Explore terminated, suspended, and withdrawn clinical trials
Search the ClinicalTrials.gov-derived stopped-trial dataset by sponsor, phase, disease area, intervention, status, and classified stop reason.
23,452 results
Sel
Trial
Title
Phase
Disease area
Condition
Intervention
Status
Reason
Why stopped
Last updated
The Effect of Oxytocin Administration on Interpersonal Cooperation in Borderline Personality Disorder Patients and Healthy Adults
Icahn School of Medicine at Mount Sinai
Unknown
Other
Borderline Personality Disorder
40 IU Intranasal Oxytocin
SUSPENDED
OPERATIONAL
Study was halted during COVID pandemic. However, PI is currently reconnecting with a compounding pharmacy to re-establish supply of the oxytocin and updating cost estimates. We are hoping to resume the pilot work with oxytocin once it is clarified.
2026-07-02
A Safety and Antitumor Activity Trial of Immunoradiotherapy Combinations as a Treatment Option for Subjects With Metastatic Solid Tumors
Genmab
Phase I
Oncology
Non-CNS Tumor
GEN1042
TERMINATED
EFFICACY/FUTILITY
After reviewing all available data from Part 1 of the trial, the Sponsor has decided not to proceed to Part 2 (randomized Phase 2) of the trial due to lack of efficacy
2026-07-02
Safety Evaluation of PfSPZ Vaccine in Pregnant Women in Mali (MalVIP1)
National Institute of Allergy and Infectious Diseases (NIAID)
Phase I
Infectious Disease
Malaria
PfSPZ Vaccine
SUSPENDED
REGULATORY
The study remains on hold due to a funding issue after it's been lifted by the FDA.
2026-07-02
Study to Evaluate the Use of Triheptanoin in Patients With Medium Chain Acyl-CoA Dehydrogenase Deficiency (MCADD)
Jerry Vockley, MD, PhD
Phase II
Other
Medium-chain Acyl-CoA Dehydrogenase Deficiency
Triheptanoin
WITHDRAWN
OPERATIONAL
funding was pulled
2026-07-02
Perioperative Propranolol in Patients With Post Traumatic Stress Disorder (PTSD)
University of California, San Francisco
Phase IV
Other
Post-traumatic Stress Disorder
Propranolol Hydrochloride
TERMINATED
OPERATIONAL
Unable to meet enrollment goals
2026-07-02
A Study to Investigate the Safety and Efficacy of KER-012 in Combination With Background Therapy in Adult Participants With Pulmonary Arterial Hypertension (PAH) (TROPOS Study).
Keros Therapeutics, Inc.
Phase II
Cardiovascular
Pulmonary Arterial Hypertension
Dose A KER-012
TERMINATED
SAFETY
The study was voluntarily terminated early, following a safety review and observation of pericardial effusions.
2026-07-02
Safety and Efficacy of Hectorol in Pediatric Patients With Chronic Kidney Disease Stage 3 and 4 With Secondary Hyperparathyroidism Not Yet on Dialysis
Sanofi
Phase III
Endocrine & Metabolic
Secondary Hyperparathyroidism-Chronic Kidney Disease
Doxercalciferol (GZ427397)
TERMINATED
OPERATIONAL
The study was conducted to fulfill a post-marketing commitment (PMC).FDA acknowledged the fulfillment of this PMC.
2026-07-02
RemImazolam Besylate for ICU-sedation in Patients With Mechanical Ventilation After Oral and Maxillofacial Surgery
Nanfang Hospital, Southern Medical University
Phase IV
Other
Sedation
Remimazolam Besylate
TERMINATED
OPERATIONAL
The trial was terminated early because additional sites did not recruit as planned, making the multicenter sample size infeasible. Enrollment ended after 117 participants were randomized at Nanfang Hospital, unrelated to safety, efficacy, or outcomes
2026-07-02
Testing Low Dose Tamoxifen for Invasive Breast Cancer, LoTam Trial
Alliance for Clinical Trials in Oncology
Phase III
Oncology
Anatomic Stage 0 Breast Cancer AJCC v8
Anastrozole
SUSPENDED
OTHER/UNKNOWN
Amending protocol to increase sample size
2026-07-02
Nivolumab and Ipilimumab in Treating Patients With Esophageal and Gastroesophageal Junction Adenocarcinoma Undergoing Surgery
National Cancer Institute (NCI)
Phase II
Gastroenterology & Hepatology
Clinical Stage II Esophageal Adenocarcinoma AJCC v8
Biospecimen Collection
SUSPENDED
OTHER/UNKNOWN
End of Initial Phase of Multi-phase protocol
2026-07-02
Losartan and Hypofractionated Rx After Chemo for Tx of Borderline Resectable or Locally Advanced Pancreatic Cancer
University of Utah
Phase I
Oncology
Borderline Resectable Pancreatic Adenocarcinoma
Hypofractionated Radiation Therapy
TERMINATED
OPERATIONAL
Closed due to slow accrual
2026-07-02
Testing the Addition of Radiation Therapy to the Usual Treatment (Immunotherapy With or Without Chemotherapy) for Advanced Stage Non-small Cell Lung Cancer Patients Who Are PD-L1 Negative
National Cancer Institute (NCI)
Phase II
Oncology
Lung Adenocarcinoma
Biopsy Procedure
SUSPENDED
OTHER/UNKNOWN
End of Initial Phase of Multi-phase protocol
2026-07-02
Nivolumab Plus Relatlimab and Gemcitabine/Cisplatin as First-Line Treatment in Advanced Biliary Tract Cancer.
National Health Research Institutes, Taiwan
Phase II
Oncology
Advanced Biliary Tract Cancer(BTC)
Nivolumab
WITHDRAWN
OPERATIONAL
The study was terminated due to administrative reasons following the cancellation of collaboration between the involved parties.
2026-07-02
Evaluation of a Cancer Lysate Vaccine and Montanide (Registered Trademark) ISA-51 VG With or Without the IL-15 Super-Agonist N-803 as Adjuvant Therapy for PD-L1 Negative Non-Small Cell Lung Cancer
National Cancer Institute (NCI)
Phase I
Oncology
Non-Small Cell Lung Cancer
Montanide (Registered Trademark) ISA-51 VG Adjuvant
SUSPENDED
OPERATIONAL
Revisions to eligibility/design being made prior to enrollment of first participants.
2026-07-02
Subcutaneous Epcoritamab With or Without Lenalidomide as First Line Therapy for Diffuse Large B-Cell Lymphoma
Genmab
Phase II
Oncology
Diffuse Large B-Cell Lymphoma
Epcoritamab
TERMINATED
OTHER/UNKNOWN
The study was terminated because sufficient data had been collected to meet the objectives of the development program. No new or unexpected safety findings were identified, and the decision to terminate was not related to participant safety.
2026-07-02
Testing the Addition of an Immunotherapy Drug, Cemiplimab (REGN2810), Plus Surgery to the Usual Surgery Alone for Treating Advanced Skin Cancer
National Cancer Institute (NCI)
Phase III
Oncology
Eyelid Squamous Cell Carcinoma
Biospecimen Collection
SUSPENDED
OTHER/UNKNOWN
Other - Other
2026-07-02
Testing the Addition of Duvelisib or CC-486 to the Usual Treatment for Peripheral T-Cell Lymphoma
Alliance for Clinical Trials in Oncology
Phase II
Gastroenterology & Hepatology
Angioimmunoblastic T-cell Lymphoma
Cyclophosphamide
SUSPENDED
EFFICACY/FUTILITY
Interim Analysis
2026-07-02
A Phase 1/2, Open-label, Multicenter, Dose Escalation and Expansion Study of SLC-3010 Monotherapy and in Combination
Selecxine
Phase I
Oncology
Advanced Solid Tumor
SLC-3010
TERMINATED
OPERATIONAL
Business decision
2026-07-02
Combination Therapy (Mirdametinib and Sirolimus) for RAS Mutated Relapsed Refractory Multiple Myeloma
National Cancer Institute (NCI)
Phase I
Oncology
Multiple Myeloma
Mirdametinib
SUSPENDED
OPERATIONAL
Administrative hold pending non-safety related changes to the study design.
2026-07-02
Study of Triheptanoin for the Prevention of Hypoglycemia in Patients With Medium Chain Acyl-CoA Dehydrogenase Deficiency (MCADD)
Jerry Vockley, MD, PhD
Phase II
Other
Medium-chain Acyl-CoA Dehydrogenase Deficiency
Triheptanoin
WITHDRAWN
OPERATIONAL
Funding was pulled
2026-07-02
Studying the Biology of IDH-mutant Gliomas Via Longitudinal Observation of 2-hydroxyglutarate (2-HG) Using MR Spectroscopy
National Cancer Institute (NCI)
Phase II
Oncology
Glioma
HP 13C Pyruvate
SUSPENDED
OTHER/UNKNOWN
Study on hold pending possible updates with the team.
2026-07-02
Mesothelin-Specific T-Cells (FH-TCR-Tᴍsʟɴ) for the Treatment of Metastatic Pancreatic Ductal Adenocarcinoma
Fred Hutchinson Cancer Center
Phase I
Oncology
Metastatic Pancreatic Ductal Adenocarcinoma
Autologous Mesothelin-specific TCR-T Cells
TERMINATED
OPERATIONAL
Study terminated due to end of funding.
2026-07-02
CS1-CAR T Therapy Following Chemotherapy in Treating Patients With Relapsed or Refractory CS1 Positive Multiple Myeloma
City of Hope Medical Center
Phase I
Oncology
Recurrent Plasma Cell Myeloma
CS1-CAR T Therapy
SUSPENDED
OPERATIONAL
Slow/Low Accrual
2026-07-01
Total Marrow and Lymphoid Irradiation, Fludarabine, and Melphalan Before Donor Stem Cell Transplant in Treating Participants With High-Risk Acute Leukemia or Myelodysplastic Syndrome
City of Hope Medical Center
Phase I
Oncology
Acute Lymphoblastic Leukemia
Fludarabine
SUSPENDED
OPERATIONAL
Accrual goal
2026-07-01
Outpatient Treatment With Anti-Coronavirus Immunoglobulin
University of Minnesota
Phase III
Infectious Disease
COVID
Hyperimmune immunoglobulin to SARS-CoV-2 (hIVIG)
SUSPENDED
EFFICACY/FUTILITY
Stopped for futility - no safety issues.
2026-07-01
A Phase 1 Study of AOH1996 in Patients With Relapsed/Refractory Acute Myeloid Leukemia
City of Hope Medical Center
Phase I
Oncology
Recurrent Acute Myeloid Leukemia
Azacitidine
SUSPENDED
EFFICACY/FUTILITY
Pending Interim Analysis
2026-07-01
Study of TROP2 CAR Engineered IL15-transduced Cord Blood-derived NK Cells Delivered Intraperitoneally for the Management of Platinum Resistant Ovarian Cancer, Mesonephric-like Adenocarcinoma, and Pancreatic Cancer
M.D. Anderson Cancer Center
Phase I
Oncology
Pancreatic Cancer
TROP2-CAR-NK
SUSPENDED
OPERATIONAL
PI Request
2026-07-01
The Immune Effects of Fermented Wheat Germ Nutritional Supplementation in Patients With Advanced Solid Tumor Cancers Being Treated With Standard of Care Checkpoint Inhibitors
University of California, Davis
Phase I
Oncology
Advanced Colorectal Carcinoma
Fermented Wheat Germ Extract
SUSPENDED
EFFICACY/FUTILITY
For internal interim analysis
2026-07-01
Parenteral Ascorbic Acid Repletion in TransplantatIon
University of Wisconsin, Madison
Phase IV
Gastroenterology & Hepatology
Liver Transplant Failure and Rejection
Ascorbic acid
SUSPENDED
OTHER/UNKNOWN
Resources
2026-07-01
A Study Evaluating the Efficacy and Safety of Oral Etrasimod in the Treatment of Adult Participants With Moderately to Severely Active Crohn's Disease
Pfizer
Phase II
Gastroenterology & Hepatology
Crohn's Disease
Etrasimod
TERMINATED
EFFICACY/FUTILITY
The study was prematurely discontinued due to a lack of efficacy in sub-study 1
2026-07-01
Effect of Hyperglycaemia and Moxifloxacin on QTc Interval in T2DM
Richmond Pharmacology Limited
Unknown
Endocrine & Metabolic
Diabetes Type 2
glucose
TERMINATED
EFFICACY/FUTILITY
The study is being terminated early on the grounds of futility, as continuation of the study is no longer considered scientifically or operationally justified.
2026-07-01
A Study to Evaluate the Efficacy and Safety of MK-1167 in Participants With Alzheimer's Disease Dementia (MK-1167-008)
Merck Sharp & Dohme LLC
Phase II
Neurology
Alzheimer Disease
MK-1167
TERMINATED
OTHER/UNKNOWN
Termination Notes: Business reason
2026-07-01
A Study of PF-08046049/SGN-BB228 in Advanced Melanoma and Other Solid Tumors
Seagen, a wholly owned subsidiary of Pfizer
Phase I
Oncology
Cutaneous Melanoma
PF-08046049
TERMINATED
OPERATIONAL
The trial was terminated for strategic reasons. The decision was not based on any safety concerns.
2026-07-01
Bevacizumab, Fluorouracil, Leucovorin Calcium, and Oxaliplatin Before Surgery in Treating Patients With Stage II-III Rectal Cancer
University of Southern California
Phase II
Oncology
Mucinous Adenocarcinoma of the Rectum
bevacizumab
TERMINATED
OPERATIONAL
Insufficient Accrual
2026-07-01
Monitoring Early Response to Targeted Therapy in Stage IV HER2+ Breast Cancer Patients With Advanced PET/MR Imaging
University of Alabama at Birmingham
Phase I
Oncology
HER2-positive Breast Cancer
[18F]-FDG
WITHDRAWN
OPERATIONAL
Unable to recruit for this study.
2026-07-01
Neoadjuvant SGLT2 Inhibition in Localized Prostate Cancer
Washington University School of Medicine
Phase I
Oncology
Prostate Cancer
Dapagliflozin
TERMINATED
OPERATIONAL
Low accrual
2026-06-30
Ixazomib Citrate, Lenalidomide, Dexamethasone, and Zoledronic Acid or Zoledronic Acid Alone After Radiation Therapy in Treating Patients With Solitary Plasmacytoma of Bone
Alliance for Clinical Trials in Oncology
Phase III
Other
Solitary Osseous Plasmacytoma
ixazomib
TERMINATED
OPERATIONAL
DSMB recommendation due to slow accrual
2026-06-30
The Hunger Elimination or Reduction Objective (HERO ) Open -Label Extension (OLE) Trial
Aardvark Therapeutics, Inc.
Phase III
Other
Hyperphagia
ARD-101
TERMINATED
OTHER/UNKNOWN
Due to operational and regulatory considerations.
2026-06-30
Transition From Acute to Chronic Opioid Use and Chronic Pain
Jacques E. Chelly
Early Phase I
Other
Opioid Use Disorder
Opioid-free anesthesia
WITHDRAWN
OPERATIONAL
Study did not receive funding.
2026-06-30
Study of Magrolimab and Pembrolizumab in Relapsed or Refractory Classic Hodgkin Lymphoma
Ranjana Advani
Phase II
Oncology
Hodgkin Lymphoma
Magrolimab
TERMINATED
OTHER/UNKNOWN
Discontinuation of magrolimab development
2026-06-30
Does a Rescue Course of Betamethasone in Pregnant Women With PPROM Decrease Neonatal Morbidity?
The University of Texas Medical Branch, Galveston
Phase II
Respiratory
PPROM
Betamethasone
TERMINATED
OPERATIONAL
Low study recruitment
2026-06-30
Study of Obeldesivir to Treat Nonhospitalized Adults With Acute Respiratory Syncytial Virus (RSV) Infection
Gilead Sciences
Phase II
Infectious Disease
RSV Infection
Obeldesivir
TERMINATED
OPERATIONAL
Study was terminated by Sponsor; the decision was not due to any safety findings.
2026-06-30
A Study of Lebrikizumab in Adolescent Participants With Uncontrolled Asthma Who Are on Inhaled Corticosteroids and a Second Controller Medication
Hoffmann-La Roche
Phase III
Respiratory
Asthma
Lebrikizumab
TERMINATED
OPERATIONAL
Sponsor decision to discontinue lebrikizumab development for the treatment of asthma.
2026-06-30
Repeated Neural Stem Cell Based Virotherapy for Newly Diagnosed High Grade Glioma
Northwestern University
Phase I
Oncology
Glioma, Malignant
NSC-CRAd-S-pk7
SUSPENDED
SAFETY
Safety issues
2026-06-30
ARD-101 for Treatment of PWS: The Hunger Elimination or Reduction Objective Trial
Aardvark Therapeutics, Inc.
Phase III
Other
Hyperphagia
Placebo
TERMINATED
OTHER/UNKNOWN
Due to operational and regulatory considerations.
2026-06-30
Testing the Combination of Two Immunotherapy Drugs (Magrolimab and Dinutuximab) in Patients With Relapsed or Refractory Neuroblastoma or Relapsed Osteosarcoma
National Cancer Institute (NCI)
Phase I
Musculoskeletal
High Risk Neuroblastoma
Biospecimen Collection
TERMINATED
OPERATIONAL
Drug supply issues
2026-06-30
Study of Safety, Tolerability and Efficacy of PBKR03 in Pediatric Subjects With Early Infantile Krabbe Disease
Gemma Biotherapeutics
Phase I
Other
Leukodystrophy, Globoid Cell
PBKR03
SUSPENDED
OPERATIONAL
The study was stopped due to changes in the company strategy.
2026-06-30
Department of Defense PTSD Adaptive Platform Trial - Master Protocol
Global Coalition for Adaptive Research
Phase II
Other
Post Traumatic Stress Disorder
Intervention A Fluoxetine Hydrochloride (HCl)
SUSPENDED
OPERATIONAL
The trial has been temporarily suspended due to administrative issues
2026-06-30
Complex And Simple Appendicitis: REstrictive or Liberal Post-operative Antibiotic eXposure - UCSF
University of California, San Francisco
Phase IV
Other
Appendicitis
Multiple standard of care antibiotics for appendicitis, at physicians' discretion
TERMINATED
OPERATIONAL
Not feasible to complete trial due to low enrollment rate. Enrollment terminated and inadequately powered to achieve statistical significance on primary and secondary study outcomes.
2026-06-30
Department of Defense PTSD Adaptive Platform Trial - Intervention C - Daridorexant
Global Coalition for Adaptive Research
Phase II
Other
Post Traumatic Stress Disorder
Intervention C Daridorexant
SUSPENDED
OPERATIONAL
The trial has been temporarily suspended due to administrative issues
2026-06-30
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NCT02225600
The Effect of Oxytocin Administration on Interpersonal Cooperation in Borderline Personality Disorder Patients and Healthy Adults
Icahn School of Medicine at Mount Sinai
Last updated
2026-07-02
Why stopped
Study was halted during COVID pandemic. However, PI is currently reconnecting with a compounding pharmacy to re-establish supply of the oxytocin and updating cost estimates. We are hoping to resume the pilot work with oxytocin once it is clarified.
NCT05491317
A Safety and Antitumor Activity Trial of Immunoradiotherapy Combinations as a Treatment Option for Subjects With Metastatic Solid Tumors
Genmab
Last updated
2026-07-02
Why stopped
After reviewing all available data from Part 1 of the trial, the Sponsor has decided not to proceed to Part 2 (randomized Phase 2) of the trial due to lack of efficacy
NCT05652504
Safety Evaluation of PfSPZ Vaccine in Pregnant Women in Mali (MalVIP1)
National Institute of Allergy and Infectious Diseases (NIAID)
Last updated
2026-07-02
Why stopped
The study remains on hold due to a funding issue after it's been lifted by the FDA.
NCT07097311
Study to Evaluate the Use of Triheptanoin in Patients With Medium Chain Acyl-CoA Dehydrogenase Deficiency (MCADD)
Jerry Vockley, MD, PhD
Last updated
2026-07-02
Why stopped
funding was pulled
NCT01555554
Perioperative Propranolol in Patients With Post Traumatic Stress Disorder (PTSD)
University of California, San Francisco
Last updated
2026-07-02
Why stopped
Unable to meet enrollment goals
NCT05975905
A Study to Investigate the Safety and Efficacy of KER-012 in Combination With Background Therapy in Adult Participants With Pulmonary Arterial Hypertension (PAH) (TROPOS Study).
Keros Therapeutics, Inc.
Last updated
2026-07-02
Why stopped
The study was voluntarily terminated early, following a safety review and observation of pericardial effusions.
NCT02859896
Safety and Efficacy of Hectorol in Pediatric Patients With Chronic Kidney Disease Stage 3 and 4 With Secondary Hyperparathyroidism Not Yet on Dialysis
Sanofi
Last updated
2026-07-02
Why stopped
The study was conducted to fulfill a post-marketing commitment (PMC).FDA acknowledged the fulfillment of this PMC.
NCT05606315
RemImazolam Besylate for ICU-sedation in Patients With Mechanical Ventilation After Oral and Maxillofacial Surgery
Nanfang Hospital, Southern Medical University
Last updated
2026-07-02
Why stopped
The trial was terminated early because additional sites did not recruit as planned, making the multicenter sample size infeasible. Enrollment ended after 117 participants were randomized at Nanfang Hospital, unrelated to safety, efficacy, or outcomes
NCT06671912
Testing Low Dose Tamoxifen for Invasive Breast Cancer, LoTam Trial
Alliance for Clinical Trials in Oncology
Last updated
2026-07-02
Why stopped
Amending protocol to increase sample size
NCT03604991
Nivolumab and Ipilimumab in Treating Patients With Esophageal and Gastroesophageal Junction Adenocarcinoma Undergoing Surgery
National Cancer Institute (NCI)
Last updated
2026-07-02
Why stopped
End of Initial Phase of Multi-phase protocol
NCT04106856
Losartan and Hypofractionated Rx After Chemo for Tx of Borderline Resectable or Locally Advanced Pancreatic Cancer
University of Utah
Last updated
2026-07-02
Why stopped
Closed due to slow accrual
NCT04929041
Testing the Addition of Radiation Therapy to the Usual Treatment (Immunotherapy With or Without Chemotherapy) for Advanced Stage Non-small Cell Lung Cancer Patients Who Are PD-L1 Negative
National Cancer Institute (NCI)
Last updated
2026-07-02
Why stopped
End of Initial Phase of Multi-phase protocol
NCT07369791
Nivolumab Plus Relatlimab and Gemcitabine/Cisplatin as First-Line Treatment in Advanced Biliary Tract Cancer.
National Health Research Institutes, Taiwan
Last updated
2026-07-02
Why stopped
The study was terminated due to administrative reasons following the cancellation of collaboration between the involved parties.
NCT05642195
Evaluation of a Cancer Lysate Vaccine and Montanide (Registered Trademark) ISA-51 VG With or Without the IL-15 Super-Agonist N-803 as Adjuvant Therapy for PD-L1 Negative Non-Small Cell Lung Cancer
National Cancer Institute (NCI)
Last updated
2026-07-02
Why stopped
Revisions to eligibility/design being made prior to enrollment of first participants.
NCT05660967
Subcutaneous Epcoritamab With or Without Lenalidomide as First Line Therapy for Diffuse Large B-Cell Lymphoma
Genmab
Last updated
2026-07-02
Why stopped
The study was terminated because sufficient data had been collected to meet the objectives of the development program. No new or unexpected safety findings were identified, and the decision to terminate was not related to participant safety.
NCT06568172
Testing the Addition of an Immunotherapy Drug, Cemiplimab (REGN2810), Plus Surgery to the Usual Surgery Alone for Treating Advanced Skin Cancer
National Cancer Institute (NCI)
Last updated
2026-07-02
Why stopped
Other - Other
NCT04803201
Testing the Addition of Duvelisib or CC-486 to the Usual Treatment for Peripheral T-Cell Lymphoma
Alliance for Clinical Trials in Oncology
Last updated
2026-07-02
Why stopped
Interim Analysis
NCT05525247
A Phase 1/2, Open-label, Multicenter, Dose Escalation and Expansion Study of SLC-3010 Monotherapy and in Combination
Selecxine
Last updated
2026-07-02
Why stopped
Business decision
NCT06876142
Combination Therapy (Mirdametinib and Sirolimus) for RAS Mutated Relapsed Refractory Multiple Myeloma
National Cancer Institute (NCI)
Last updated
2026-07-02
Why stopped
Administrative hold pending non-safety related changes to the study design.
NCT06067802
Study of Triheptanoin for the Prevention of Hypoglycemia in Patients With Medium Chain Acyl-CoA Dehydrogenase Deficiency (MCADD)
Jerry Vockley, MD, PhD
Last updated
2026-07-02
Why stopped
Funding was pulled
NCT03952598
Studying the Biology of IDH-mutant Gliomas Via Longitudinal Observation of 2-hydroxyglutarate (2-HG) Using MR Spectroscopy
National Cancer Institute (NCI)
Last updated
2026-07-02
Why stopped
Study on hold pending possible updates with the team.
NCT04809766
Mesothelin-Specific T-Cells (FH-TCR-Tᴍsʟɴ) for the Treatment of Metastatic Pancreatic Ductal Adenocarcinoma
Fred Hutchinson Cancer Center
Last updated
2026-07-02
Why stopped
Study terminated due to end of funding.
NCT03710421
CS1-CAR T Therapy Following Chemotherapy in Treating Patients With Relapsed or Refractory CS1 Positive Multiple Myeloma
City of Hope Medical Center
Last updated
2026-07-01
Why stopped
Slow/Low Accrual
NCT03494569
Total Marrow and Lymphoid Irradiation, Fludarabine, and Melphalan Before Donor Stem Cell Transplant in Treating Participants With High-Risk Acute Leukemia or Myelodysplastic Syndrome
City of Hope Medical Center
Last updated
2026-07-01
Why stopped
Accrual goal
Last updated
2026-07-01
Why stopped
Stopped for futility - no safety issues.
NCT06763341
A Phase 1 Study of AOH1996 in Patients With Relapsed/Refractory Acute Myeloid Leukemia
City of Hope Medical Center
Last updated
2026-07-01
Why stopped
Pending Interim Analysis
NCT05922930
Study of TROP2 CAR Engineered IL15-transduced Cord Blood-derived NK Cells Delivered Intraperitoneally for the Management of Platinum Resistant Ovarian Cancer, Mesonephric-like Adenocarcinoma, and Pancreatic Cancer
M.D. Anderson Cancer Center
Last updated
2026-07-01
Why stopped
PI Request
NCT05967533
The Immune Effects of Fermented Wheat Germ Nutritional Supplementation in Patients With Advanced Solid Tumor Cancers Being Treated With Standard of Care Checkpoint Inhibitors
University of California, Davis
Last updated
2026-07-01
Why stopped
For internal interim analysis
Last updated
2026-07-01
Why stopped
Resources
NCT04173273
A Study Evaluating the Efficacy and Safety of Oral Etrasimod in the Treatment of Adult Participants With Moderately to Severely Active Crohn's Disease
Pfizer
Last updated
2026-07-01
Why stopped
The study was prematurely discontinued due to a lack of efficacy in sub-study 1
NCT07014735
Effect of Hyperglycaemia and Moxifloxacin on QTc Interval in T2DM
Richmond Pharmacology Limited
Last updated
2026-07-01
Why stopped
The study is being terminated early on the grounds of futility, as continuation of the study is no longer considered scientifically or operationally justified.
NCT06721156
A Study to Evaluate the Efficacy and Safety of MK-1167 in Participants With Alzheimer's Disease Dementia (MK-1167-008)
Merck Sharp & Dohme LLC
Last updated
2026-07-01
Why stopped
Termination Notes: Business reason
NCT05571839
A Study of PF-08046049/SGN-BB228 in Advanced Melanoma and Other Solid Tumors
Seagen, a wholly owned subsidiary of Pfizer
Last updated
2026-07-01
Why stopped
The trial was terminated for strategic reasons. The decision was not based on any safety concerns.
NCT01871571
Bevacizumab, Fluorouracil, Leucovorin Calcium, and Oxaliplatin Before Surgery in Treating Patients With Stage II-III Rectal Cancer
University of Southern California
Last updated
2026-07-01
Why stopped
Insufficient Accrual
NCT04273555
Monitoring Early Response to Targeted Therapy in Stage IV HER2+ Breast Cancer Patients With Advanced PET/MR Imaging
University of Alabama at Birmingham
Last updated
2026-07-01
Why stopped
Unable to recruit for this study.
NCT04887935
Neoadjuvant SGLT2 Inhibition in Localized Prostate Cancer
Washington University School of Medicine
Last updated
2026-06-30
Why stopped
Low accrual
NCT02516423
Ixazomib Citrate, Lenalidomide, Dexamethasone, and Zoledronic Acid or Zoledronic Acid Alone After Radiation Therapy in Treating Patients With Solitary Plasmacytoma of Bone
Alliance for Clinical Trials in Oncology
Last updated
2026-06-30
Why stopped
DSMB recommendation due to slow accrual
NCT07197034
The Hunger Elimination or Reduction Objective (HERO ) Open -Label Extension (OLE) Trial
Aardvark Therapeutics, Inc.
Last updated
2026-06-30
Why stopped
Due to operational and regulatory considerations.
Last updated
2026-06-30
Why stopped
Study did not receive funding.
NCT04788043
Study of Magrolimab and Pembrolizumab in Relapsed or Refractory Classic Hodgkin Lymphoma
Ranjana Advani
Last updated
2026-06-30
Why stopped
Discontinuation of magrolimab development
NCT02939742
Does a Rescue Course of Betamethasone in Pregnant Women With PPROM Decrease Neonatal Morbidity?
The University of Texas Medical Branch, Galveston
Last updated
2026-06-30
Why stopped
Low study recruitment
NCT06585150
Study of Obeldesivir to Treat Nonhospitalized Adults With Acute Respiratory Syncytial Virus (RSV) Infection
Gilead Sciences
Last updated
2026-06-30
Why stopped
Study was terminated by Sponsor; the decision was not due to any safety findings.
NCT01875003
A Study of Lebrikizumab in Adolescent Participants With Uncontrolled Asthma Who Are on Inhaled Corticosteroids and a Second Controller Medication
Hoffmann-La Roche
Last updated
2026-06-30
Why stopped
Sponsor decision to discontinue lebrikizumab development for the treatment of asthma.
NCT06169280
Repeated Neural Stem Cell Based Virotherapy for Newly Diagnosed High Grade Glioma
Northwestern University
Last updated
2026-06-30
Why stopped
Safety issues
NCT06828861
ARD-101 for Treatment of PWS: The Hunger Elimination or Reduction Objective Trial
Aardvark Therapeutics, Inc.
Last updated
2026-06-30
Why stopped
Due to operational and regulatory considerations.
NCT04751383
Testing the Combination of Two Immunotherapy Drugs (Magrolimab and Dinutuximab) in Patients With Relapsed or Refractory Neuroblastoma or Relapsed Osteosarcoma
National Cancer Institute (NCI)
Last updated
2026-06-30
Why stopped
Drug supply issues
NCT04771416
Study of Safety, Tolerability and Efficacy of PBKR03 in Pediatric Subjects With Early Infantile Krabbe Disease
Gemma Biotherapeutics
Last updated
2026-06-30
Why stopped
The study was stopped due to changes in the company strategy.
NCT05422612
Department of Defense PTSD Adaptive Platform Trial - Master Protocol
Global Coalition for Adaptive Research
Last updated
2026-06-30
Why stopped
The trial has been temporarily suspended due to administrative issues
NCT05966454
Complex And Simple Appendicitis: REstrictive or Liberal Post-operative Antibiotic eXposure - UCSF
University of California, San Francisco
Last updated
2026-06-30
Why stopped
Not feasible to complete trial due to low enrollment rate. Enrollment terminated and inadequately powered to achieve statistical significance on primary and secondary study outcomes.
NCT05948540
Department of Defense PTSD Adaptive Platform Trial - Intervention C - Daridorexant
Global Coalition for Adaptive Research
Last updated
2026-06-30
Why stopped
The trial has been temporarily suspended due to administrative issues
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