Automatically calculated report

Latest two-week stopped trial updates

This report covers records updated from 18 July 2026 through 31 July 2026. It recalculates from the newest available ingest whenever the site builds.

Updated stopped records127

Terminated, suspended, or withdrawn records in the window.

Biological signals8

6.3% classified as efficacy/futility or safety signals.

Window start2026-07-18

Thirteen days before the latest ingested update date.

Latest update2026-07-31

The newest registry update date available in this ingest.

Source-linked records

Notable efficacy and safety updates

These records are selected from the latest window because their stop language is classified as efficacy/futility or safety. Open the trial page before using any item in research or reporting.

NCT06881251EFFICACY/FUTILITY

A Study of JNJ-95475939 in the Treatment of Participants With Moderate to Severe Atopic Dermatitis (AD)

Sponsor
Janssen Research & Development, LLC
Phase
Phase II
Disease area
Dermatology
Updated
2026-07-31
Registry stop language

Terminated: futility criteria met at interim efficacy analysis.

Open source-linked trial detail →
NCT06217939EFFICACY/FUTILITY

Early Intravenous Hydrocortisone in Sepsis

Sponsor
Siriraj Hospital
Phase
Unknown
Disease area
Infectious Disease
Updated
2026-07-28
Registry stop language

The study was terminated early on December 25, 2025, following the Data and Safety Monitoring Board (DSMB) recommendation due to preliminary evidence of futility.

Open source-linked trial detail →
NCT03417739EFFICACY/FUTILITY

A Phase II Study of BVD-523 in Metastatic Uveal Melanoma

Sponsor
Dana-Farber Cancer Institute
Phase
Phase II
Disease area
Oncology
Updated
2026-07-27
Registry stop language

This was a Simon two stage design trial that terminated after the first stage due to lack of response.

Open source-linked trial detail →

Ketamine HCl Prolonged Release Oral Tablets for CRPS

Sponsor
University of Southern California
Phase
Phase II
Disease area
Other
Updated
2026-07-27
Registry stop language

Difficulty clearing through the FDA

Open source-linked trial detail →
NCT07025564EFFICACY/FUTILITY

MiRisten for the Treatment of Relapsed or Refractory Acute Myeloid Leukemia

Sponsor
City of Hope Medical Center
Phase
Phase I
Disease area
Oncology
Updated
2026-07-24
Registry stop language

Pending Interim Analysis

Open source-linked trial detail →

Study of Evorpacept (ALX148) With Cetuximab and Pembrolizumab for Refractory Microsatellite Stable Metastatic Colorectal Cancer

Sponsor
University of Colorado, Denver
Phase
Phase II
Disease area
Oncology
Updated
2026-07-22
Registry stop language

Accrual was terminated due to safety concerns

Open source-linked trial detail →
NCT05746559EFFICACY/FUTILITY

ARTEMIS: Ravulizumab to Protect Patients With CKD From CSA-AKI and MAKE

Sponsor
Alexion Pharmaceuticals, Inc.
Phase
Phase III
Disease area
Cardiovascular
Updated
2026-07-22
Registry stop language

The ALXN1210-CSA-AKI-318 trial was discontinued on 29-Apr-2026 due to lack of efficacy in this overall study universe / patient population.

Open source-linked trial detail →
NCT04569084EFFICACY/FUTILITY

Efficacy and Safety Study of Oral Edaravone Administered in Subjects With ALS

Sponsor
Shionogi
Phase
Phase III
Disease area
Neurology
Updated
2026-07-20
Registry stop language

Futility was met.

Open source-linked trial detail →

Status mix

TERMINATED
77
SUSPENDED
38
WITHDRAWN
12

Stop-reason mix

OPERATIONAL
67
OTHER/UNKNOWN
51
EFFICACY/FUTILITY
6
SAFETY
2
REGULATORY
1

Largest disease areas

Oncology
68
Other
20
Cardiovascular
8
Gastroenterology & Hepatology
8
Neurology
5
Immunology & Autoimmune
4

Largest sponsor counts

National Cancer Institute (NCI)
16
M.D. Anderson Cancer Center
11
Boehringer Ingelheim
3
National Institute of Allergy and Infectious Diseases (NIAID)
3
Shanghai Junshi Bioscience Co., Ltd.
3
Washington University School of Medicine
3

How to use this report

Use it as a monitoring and triage layer. Status alone does not establish drug failure, and short registry explanations can omit endpoint, safety, or strategic context. Verify important findings against ClinicalTrials.gov and related primary documents.