Hôpitaux de Paris. Stop reason: OPERATIONAL.
insufficient recruitment
Phase II Oesophageal Adenocarcinoma trial by Assistance Publique - Hôpitaux de Paris. Stop reason: SAFETY.
Sponsor decision up DSMB advice due to unfavorable toxicity profile
Phase III Venous Thromboembolism trial by Assistance Publique - Hôpitaux de Paris. Stop reason: OTHER/UNKNOWN.
The rate of inclusion is too low to hope to reach the target of 800 patients. 59 patients were included, and their data will not meet the research objectives. The sponsor has decided to prematurely stop inclusions on January 13, 2022.
Phase II Advanced Head and Neck Carcinoma trial by Assistance Publique - Hôpitaux de Paris. Stop reason: OTHER/UNKNOWN.
Change in protocol strategy
Phase III Coronary Arteriosclerosis trial by Assistance Publique - Hôpitaux de Paris. Stop reason: OPERATIONAL.
Financial issues
Phase III Colon Cancer trial by Assistance Publique - Hôpitaux de Paris. Stop reason: OTHER/UNKNOWN.
lack of inclusions
Phase III Attention Deficit Hyperactivity Disorder (ADHD) trial by Assistance Publique - Hôpitaux de Paris. Stop reason: OTHER/UNKNOWN.
insufficient recrutement in the study
Phase III Osteoid Osteoma trial by Assistance Publique - Hôpitaux de Paris. Stop reason: OPERATIONAL.
The study has been conducted until the end of the research; participants are no longer receiving an intervention or being examined; but recruitment isn't completed (15 % enrolled in the stud)
Phase III Covid19 trial by Assistance Publique - Hôpitaux de Paris. Stop reason: OPERATIONAL.
Scientific committee decision due SARS-CoV2 pandemic evolution with a decrease in inclusions and widespread distribution of vaccines
Phase II Steroid-Dependent Nephrotic Syndrome trial by Assistance Publique - Hôpitaux de Paris. Stop reason: SAFETY.
Decision of Data Safety Monitoring Board
Phase III Covid-19 Infection trial by Assistance Publique - Hôpitaux de Paris. Stop reason: OPERATIONAL.
Insufficient recruitment
Phase II Cannabis Dependence trial by Assistance Publique - Hôpitaux de Paris. Stop reason: OPERATIONAL.
lack of recruitment
Phase III History of Cardiovascular Disease Treated With RAS Blockers and With SARS-CoV-2 Infection trial by Assistance Publique - Hôpitaux de Paris. Stop reason: OPERATIONAL.
insufficient recrutment
Phase III COVID-19 trial by Assistance Publique - Hôpitaux de Paris. Stop reason: OPERATIONAL.
Stop inclusions for insufficient recruitment
Phase IV Acute Kidney Injury trial by Assistance Publique - Hôpitaux de Paris. Stop reason: OTHER/UNKNOWN.
Study end date exceeded and insufficient number of subjects needed for analysis. 11 patients included / 70 theoretical patients
Phase III Brugada Syndrome trial by Assistance Publique - Hôpitaux de Paris. Stop reason: OPERATIONAL.
recruitments issues
Phase III Covid-19 trial by Assistance Publique - Hôpitaux de Paris. Stop reason: OTHER/UNKNOWN.
Regulatory approvals have not been obtained
Phase II Selenoprotein N-related Myopathy trial by Assistance Publique - Hôpitaux de Paris. Stop reason: OTHER/UNKNOWN.
No stop-reason text available in the compact dataset.
Phase II COVID19 trial by Assistance Publique - Hôpitaux de Paris. Stop reason: EFFICACY/FUTILITY.
DSMB recommendation (futility)
Phase II Multiple Myeloma trial by Assistance Publique - Hôpitaux de Paris. Stop reason: SAFETY.
Promotor decision
Phase III Pulmonary Arterial Hypertension trial by Assistance Publique - Hôpitaux de Paris. Stop reason: OPERATIONAL.
Sponsor's decision
Phase II Congenital Cytomegalovirus (CMV) trial by Assistance Publique - Hôpitaux de Paris. Stop reason: OTHER/UNKNOWN.
No eligibles patients
Phase II Immune Thrombocytopenia trial by Assistance Publique - Hôpitaux de Paris. Stop reason: OTHER/UNKNOWN.
Decision of sponsor: impossibility of contract with Takeda
Phase III Locally Advanced Pancreatic Cancer trial by Assistance Publique - Hôpitaux de Paris. Stop reason: OPERATIONAL.
recruitment problem
Phase II Multiple Myeloma trial by Assistance Publique - Hôpitaux de Paris. Stop reason: OPERATIONAL.
Investigator decision in accordance with the promotor
Phase II Thyroid Cancer trial by Assistance Publique - Hôpitaux de Paris. Stop reason: OTHER/UNKNOWN.
inefficiency
Phase II Cryoglobulinemia trial by Assistance Publique - Hôpitaux de Paris. Stop reason: OPERATIONAL.
lack of recruitment
Phase III Ventilator-associated Pneumonia trial by Assistance Publique - Hôpitaux de Paris. Stop reason: OTHER/UNKNOWN.
Lack of inclusion
Phase I Renal Insufficiency, Chronic trial by Assistance Publique - Hôpitaux de Paris. Stop reason: SAFETY.
The study was suspended after a suspected unexpected serious adverse event.
Phase III Prader-Willi Syndrome trial by Assistance Publique - Hôpitaux de Paris. Stop reason: OTHER/UNKNOWN.
No stop-reason text available in the compact dataset.
Phase II Premature Birth trial by Assistance Publique - Hôpitaux de Paris. Stop reason: OTHER/UNKNOWN.
No stop-reason text available in the compact dataset.
Phase III Cirrhosis trial by Assistance Publique - Hôpitaux de Paris. Stop reason: OTHER/UNKNOWN.
Premature discontinuation of inclusions by the sponsor for low inclusion
Phase IV Hypertension trial by Assistance Publique - Hôpitaux de Paris. Stop reason: OTHER/UNKNOWN.
No stop-reason text available in the compact dataset.
Unknown Acute Pyelonephritis Without Severity Symptoms Due to ESBL-producing E.Coli trial by Assistance Publique - Hôpitaux de Paris. Stop reason: OTHER/UNKNOWN.
Not enought inclusion
Phase III Otosclerosis trial by Assistance Publique - Hôpitaux de Paris. Stop reason: OTHER/UNKNOWN.
lack of inclusion
Phase II Children trial by Assistance Publique - Hôpitaux de Paris. Stop reason: SAFETY.
Removal of Adrénaline lots for safety reasons.
Phase I Coronary Disease trial by Assistance Publique - Hôpitaux de Paris. Stop reason: OTHER/UNKNOWN.
Contamination of the Pitié-Salpêtrière biotherapy laboratory
Phase IV Urinary Infection trial by Assistance Publique - Hôpitaux de Paris. Stop reason: OPERATIONAL.
The study was stopped for recruitment defect
Phase IV Plantar Warts trial by Assistance Publique - Hôpitaux de Paris. Stop reason: OPERATIONAL.
Difficulty to enrollment patients
Phase III Hepatocellular Carcinoma trial by Assistance Publique - Hôpitaux de Paris. Stop reason: OTHER/UNKNOWN.
Decision of investigator
Phase II Dermatofibrosarcomas of DARIER FERRAND(DFSP) trial by Assistance Publique - Hôpitaux de Paris. Stop reason: OTHER/UNKNOWN.
Decision of Study Principal Investigator
Phase IV Depression trial by Assistance Publique - Hôpitaux de Paris. Stop reason: OTHER/UNKNOWN.
Investigator's decision
Unknown Renal Sarcoidosis trial by Assistance Publique - Hôpitaux de Paris. Stop reason: OPERATIONAL.
insufficient recruitment
Phase III Cirrhosis trial by Assistance Publique - Hôpitaux de Paris. Stop reason: OPERATIONAL.
lack of recruitement
Phase III Marfan Syndrome trial by Assistance Publique - Hôpitaux de Paris. Stop reason: OTHER/UNKNOWN.
A similar publication has been released, suggesting a beneficial effect of sartans, and only 15 patients remained to be seen for their visit at 36 months.
Phase III Heart-lung Transplant Rejection trial by Assistance Publique - Hôpitaux de Paris. Stop reason: OTHER/UNKNOWN.
No stop-reason text available in the compact dataset.
Phase II Neuroendocrine Tumors trial by Assistance Publique - Hôpitaux de Paris. Stop reason: OPERATIONAL.
lack of recruitement
Phase II Canavan Disease trial by Assistance Publique - Hôpitaux de Paris. Stop reason: OTHER/UNKNOWN.
No stop-reason text available in the compact dataset.
Phase IV Metastatic Renal Cell Carcinoma trial by Assistance Publique - Hôpitaux de Paris. Stop reason: OTHER/UNKNOWN.
No stop-reason text available in the compact dataset.
Phase II Brain Injury trial by Assistance Publique - Hôpitaux de Paris. Stop reason: OPERATIONAL.
Sponsor decision
Phase II Cystic Fibrosis trial by Assistance Publique - Hôpitaux de Paris. Stop reason: OTHER/UNKNOWN.
No stop-reason text available in the compact dataset.